Protein Überblick

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Genbezeichner und Symbole assoziert mit F10

• coagulation factor X (F10) Antikörper
• coagulation factor X (f10) Antikörper
• coagulation factor X (CpipJ_CPIJ012712) Antikörper
• coagulation factor X (CpipJ_CPIJ014863) Antikörper
• coagulation factor X (CpipJ_CPIJ016937) Antikörper
• Alle Gen-Bezeichnungen
• coagulation factor X (CpipJ_CPIJ017791) Antikörper
• Coagulation factor X (fa10) Antikörper
• coagulation factor 10 L homeolog (f10.L) Antikörper

• Cf10 Antikörper
• f10 Antikörper
• fi12c10 Antikörper
• fX Antikörper
• FXA Antikörper
• Alle Synonyme
• wu:fi12c10 Antikörper

Bezeichner auf Proteinebene für F10

Stuart-Prower factor , factor Xa , prothrombinase , stuart factor , coagulation factor 10 , VAP , factor XA light chain , virus activating protease , virus-activating protease , coagulation factor X , vitamin K dependent serine protease , coagulation factor X preproprotein , blood coagulation factor X , Coagulation factor X , coagulation factor 10 L homeolog