Coagulation Factor X Antikörper

Produktnummer ABIN615558

Der Schaf Polyklonal anti-Coagulation Factor X Antikörper (ABIN615558) detektiert spezifisch Coagulation Factor X in IHC (p), IEP, EIA und ID. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Coagulation Factor X Antikörper (ABIN615558)

Target: Coagulation Factor X (F10)

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser Coagulation Factor X Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoelectrophoresis (IEP), Enzyme Immunoassay (EIA), Immunodiffusion (ID)

Produktdetails anti-Coagulation Factor X Antikörper

Spezifität: This antibody detects Coagulation factor X (F10). Only one arc was seen with normal plasma. No arc was seen with Factor X deficient plasma.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography

Immunogen: Human Factor X purified from plasma, activated and active site blocked

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: 10 mM HEPES, pH 7.4, 0.15 M Sodium Chloride, 50 % Glycerol

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Coagulation Factor X

Target: Coagulation Factor X (F10)

Hintergrund: F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.Synonyms: Stuart factor, Stuart-Prower factor

Gen-ID: 2159

NCBI Accession: NP_000495

UniProt: P00742