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CHD3 encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains.
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Human Monoclonal CHD3 Primary Antibody für FACS, IF - ABIN965879
Lepesheva, Virus, Waterman: Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function. in Biochemistry 2003
Show all 3 Pubmed References
Human Monoclonal CHD3 Primary Antibody für ICC, FACS - ABIN969052
Burd, Kinyamu, Miller, Archer: UV radiation regulates Mi-2 through protein translation and stability. in The Journal of biological chemistry 2008
Human Polyclonal CHD3 Primary Antibody für ICC, IF - ABIN253030
Alfonso, Lutz, Rodriguez, Chavez, Rodriguez, Gutierrez, Nieto: CHD6 chromatin remodeler is a negative modulator of influenza virus replication that relocates to inactive chromatin upon infection. in Cellular microbiology 2011
Human Monoclonal CHD3 Primary Antibody für ELISA, FACS - ABIN4297875
Wille, Maurer, Piatti, Whittle, Rieder, Singewald, Lusser: Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors. in Frontiers in behavioral neuroscience 2015
Fruit Fly (Drosophila melanogaster) Monoclonal CHD3 Primary Antibody für ICC, IF - ABIN2668246
Murawska, Kunert, van Vugt, Längst, Kremmer, Logie, Brehm: dCHD3, a novel ATP-dependent chromatin remodeler associated with sites of active transcription. in Molecular and cellular biology 2008
dCHD3 exists as a monomer
The tandem PHD (zeige PDC Antikörper) fingers of CHD3 bind histone H3 (zeige HIST3H3 Antikörper) tails.
CHD3 and CHD4 (zeige CHD4 Antikörper) exhibit distinct nuclear localization patterns in unperturbed cells, revealing a subset of specific target genes.
Mutations in CHD3 gene is associated with cutaneous T cell lymphoma and Sezary syndrome.
CHD3 was confirmed to interact with NES1 (zeige KLK10 Antikörper) in NS2, and a disruption to this interaction by mutation in NES1 (zeige KLK10 Antikörper) significantly delayed viral vRNPs export and viral propagation.
CHD3.1 and ACF1 (zeige BAZ1A Antikörper)-SNF2H (zeige SMARCA5 Antikörper) display counteractive activities but similar histone affinities.
In this study, the chromatin remodeler chromodomain helicase DNA binding (CHD3) protein is identified as an important component of the initial repression of the herpesvirus genome.
effect of progressive C-terminal deletions of CHD3, which indicated that sequences required for repression of PS1 (zeige PSEN1 Antikörper) lie between amino acids 1955 and 1877
Pericentrin (zeige PCNT Antikörper) forms complexes with CHD3 and CHD4 (zeige CHD4 Antikörper), but a distinct CHD3-pericentrin (zeige PCNT Antikörper) complex is required for centrosomal anchoring of pericentrin (zeige PCNT Antikörper)/gamma-tubulin (zeige TUBG1 Antikörper) and for centrosome integrity.
UV radiation regulates Mi-2 (zeige CHD4 Antikörper) through protein translation and stability
results suggest that ZFH/Chd3 might play an important role in tooth root development and subsequent cementogenesis.
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
, chromodomain helicase DNA binding protein 3
, similar to CHD3
, chromodomain-helicase-DNA-binding protein 3-like
, ATP-dependent helicase CHD3
, chromodomain-helicase-DNA-binding protein 3
, mi-2 autoantigen 240 kDa protein
, zinc finger helicase
, zinc-finger helicase (Snf2-like)
, Mi-2 alpha
, CHD3-like protein