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Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. Zusätzlich bieten wir Ihnen Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Kits (72) und Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Proteine (24) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal CHI3L1 Primary Antibody für ELISA - ABIN2472953
Iwarson: [The pattern of non-A, non-B hepatitis is more and more evident. A new test for diagnosis of hepatitis C makes it possible to mass screen blood donors]. in Läkartidningen 1990
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Cow (Bovine) Polyclonal CHI3L1 Primary Antibody für IF, WB - ABIN2784693
Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008
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miR (zeige MLXIP Antikörper)-24 serves as a molecular regulator in S. aureus-induced macrophage polarization through targeting of CHI3L1 and regulation of the MAPK (zeige MAPK1 Antikörper) pathway
The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo
CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (zeige S100A9 Antikörper) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (zeige S100A9 Antikörper) receptor, RAGE (zeige AGER Antikörper) (Receptor for Advanced Glycation End products).
IL-18 (zeige IL18 Antikörper) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (zeige IL18 Antikörper)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.
CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.
Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.
Results do not support a role of BRP (zeige GDF5 Antikörper)-39 in the pathogenesis of experimental autoimmune encephalitis.
CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.
mechanism of BRP (zeige GDF5 Antikörper)-39 in bleomycin-induced pulmonary fibrosis
Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis
YKL-40 was expressed by macrophages in liver tissue of NAFLD (zeige TSC2 Antikörper) patients.
The results of this study indicate that YKL-40 may contribute to decreased stability and increased permeability of BBB (zeige ALMS1 Antikörper) in AD patients
YKL-40 is expressed by a subset of astrocytes in Alzheimer's disease and other tauopathies.
This study has shown that YKL-40 serum level is increased in patients with atopic dermatitis and reflects the severity of symptoms.
YKL-40 levels were found to be significantly higher in post-infectious bronchiolitis obliterans (PIBO) patients with exacerbation compared with that in bronchiolitis patients and showed a positive correlation with the severity of disease before diagnosis of PIBO.
High YKL-40 expression is independently and markedly associated with worse overall survival in glioblastoma patients.
Datashow that patients with YKL-40 overexpression had significantly shorter survival time than those with low YKL-40 expression.
The level of serum YKL-40 is a significant and independent biomarker to predict the clinical outcome in large-artery atherosclerotic stroke.
TrkB (zeige NTRK2 Antikörper)-containing exosomes play a key role in the control of glioblastoma progression and aggressiveness, as seen in a model of YKL-40-inactivated glioblastoma cells
chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation
Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.
, cartilage glycoprotein 39
, chitinase-3-like protein 1
, 39 kDa synovial protein
, 38 kDa heparin-binding glycoprotein
, signal-processing protein
, 39 kDa whey protein
, 40 kDa secretory signalling glycoprotein
, cartilage glycoprotein-39
, chitinase-like protein 1
, signal processing protein
, chitinase 3-like 1 protein
, mammary gland protein 40