anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antikörper

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus CHI3L1 CHI3L1 12654 Q61362
Anti-Human CHI3L1 CHI3L1 1116 P36222
Anti-Ratte CHI3L1 CHI3L1 89824 Q9WTV1
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Top anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antikörper auf antikoerper-online.de

Showing 10 out of 116 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IF, WB <b>WB Suggested Anti-CHI3L1 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert EIA, IHC (p), WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of YKL-40 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Human Serum. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$332.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Maus Unkonjugiert ELISA, WB Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - SW480 cell lysate (40ug) was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CHI3L1 (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Western Blot: Chitinase 3-like 1 Antibody (2C10) [NBP1-28610] - Cell lysates of HepG2 (35ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human CHI3L1 (1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Anmelden zum Anzeigen 12 bis 15 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extract of various cells, using CHI3L1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Maus Kaninchen Unkonjugiert ELISA, WB Western blot analysis of CHI3L1 using anti-CHI3L1 antibody . Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.  Lane 1: mouse RAW264.7 whole cell lysates, Lane 2: mouse HEPA1-6 whole cell lysates. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-CHI3L1 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 ug/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for CHI3L1 at approximately 43KD. The expected band size for CHI3L1 is at 43KD. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert FACS, IF (p), IHC (p) HepG2 cells probed with Rabbit Anti-CHI3L1 Polyclonal Antibody  Alexa Fluor 488 Secondary 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$306.90
Details
Human Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$163.90
Details

Am meisten referenzierte anti-Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Antikörper

  1. Human Monoclonal CHI3L1 Primary Antibody für ELISA - ABIN2472953 : Iwarson: [The pattern of non-A, non-B hepatitis is more and more evident. A new test for diagnosis of hepatitis C makes it possible to mass screen blood donors]. in Läkartidningen 1990 (PubMed)
    Show all 4 Pubmed References

  2. Cow (Bovine) Polyclonal CHI3L1 Primary Antibody für IF, WB - ABIN2784693 : Ober, Tan, Sun, Possick, Pan, Nicolae, Radford, Parry, Heinzmann, Deichmann, Lester, Gern, Lemanske, Nicolae, Elias, Chupp: Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function. in The New England journal of medicine 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Chitinase 3-Like 1 (Cartilage Glycoprotein-39) Interaktionspartner

Mouse (Murine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Interaktionspartner

  1. miR (zeige MLXIP Antikörper)-24 serves as a molecular regulator in S. aureus-induced macrophage polarization through targeting of CHI3L1 and regulation of the MAPK (zeige MAPK1 Antikörper) pathway

  2. The mouse model was used to validate the function of CHI3L1 in cancer metastasis in vivo

  3. CHI3L1-mediated cell proliferation/survival involves partial downregulation of the pro-apoptotic S100A9 (zeige S100A9 Antikörper) protein that is highly expressed during the acute phase of colitis, by binding to the S100A9 (zeige S100A9 Antikörper) receptor, RAGE (zeige AGER Antikörper) (Receptor for Advanced Glycation End products).

  4. IL-18 (zeige IL18 Antikörper) is a potent stimulator of Chi3l1 and that Chi3l1 is an important mediator of IL-18 (zeige IL18 Antikörper)-induced inflammatory, fibrotic, alveolar remodeling, and cytotoxic responses.

  5. CHI3L1 is induced during fungal infection, and it regulated antifungal innate immune responses in the cornea.

  6. Astrocytic expression of chitinase 3-like protein 1 limits the extent of both astrocytic and microglial/macrophage facets of neuroinflammation.

  7. Results do not support a role of BRP (zeige GDF5 Antikörper)-39 in the pathogenesis of experimental autoimmune encephalitis.

  8. CHI3L1 was increased in plasma and brain tissue in experimental cerebral malaria, but targeted Chi3l1 deletion did not alter cytokine production or survival in this model.

  9. mechanism of BRP (zeige GDF5 Antikörper)-39 in bleomycin-induced pulmonary fibrosis

  10. Sem7a and its receptors regulate Chi3l1 in pulmonary melanoma metastasis

Human Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Interaktionspartner

  1. YKL-40 could be considered as a useful biomarker of inflammation in psoriasis and is more sensitive than CRP (zeige CRP Antikörper) or WBC. Increased YKL-40 may indicate psoriatic patients with a higher level of systemic inflammation, which may determine disease management.

  2. YKL-40 protein expression associated with severe lung function impairment and severe exacerbations in Asthma patients.

  3. Results suggest a potential role of chitinase 3 like 1 protein (CHI3L1) in angiogenesis in invasive ductal breast carcinoma (IDC (zeige LMNA Antikörper)) and may suggest its involvement in cancer progression.

  4. YKL-40 is a promising biomarker for evaluating polymyositis/dermatomyositis-associated interstitial lung disease activity/severity and predicting disease prognosis.

  5. Early-onset atopic dermatitis was associated with rs2303067 in SPINK5 (zeige SPINK5 Antikörper), which is involved in skin barrier functioning, and late-onset was associated with rs4950928 in CHI3L1, which is involved in the immune response. Future studies should examine the early- versus late-onset subgrouping more closely.

  6. YKL-40 may represent a novel biomarker for predicting hypertension risk in prehypertension population

  7. A high diagnostic sensitivity of YKL-40 in the early stages of the disease suggests the possibility of using this biomarker at an early diagnostic phase of patients with endometrial cancer. The patients with increased levels of YKL-40 before treatment are also at the higher risk of relapse.

  8. Serum YKL-40 was elevated only in atrial fibrllation and not in other supraventricular arrhythmias.

  9. YKL-40 is elevated in serum and bronchoalveolar lavage fluid of pulmonary alveolar proteinosis (PAP (zeige REG3A Antikörper)) patients, and may be of clinical utility to predict outcome in PAP (zeige REG3A Antikörper)

  10. YKL-40 was expressed by macrophages in liver tissue of NAFLD (zeige TSC2 Antikörper) patients.

Cow (Bovine) Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Interaktionspartner

  1. chitinase-like lectin, YKL-40, binds specifically to type I collagen and modulates the rate of type I collagen fibril formation

Chitinase 3-Like 1 (Cartilage Glycoprotein-39) (CHI3L1) Antigen-Profil

Protein Überblick

Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling.

Genbezeichner und Symbole assoziert mit CHI3L1

  • chitinase-like 1 (Chil1) Antikörper
  • chitinase 3 like 1 (CHI3L1) Antikörper
  • chitinase 3-like 1 (cartilage glycoprotein-39) (CHI3L1) Antikörper
  • chitinase 3 like 1 (Chi3l1) Antikörper
  • ASRT7 Antikörper
  • AW208766 Antikörper
  • BP40 Antikörper
  • Brp39 Antikörper
  • CGP-39 Antikörper
  • Chil1 Antikörper
  • CLP-1 Antikörper
  • GP-39 Antikörper
  • GP38K Antikörper
  • GP39 Antikörper
  • HC-gp39 Antikörper
  • HCGP-3P Antikörper
  • hCGP-39 Antikörper
  • MGP-40 Antikörper
  • SPC-40 Antikörper
  • SPS-40 Antikörper
  • YKL-40 Antikörper
  • YKL40 Antikörper
  • YYL-40 Antikörper

Bezeichner auf Proteinebene für CHI3L1

CGP-39 , GP-39 , cartilage glycoprotein 39 , chitinase-3-like protein 1 , 39 kDa synovial protein , 38 kDa heparin-binding glycoprotein , signal-processing protein , 39 kDa whey protein , 40 kDa secretory signalling glycoprotein , cartilage glycoprotein-39 , chitinase-like protein 1 , signal processing protein , chitinase 3-like 1 protein , mammary gland protein 40

GENE ID SPEZIES
12654 Mus musculus
1116 Homo sapiens
396865 Sus scrofa
286869 Bos taurus
89824 Rattus norvegicus
100860825 Capra hircus
443279 Ovis aries
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