anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Antikörper

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 (zeige CCL2 Antikörper) mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR (zeige MYLIP Antikörper)-21.

4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. Age-related epigenetic and genetic factors which contribute to the dysregulation of CXCL10.

2. COMMD7 (zeige COMMD7 Antikörper) activates CXCL10 production by regulating NFkappaB (zeige NFKB1 Antikörper) and the production of ROS (zeige ROS1 Antikörper). The present study highlighted the role of COMMD7 (zeige COMMD7 Antikörper) in the development of HCC (zeige FAM126A Antikörper), and provides novel options for anticancer drug design.

3. Nab-PTX treatment could increase CXCL10 expression.

4. The frequency of non-classical monocytes spontaneously producing CXCL10 was increased in both limited and diffuse systemic sclerosis

5. serum levels in active vitiligo (zeige MITF Antikörper) significantly elevated compared to those in stable vitiligo (zeige MITF Antikörper) patients

6. Plasma CXCL10 levels are significantly higher in SPs (zeige SMS Antikörper) pre-HAART and RPs (zeige RPS3 Antikörper) pre-HAART when compared with HIV-negative controls.

7. Hepatitis b vaccine was efficient in enhancing IP-10 level with HBsAg clearance, or reduction to a favorable level.

8. Results show that the expression of IP-10 in peripheral blood of patients with HBV-associated acute-on-chronic liver failure (HBV-ACLF) was significantly high and correlated with the severity of liver failure. IP-10 played an important role in the pathogenesis and progression of HBV-ACLF.

9. Differential regulation of cytokine release at both transcriptional and post-transcriptional levels, suppresses type-I-IFN induction yet allows for CXCL10 secretion during imDNA-induced cellular stress.

10. the elevated concentrations of CXCL13 (zeige CXCL13 Antikörper), CXCL8 (zeige IL8 Antikörper), and CXCL10 or their increasing CSF (zeige CSF2 Antikörper)/serum ratios may be potential biomarkers of neurosyphilis

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. Study shows that circulating interferon (zeige IFNA Antikörper)- that binds to receptors on brain endothelial cells and induces Cxcl10, is a central link in the signaling chain eliciting inflammation-induced aversion.

2. The knockout of either CXCL10 or TNF-alpha (zeige TNF Antikörper) reduced germ cell apoptosis in the co-cultures of germ cells and Sertoli cells in response to MuV infection. Local injection of MuV into the testes of mice confirmed the involvement of CXCL10 in germ cell apoptosis in vivo.

3. CXCL10 has strong inhibitory effects on neovascularization, whereas MMP13 (zeige MMP13 Antikörper) is required for neovascularization in C. albicans-infected corneas.

4. Study provided the evidence that CXCL10/CXCR3 (zeige CXCR3 Antikörper) signaling in periaqueductal gray is involved in the development of morphine analgesic tolerance via neuron-microglia interaction.

5. Results suggest that CXCL10(-/-) mice are protected against diet-induced nonalcoholic steatohepatitis (NASH (zeige SAMSN1 Antikörper)), in an obesity-independent manner.

6. In conclusion, upregulated CXCL10 in steatohepatitis impairs autophagic flux by reducing autolysosome formation, thereby inhibiting autophagic protein degradation and the accumulation of ubiquitinated proteins, leading to the development of steatohepatitis.

7. These findings highlight the importance of CXCL10 signaling in the pathogenesis of rheumatoid arthritis and provide previously unidentified details of the mechanisms by which CXCL10 promotes the development of arthritis.

8. Study revealed that CXCL10 evoked an ionic current mainly carried by Cl(-) channels, suggests that Cl(-) channels are likely key molecular candidates responsible for the CXCL10-evoked neuronal activation and itch-like behaviors in a murine model of allergic contact dermatitis induced by the antigen squaric acid dibutylester. Cl(-) channels may emerge as a promising drug target for the treatment of allergic itch.

9. Collectively, these results suggest that the CXCL10/CXCR3 (zeige CXCR3 Antikörper)-mediated NF-kappaB (zeige NFKB1 Antikörper) signaling pathway plays a role in the control of autonomous regulation of CXCL10 and malignant tumor properties in breast cancer 4T1 cells.

10. results show an important role for CXCR3 (zeige CXCR3 Antikörper) and CXCL10 in the tissue distribution of preimmune memory phenotype CD8 (zeige CD8A Antikörper) T- cells

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF (zeige CSF2 Antikörper) gene transcription.

2. IL-17A (zeige IL17A Antikörper) was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.