anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Antikörper

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. a SNP in CXCL10 was significantly associated with percentage of lymphocyte in blood of 20-day-old pigs and with hematocrit and mean red cell volume in blood of 80-day-old pigs

2. CXCL10 protein was detected in serum from pigs infected with a high virulence African swine fever virus isolate. Levels of CCL2 (zeige CCL2 Antikörper) mRNA were increased in pigs infected with the high virulence isolate compared to a low virulence isolate.

3. Authors identified chemokine (C-X-C motif) ligand 10 (CXCL10), also named interferon-gamma inducible protein-10 (IP-10), as a novel target gene of miR (zeige MYLIP Antikörper)-21.

4. These in vitro and in vivo observations suggest that interferon-gamma inducible protein 10 (IP-10) may be a reliable biomarker for immune activity induced by CpG oligodeoxynucleotides in pigs.

5. The swine CXCL10 gene contains four exons and three introns.

Human Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. Interferon-gamma-inducible protein 10 (IP-10) directly promoted hepatocyte apoptosis, and baseline IP-10 levels may predict the decrease in the hepatitis B surface antigen levels after entecavir therapy in patients with chronic hepatitis B.

2. data indicate that IP-10 is associated with disease activity and perseverance of rheumatoid arthritis.

3. CXCL10 in addition to IFN-gamma (zeige IFNG Antikörper) can be used to differentiate among Mycobacterium tuberculosis infection possibilities.

4. Increased amniotic fluid CXCL10 concentration is associated with chronic chorioamnionitis or maternal anti-fetal rejection, whereas increased amniotic fluid IL-6 (zeige IL6 Antikörper) concentration is associated with acute histologic chorioamnionitis.

5. Cord blood CXCL10 levels were negatively associated with mite sensitization at age 3. A high cord blood CCL22 (zeige CCL22 Antikörper)/CXCL10 chemokine (zeige CCL1 Antikörper) ratio was significantly associated with a higher risk of allergic sensitization at age 3.

6. CXCL10/IP-10 transcript showed up to 20 fold-increase, with similar changes detectable at the protein level in melanoma cells overexpressing PDFGRA.

7. this study suggests that GG genotype of CXCL10 -135G/A (rs56061981) polymorphism decreased CXCL10 expression in T cells which may have defective recruitment of mononuclear cells at the site of infection as well granuloma formation and in turn contribute to progression of tuberculosis

8. The regular early post-transplantation monitoring of urinary miR (zeige MLXIP Antikörper)-155-5p and CXCL10 can help in the prognosis of acute rejection and graft dysfunction after kidney transplantation.

9. gene polymorphisms of IL-8 (zeige IL8 Antikörper)(-251T/A) and IP-10(-1596C/T) are associated with susceptibility and progression of type 2 diabetic retinopathy in a northern Chinese population

10. Higher serum levels of CXCL10 are found in patients with non-segmental vitiligo (zeige MITF Antikörper) (NSV) and NSV + autoimmune thyroiditis than in controls.

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. Study revealed that CXCL10 evoked an ionic current mainly carried by Cl(-) channels, suggests that Cl(-) channels are likely key molecular candidates responsible for the CXCL10-evoked neuronal activation and itch-like behaviors in a murine model of allergic contact dermatitis induced by the antigen squaric acid dibutylester. Cl(-) channels may emerge as a promising drug target for the treatment of allergic itch.

2. Collectively, these results suggest that the CXCL10/CXCR3 (zeige CXCR3 Antikörper)-mediated NF-kappaB (zeige NFKB1 Antikörper) signaling pathway plays a role in the control of autonomous regulation of CXCL10 and malignant tumor properties in breast cancer 4T1 cells.

3. results show an important role for CXCR3 (zeige CXCR3 Antikörper) and CXCL10 in the tissue distribution of preimmune memory phenotype CD8 (zeige CD8A Antikörper) T- cells

4. In lipotoxic hepatocytes, MLK3 (zeige KCNK7 Antikörper) activates a MAPK (zeige MAPK1 Antikörper) signaling cascade, resulting in the activating phosphorylation of STAT1 (zeige STAT1 Antikörper), and CXCL10 transcriptional upregulation.

5. These findings elucidate an NFAT (zeige NFATC1 Antikörper)-MAPK (zeige MAPK1 Antikörper) signaling paradigm for induction of isletokine expression in beta-cells and reveal IP-10 as a primary therapeutic target to prevent beta-cell-induced inflammatory loss of graft function after islet cell transplantation.

6. A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines in inflammatory bowel diseases has been described.

7. this study shows that poly I:C treated PAR-1 (zeige MARK2 Antikörper)-/- mice given the thrombin (zeige F2 Antikörper) inhibitor dabigatran etexilate exhibited less IFNbeta and CXCL10 expression in the spleen and plasma

8. ATF3 (zeige ATF3 Antikörper)-KO mice escape from PE-dependent maladaptive cardiac remodeling by suppressing the IFNgamma-CXCL10-CXCR3 (zeige CXCR3 Antikörper) axis at multiple levels.

9. this study shows that neutrophils and NK cells act as important disease-promoting immune cells in experimental osteoarthritis and their functional interaction is promoted by the CXCL10/CXCR3 (zeige CXCR3 Antikörper) axis

10. CXCL10 chemokine (zeige CCL1 Antikörper) levels correlate negatively with gremlin-1 (zeige GREM1 Antikörper) levels in mouse and human lung.

Cow (Bovine) Chemokine (C-X-C Motif) Ligand 10 (CXCL10) Interaktionspartner

1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 and GM-CSF (zeige CSF2 Antikörper) gene transcription.

2. IL-17A (zeige IL17A Antikörper) was shown to be upregulated, supporting its investigation as a potential biomarker of bTB.