anti-Chemokine (C-C Motif) Ligand 8 (CCL8) Antikörper

Human Chemokine (C-C Motif) Ligand 8 (CCL8) Interaktionspartner

1. Transcriptome analysis identified several novel IPF-related genes. Among them, CCL8 is a candidate molecule for the differential diagnosis and prediction of survival.

2. Findings exemplify how gradients of chemoattractive factors such as CCL8, drive metastasis and suggest that interference with their operation may provide means for breast cancer management.

3. Detecting expression changes in TLR4 (zeige TLR4 Antikörper) and MCP2 in the peripheral blood is a feasible method for predicting the occurrence of abortion in women of child-bearing age

4. Dermal fibroblast CCL8 promotes melanoma metastasis.

5. Authors show that the previously observed downregulation of hsa (zeige CD24 Antikörper)-miR (zeige MLXIP Antikörper)-92a and upregulation of CCL8 during human cytomegalovirus latent infection of myeloid cells are intimately linked via the latency-associated expression of cytomegalovirus UL111A.

6. CCL8 is an antimicrobial protein with bacteriocidal activity against E. coli.

7. JAK2 (zeige JAK2 Antikörper) and STAT3 (zeige STAT3 Antikörper) activation is not essential for CCL3 (zeige CCL3 Antikörper), CCL5 (zeige CCL5 Antikörper) or CCL8 induced chemotaxis.

8. Results indicate that the induction of MCP-2/CCL8 by mycobacteria is dependent on the activation of TLR2/PI3K (zeige PIK3CA Antikörper)/Akt (zeige AKT1 Antikörper) signaling pathway.

9. Macrophage Colony Stimulating Factor (zeige CSF2 Antikörper) and Monocyte Chemoattractant Protein are elevated in sera of intrinsic asthmatics compared to normal controls.

10. Cytokine treatment increases mRNA stability only for chemokines CCL2 (zeige CCL2 Antikörper) and CCL8 in airway epithelium, and transient silencing and overexpression of human antigen R affects only chemokine (zeige CCL1 Antikörper) CCL2 (zeige CCL2 Antikörper) and CCL8 expression in primary and transformed epithelial cells.

Mouse (Murine) Chemokine (C-C Motif) Ligand 8 (CCL8) Interaktionspartner

1. Findings exemplify how gradients of chemoattractive factors such as CCL8, drive metastasis and suggest that interference with their operation may provide means for breast cancer management.

2. tumours are characterized by expression of inflammatory chemokines (CCL2 (zeige CCL2 Antikörper), CCL5 (zeige CCL5 Antikörper), CCL7 (zeige CCL7 Antikörper), CCL8, CCL12 (zeige Ccl12 Antikörper), CXCL9 (zeige CXCL9 Antikörper), CXCL10 (zeige CXCL10 Antikörper) and CX3CL1 (zeige CX3CL1 Antikörper)), reflected by an enrichment of activated Foxp3 (zeige FOXP3 Antikörper)(-) and Foxp3 (zeige FOXP3 Antikörper)(+) T cells

3. these data reveal an important role for BLIMP1 (zeige PRDM1 Antikörper) in modulating host defenses by suppressing expression of the chemokine (zeige CCL1 Antikörper) CCL8.

4. Results indicate that the induction of MCP-2/CCL8 by mycobacteria is dependent on the activation of TLR2/PI3K/Akt (zeige AKT1 Antikörper) signaling pathway.

5. Data indicate mRNA upregulation of CCR2 (zeige CCR2 Antikörper) and CCR2 (zeige CCR2 Antikörper) ligands CCL2 (zeige CCL2 Antikörper), CCL7 (zeige CCL7 Antikörper), CCL8, and CCL12 (zeige Ccl12 Antikörper) in aortas from DOCA/salt-treated hypertension.

6. Vitamin B6 supplementation downregulates Cd8a (zeige CD8A Antikörper) and Ccl8 mRNA expression, so these candidate genes may play a protective role against colonic aberrant crypt foci development.

7. early and preclinical expression of CCL8 in plasma predicts overall survival of graft-vs.-host disease (GVHD) mice. Together with an involvement of allo-recognition in CCL8 expression, it suggests that CCL8 plays an important role in GVHD pathology.

8. MCP (zeige CR1L Antikörper)/CCL8 was induced via STAT3 (zeige STAT3 Antikörper) and exhibited anti-tumor metastatic effect

9. promotes atopic dermatitis by recruiting IL-5 (zeige IL5 Antikörper)+ Th2 cells

10. CCL8 proteins were present in the vast majority of tissues investigated. mRNA for these proteins was also expressed in most of these tissues suggesting local production and the ability to respond in situ to inflammatory stimuli.