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CRABP2 encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. Zusätzlich bieten wir Ihnen CRABP2 Antikörper (161) und CRABP2 Kits (18) und viele weitere Produktgruppen zu diesem Protein an.
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These data suggest a retinoic acid-independent, non-tumor suppressor role of CRABP2 for the survival of Malignant peripheral nerve sheath tumor (MPNST) cells in vitro. Targeting CRABP2 overexpression may represent a unique approach for the treatment of human MPNST.
A high expression ratio between FABP5 (zeige FABP5 Proteine) and CRABPII may be related to CP tumor recurrence and ATRA could be a potential therapeutic agent for CP chemotherapy.
Holo-CRABPs had higher affinity for CYP26B1 (zeige CYP26B1 Proteine) than free atRA, but both apo (zeige C9orf3 Proteine)-CRABPs(CRABP-I (zeige CRABP1 Proteine) and CRABP-II ) inhibited the formation of 4-OH-RA by CYP26B1 (zeige CYP26B1 Proteine).
reducing CRABP2 levels may enhance the therapeutic index of Retinoic acid in glioblastoma multiforme patients
The anticarcinogenic activities of CRABP2 are mediated by both HuR (zeige ELAVL1 Proteine) and RAR (zeige RARA Proteine).
CBX3 (zeige CBX3 Proteine) and CRABP2 expression was markedly increased in lung cancer tissues
we demonstrated significant changes in CRABP1 (zeige CRABP1 Proteine) and CRABP2 expression in non-small cell lung cancer samples
Reengineering of cellular retinoic acid binding protein II (CRABPII) to be capable of binding retinal as a protonated Schiff base is described
CRABP2 controls mRNA stabilization by HuR (zeige ELAVL1 Proteine).
Factors involved in the retinoid pathway, in particular upregulation of CRBP (zeige RBP1 Proteine), CRABP1 (zeige CRABP1 Proteine) and CRABP2, also showed differential expression in tumors with different histological subtypes
Chromosome mapping of CRABP1 (zeige RBP1 Proteine) AND CRABP2 in swine.
Zebrafish Crabp2a and Crabp2b are essential for expression of hoxb4 (zeige HOXB4 Proteine) and hoxb5 (zeige HOXB5 Proteine) in the hindbrain.
Results show that acetylation status of CRABPII directly influences embryonic stem cell differentiation in response to retinoic acid.
all three proteins (RDH10 (zeige RDH10 Proteine), RALDH2 (zeige ALDH1A2 Proteine), and CRABP2) appeared to be required for ATRA production induced by activation of PPARgamma (zeige PPARG Proteine)
CRABP2 promotes myoblast differentiation and is modulated by the transcription factors MyoD (zeige MYOD1 Proteine) and Sp1 (zeige SP1 Proteine) in C2C12 cells.
observations emphasize the important role of CRABP-II in regulating the transcriptional activity of RA through RAR (zeige RARA Proteine), and they demonstrate that repression of this gene is critical for allowing adipogenesis to proceed
Localization revealed epithelial-mesenchymal interactions, differentiation differences within the retinoic acid biosynthesis and signaling pathway, and observations on nuclear versus cytoplasmic locations of Crabp2 and RA receptors (alpha, beta, gamma).
Increases in CRABPI (zeige CRABP1 Proteine) and II transcripts in the absence of leukemia inhibitory factor (zeige LIF Proteine) may regulate aspects of embryonic stem cell differentiation in response to retinol.
TIS7 (zeige IFRD1 Proteine) inhibits CRABP II expression during axonal regeneration, thereby modulating retinoic acid signalling. Hence, neurite initiation and branching are regulated by a negative feedback mechanism involving TIS7 (zeige IFRD1 Proteine) and CRABP II.
This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
cellular retinoic acid binding protein 2
, cellular retinoic acid-binding protein 2
, cellular retinoic acid-binding protein II
, cellular lipid-binding protein
, cellular retinoic acid binding protein II