anti-Cathepsin C (CTSC) Antikörper

The protein encoded by CTSC, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. Zusätzlich bieten wir Ihnen Cathepsin C Kits (38) und Cathepsin C Proteine (19) und viele weitere Produktgruppen zu diesem Protein an.

Gen	GeneID	UniProt
CTSC	1075	P53634
CTSC	13032	P97821
CTSC	25423	P80067

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Top anti-Cathepsin C Antikörper auf antikoerper-online.de

Showing 10 out of 97 products:

Katalog Nr.	Reaktivität	Wirt	Konjugat	Applikation	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN2788336	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	100 μL	Anmelden zum Anzeigen	2 bis 3 Tage	$289.00	Details
ABIN2788337	Human	Kaninchen	Unkonjugiert	IHC, WB	100 μL	Anmelden zum Anzeigen	2 bis 3 Tage	$289.00	Details
ABIN1590155	Human	Ziege	Unkonjugiert	ELISA, IHC, WB	100 μg	Anmelden zum Anzeigen	6 bis 7 Tage	$429.62	Details
ABIN3197928	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	200 μL	Anmelden zum Anzeigen	13 bis 14 Tage	$487.50	Details
ABIN3197929	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	200 μL	Anmelden zum Anzeigen	13 bis 14 Tage	$487.50	Details
ABIN1536128	Human	Kaninchen	Unkonjugiert	ELISA, WB	100 μg	Anmelden zum Anzeigen	2 bis 3 Tage	$302.50	Details
ABIN3181788	Human	Kaninchen	Unkonjugiert	ELISA, WB	100 μL	Anmelden zum Anzeigen	16 Days	$181.73	Details
ABIN1978154	Human	Ziege	Unkonjugiert	ELISA, IHC, IHC (p)	50 μg	Anmelden zum Anzeigen	7 bis 9 Tage	$484.00	Details
ABIN611363	Rind (Kuh)	Kaninchen	Unkonjugiert	WB	50 μg	Anmelden zum Anzeigen	7 bis 9 Tage	$551.83	Details
ABIN1804604	Human	Maus	Unkonjugiert	ELISA, IHC, IHC (p), WB	50 μL	Anmelden zum Anzeigen	7 bis 9 Tage	$639.83	Details

Weitere Produktkategorien zu Cathepsin C Antikörper

Weitere Antikörper gegen Cathepsin C Interaktionspartner

Human Cathepsin C (CTSC) Interaktionspartner

A compound mutation consisting of a large deletion and a nonsense mutation, which provides a new insight in the mutation type of CTSC gene.
CTSC gene missense mutation is responsible for Papillo- Lefevre syndrome in a Turkish family.
analysis of fluorescent substrates provides a detailed S' specificity study of cathepsin C
Mutation screening of the CTSC gene from the two patients revealed the presence of the same homozygous nonsense mutation in Papillon-Lefevre syndrome and Haim-Munk syndromes. Phenotypic variants of the same rare disease caused by mutations of the cathepsin C (CTSC) gene.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
CTSC was associated with albuminuria in type 2 diabetes patients.
Homozygous mutation 901G>A in exon 7 of CTSC gene is associated with Papillon-Lefevre syndrome.
Results identify a missense mutation in CTSC gene that segregate within a family with Papillon-Lefevre syndrome.
Papillon-Lefevre syndrome cause by homozygous nonsense mutation of cathepsin C gene.
CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.

Mouse (Murine) Cathepsin C (CTSC) Interaktionspartner

During the active remyelinating phase, both CysF knockdown (CysFKD) and microglial-selective CatC overexpression (CatCOE) showed a worsening of the demyelination in Plp (zeige C3 Antikörper)(4e/-) transgenic mice. Conversely, during the chronic demyelinating phase, CatC knockdown (CatCKD) ameliorated the demyelination. Our results suggest that the balance between CatC and CysF expression controls the demyelination and remyelination process.
Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.
Double immunofluorescence analysis showed that CTLA-2alpha was co-localized with cathepsin L (zeige CTSL1 Antikörper), cathepsin C, and TINAGL1 (zeige TINAGL1 Antikörper) in placenta.
CatC has a role in the selective tuning of innate and adaptive immune responses, relevant to a chronic immune disease, such as atherosclerosis.
Data indicate that all-trans retinoic acid (ATRA), which induces miR (zeige MLXIP Antikörper)-23a expression, decreases cathepsin C (CTSC) expression and granzyme B activity leading to impaired NK cell cytotoxicity.
These results establish that DPPI is a major determinant of survival following Klebsiella pneumoniae lung infection and suggest that the survival disadvantage in DPPI(+/+) mice is in part due to processing of surfactant protein D (zeige SFTPD Antikörper) by DPPI.
found no significant role for CtsC during mammary carcinogenesis but revealed squamous carcinogenesis to be functionally dependent on CtsC
Late stage cathepsin C, CXCL13 (zeige CXCL13 Antikörper) and Ki-67 (zeige MKI67 Antikörper) overexpression correlate with regional neuropathology in a bovine spongiform encephalopathy transgenic murine model.
Proinflammatory cytokines induce expression and release of cathepsin C in microglial cells during neuroinflammatory progression.
The production of IL-1beta (zeige IL1B Antikörper) by macrophages, neutrophils, and mast cells in vitro is dependent on caspase-1 (zeige CASP1 Antikörper) but not on cathepsin C.

Cathepsin C (CTSC) Antigen-Profil

Protein Überblick

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in immune/inflammatory cells. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor, and a residual portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Cathepsin C (CTSC) Antikörper

cathepsin C (CTSC) Antikörper
cathepsin C L homeolog (ctsc.L) Antikörper
cathepsin C (ctsc) Antikörper
cathepsin C (TP03_0357) Antikörper
cathepsin C (CMU_003360) Antikörper
cathepsin CPC1 (CPC1) Antikörper
cathepsin C (NAEGRDRAFT_80477) Antikörper
cathepsin C (NAEGRDRAFT_37577) Antikörper
cathepsin C (Ctsc) Antikörper
cathepsin C (Smp_183330) Antikörper

AI047818 Antikörper
CATC Antikörper
cb912 Antikörper
CPPI Antikörper
DPP-I Antikörper
DPP1 Antikörper
DPPI Antikörper
HMS Antikörper
ik:tdsubc_1h2 Antikörper
JP Antikörper
JPD Antikörper
MGC69126 Antikörper
MGC107782 Antikörper
PALS Antikörper
PDON1 Antikörper
PLS Antikörper
sb:cb146 Antikörper
wu:fb34g12 Antikörper
wu:fj58d01 Antikörper

Bezeichner auf Proteinebene für anti-Cathepsin C (CTSC) Antikörper

cathepsin J , dipeptidyl peptidase 1 , dipeptidyl peptidase I , dipeptidyl transferase , dipeptidyl-peptidase I , cathepsin C , dipeptidyl peptidase 1 isoform a preproprotein , DPPI , DPP-I , Dipeptidyl-peptidase 1 , dipeptidyl-peptidase 1 , dipeptidylpeptidase 1

GENE ID	SPEZIES
1075	Homo sapiens
380203	Xenopus laevis
407938	Xenopus (Silurana) tropicalis
419014	Gallus gallus
451469	Pan troglodytes
705320	Macaca mulatta
3500364	Theileria parva strain Muguga
6997925	Cryptosporidium muris RN66
7899372	Toxoplasma gondii ME49
8851692	Naegleria gruberi strain NEG-M
8855504	Naegleria gruberi strain NEG-M
100172530	Pongo abelii
13032	Mus musculus
25423	Rattus norvegicus
352958	Bos taurus
403458	Canis lupus familiaris
100101594	Oryctolagus cuniculus
100714387	Cavia porcellus
101112686	Ovis aries
8346758	Schistosoma mansoni
368704	Danio rerio

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