anti-Casein alpha S1 (CSN1S1) Antikörper

Human Casein alpha S1 (CSN1S1) Interaktionspartner

1. Serine-71 in alpha-S1 casein is phosphorylated in the breast milk.

2. Results suggest that autoimmunity to insulin can occur infrequently via cross-reactivity to food protein alpha casein.

3. Casein alpha s1 is expressed in human monocytes and stimulates expression of proinflammatory cytokine granulocyte-macrophage colony-stimulating factor (GM-CSF) via an immunomodulatory role beyond the nutritional function of CSN1S1 in milk.

4. alphas1-Casein may be a potential biomarker for early identification of BPH patients.

Mouse (Murine) Casein alpha S1 (CSN1S1) Interaktionspartner

1. The role of the milk protein alpha-casein by inactivating the corresponding gene in mice, was analysed.

Cow (Bovine) Casein alpha S1 (CSN1S1) Interaktionspartner

1. Identification of genomic regions associated with alphaS1-casein phosphorylation.

2. There were no associations between x genotype and fertility related traits in this study.

3. The results give insight in phosphorylation of alpha(S1)-CN-8P and alpha(S1)-CN-9P, which seem to be regulated by a different set of genes.

4. Report proteomic detection of bovine alpha-S1-casein in term and preterm human colostrum.

5. Data indicate that the pepsin-pancreatin digest of alphaS-Casein exhibited anxiolytic-like activity.

6. The genetic effects of thyroglobulin and casein alpha s1 alpha in the body fat distribution of cattle are reported.

7. Alpha-S2-casein was less effective at preventing fibril formation by modified kappa-casein, whereas alpha- and alpha-S1 casein were comparably potent inhibitors.

8. Single or multiple amino acid substitutions within IgE-binding epitopes result in reduced binding of milk-specific IgE antibodies. Critical amino acids should be evaluated with individual patient sera to determine B-cell-epitope heterogeneity.

9. determination of T cell reactive epitopes

10. EMSA analysis comparing allelic variants of a polymorphic AP-1 binding site in the promoter region of CSN1S1; specific and reduced protein binding of oligonucleotides containing the G variant of the CSN1S1-175bp binding site was shown

11. An isoelectrofocusing pattern was identified, which may result from a novel CSN1S1 variant, named CSN1S1*I, migrating at an intermediate position between CSN1S1*B and CSN1S1*C.

12. Substitution effects of paternal CSN2alpha (s1) allele versus CSN2 alpha(s2) allele on protein yield deviations (YDs) are significant, whereas their effects on milk and fat YDs are not.

Goat Casein alpha S1 (CSN1S1) Interaktionspartner

1. The alpha s1 casein genotype had a significant effect on milk yield, fat content and protein content.