CD68 Molecule Proteine (CD68)

CD68 encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. Zusätzlich bieten wir Ihnen CD68 Antikörper (706) und CD68 Kits (34) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CD68 12514 P31996
CD68 287435  
CD68 968 P34810
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Showing 10 out of 29 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
Details
HEK-293 Cells Human Fc Tag The purity of Human CD68 Fc Tag was determined by DTT-reduced (+) SDS-PAGE and staining overnight with Coomassie Blue. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$715.00
Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
$5,355.45
Details
Human Cells Human Fc Tag,His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$375.00
Details
HEK-293 Cells Human Fc Tag Human CD68, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 100 μg Anmelden zum Anzeigen 11 Days
$275.00
Details
Human Cells Ratte His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Baculovirus infected Insect Cells Human His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
Details
Hefe Maus His tag 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$578.60
Details
Escherichia coli (E. coli) Maus His-SUMO Tag 100 μg Anmelden zum Anzeigen 11 Days
$581.90
Details

CD68 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) , ,
, , ,
Rat (Rattus) ,
,
Human , , , , , ,
, , , ,

Weitere Proteine zu CD68 Molecule (CD68) Interaktionspartnern

Mouse (Murine) CD68 Molecule (CD68) Interaktionspartner

  1. Findings indicate that human CD68 and its mouse ortholog macrosialin located in the lysosomal membrane and share many structural similarities.

  2. Myeloid osteoclast precursors do not express CD68.

  3. CD68, a putative receptor for sporozoite invasion of Kupffer cells that acts as a gateway for malaria infection of the liver.

  4. Results showed that activated microglia in Alzheimer's disease-like mice showed two-step transition: a CD68-negative activated form at 6-9 months and a CD68-positive form from 12 months of age

  5. Statins promote the beneficial remodeling of plaques in diseased mouse arteries through the stimulation of the CCR7 (zeige CCR7 Proteine) / CD68 emigration pathway in macrophages

  6. These findings demonstrate a role for CD68 in the function of osteoclasts.

  7. CD68-null mononuclear phagocytes exhibited a trend toward enhanced antigen presentation to CD4+ T cells, indicating that CD68 may function to negatively regulate antigen uptake, loading, or major histocompatibility complex class II trafficking.

  8. Atherogenic diet-induced reduction in lipid levels of Reversa model mouse leads to decreased monocyte-derived CD68-positive cells in advanced atherosclerotic plaques and is associated with emigration of these cells from the atherosclerotic plaques.

  9. Macrosialin does not function as an oxLDL receptor on the cell surface.

  10. Data show that macrosialin (CD68), a macrophage-specific protein, is increased by aging in selected brain regions of male C57BL/6NNia mice.

Human CD68 Molecule (CD68) Interaktionspartner

  1. Combined detection of tumor-associated macrophages markers, CD68 and Sema4D (zeige SEMA4D Proteine), in gastric carcinoma tissue shows potential to predict the trend of gastric carcinoma progression.

  2. The study revealed that CD16 (zeige CD16 Proteine)-CD68-expressing macrophages appear to participate in ureteral neoplastic transformation.

  3. A combination of CD68/CD206 (zeige MRC1 Proteine) density and HBV-positivity improves further predictive value for post-operative recurrence of hepatocellular carcinoma (HCC (zeige FAM126A Proteine)) . Quantification of CD68/CD206 (zeige MRC1 Proteine) macrophages and their distribution can be exploited for better postsurgical management of HCC (zeige FAM126A Proteine) patients.

  4. Report CD68 over-expression in multinucleated giant cells and mononuclear cells in central and peripheral giant cell granuloma of jaw.

  5. This study shown the CD68 expression in Microglia and Astrocytes in stroke, Alzheimer's disease, and Lewy body dementia.

  6. The results of this study found that the expression levels of Cd68 and Atp5b (zeige ATP5B Proteine) were significantly correlated with the neurofibrillary tangle burden in the Alzheimer's Disease brain and with their cognition.

  7. Taken together, these results suggested that the changes, including ox-LDL/LDL ratio, CD68(+)/RANK(+) cells number, and the levels of RANKL (zeige TNFSF11 Proteine) and HMGB1 (zeige HMGB1 Proteine) in AS patients, favored osteoclastogenesis.

  8. High expression of CD68 is associated with nonalcoholic steatohepatitis.

  9. increased amount of CD68+TAM (zeige CCNA1 Proteine) in gaps of ductal tumor structures is protective against metastatic spread in regional lymph nodes.

  10. Most cases of histiocytic sarcoma expressed histiocytic markers CD68 (6 of 7 cases), CD163 (zeige CD163 Proteine) (5 of 5 cases), and PU.1 (3 of 4 cases).

CD68 Protein Überblick

Protein Überblick

This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

Genbezeichner und Symbole assoziert mit CD68 Molecule Proteine (CD68)

  • CD68 molecule (CD68)
  • CD68 antigen (Cd68)
  • Cd68 molecule (Cd68)
  • GP110 Protein
  • LAMP4 Protein
  • SCARD1 Protein

Bezeichner auf Proteinebene für CD68 Molecule Proteine (CD68)

macrosialin , CD68 antigen , macrophage antigen CD68 , scavenger receptor class D, member 1

GENE ID SPEZIES
100344094 Oryctolagus cuniculus
12514 Mus musculus
287435 Rattus norvegicus
968 Homo sapiens
504960 Bos taurus
101099002 Felis catus
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