anti-CD151 Molecule (Raph Blood Group) (CD151) Antikörper

Mouse (Murine) CD151 Molecule (Raph Blood Group) (CD151) Interaktionspartner

1. CD151 is a critical novel host factor of nuclear export signaling.

2. in complex with P2Y12 receptor contributes to thrombus growth and stability

3. Tetraspanin CD151 Is a Negative Regulator of FcepsilonRI-Mediated Mast Cell Activation

4. Integrin-associated CD151 represses mammary branching morphogenesis by controlling progenitor cell activities, extracellular matrix integrity and transcription program.

5. Study provide additional evidence that CD151 acts to enhance tumor formation initiated by a range of oncogenes.

6. We identify CD151 as a critical factor in tetradecanoylphorbol acetate-dependent skin carcinogenesis.

7. Loss of CD151 is associated with drug sensitivity in skin squamous cell carcinoma.

8. study provides strong evidence that CD151 collaborates with LB integrins (particularly alpha6beta4 and ErbB2 (and EGFR) receptors to regulate multiple signaling pathways, thereby driving mammary tumor onset, survival, and metastasis

9. CD151 importantly modulates podocyte function.

10. establish CD151 as a crucial modifier of integrin-mediated adhesion of podocytes to the GBM and show that blood pressure is an important factor in the initiation and progression of Cd151 knockout-induced nephropathy

11. CD151 maintains vascular stability by promoting endothelial cell adhesions, especially cell-cell adhesion, and confining cytoskeletal tension.

12. diminished metastasis in CD151-null host animals may be due to impaired tumor-endothelial interactions, with underlying defects in mouse lung endothelial cell extracellular matrix production.

13. CD151 controls Met-dependent neoplastic growth by enhancing receptor signaling through beta4 integrin-mediated pathways, independent of cell-substrate adhesion

14. CD151 may be involved in the interaction of platelets with the subendothelial matrix at sites of vascular damage [review]

15. CD151 plays a key role in selectively strengthening alpha6beta1 integrin-mediated adhesion to laminin-1

16. CD151-null mice show phenotypes in several different tissue types: a minor abnormality in hemostasis; keratinocytes migrate poorly in skin explant cultures; T lymphocytes are hyperproliferative in response to in vitro mitogenic stimulation.

17. CD151 is essential for normal platelet function and that disruption of CD151 induced a moderate outside-in integrin alpha(IIb)beta(3) signaling defect

18. CD151 plays a key role in strengthening alpha3beta1-mediated adhesion in podocytes.

19. CD151 modulates molecular organization of laminin-binding integrins, thereby supporting secondary (ie, after cell adhesion) functions of endothelial cells, which are needed for some types of pathologic angiogenesis

20. Demonstrate that promoting immobility through a CD151-specific metastasis blocking mAb prevents tumor cell dissemination by inhibiting intravasation without affecting primary tumor growth, tumor cell arrest, extravasation, or growth at the secondary site.

Human CD151 Molecule (Raph Blood Group) (CD151) Interaktionspartner

1. The expression of tetraspanins NET-6 and CD151 may indicate an alteration of their biological function during neoplastic transformation.

2. an involvement of CD151 in regulation of ErbB2/ErbB3 heterodimerization and its impact on cell response to Herceptin, is reported.

3. CD151 supports anti-cancer drug resistance independent of integrins.

4. CD151 promotes proliferation and migration of SK-NEP-1 cells through the GSK-3beta/P21/cyclinD signaling pathway in this study

5. Results provide evidence that bi-allelic loss-of-function mutations in CD151 underlie an autosomal recessive mechano-bullous disease with systemic features suggesting that CD151 as the 20th causative, EB-associated gene.

6. The expression levels of RNASEH2A, CDK1, and CD151 and their combination could predict the survival of renal cell carcinoma patients.

7. We conclude that LAMC1 mRNA acts as a trans regulator to stimulate CD151 expression by competing for miR-124 binding in hepatocellular carcinoma cells.

8. CD151 overexpression was associated with poor survival in human solid tumors. CD151 could be a valuable prognosis biomarker or a potential therapeutic target of solid tumors.

9. Levels of CD151 Gene Expression are Independently Associated with Survival in Chemoradiotherapy-Naive Patients

10. CD151 induces osteosarcoma metastasis likely by regulating cell function through adhesion signaling

11. These results elucidated that PIK3C2A mRNA acts as a miR-124 decoy to regulate CD151 and to affect hepatocellular carcinoma malignant phenotypes.

12. the tetraspanin CD151 contributes to survival of a subset of high-grade serous ovarian cancer cell lines.

13. CD151 in humans thus marks and enables hyperproliferative T cells.

14. Here, we demonstrate for the first time that the tetraspanin CD151 supports lymphocyte adhesion to liver endothelium. We show that CD151 is upregulated in chronic liver disease and hepatocellular carcinoma (HCC) and is regulated on endothelium by tissue remodeling and procarcinogenic factors.

15. Our data uncover a previously unknown mechanism for modulating human airway smooth muscle contraction, implicating CD151 as a determinant of airway hyper-responsiveness in vivo, likely through regulation of G protein-coupled receptor-induced calcium mobilization and protein kinase c signaling

16. Reciprocal fusion gene involving TSPAN4-CD151 is associated with infratentorial anaplastic ependymoma.

17. High CD151 expression is associated with hepatocellular carcinoma.

18. Eight and five of the nine samples were negative for cell adhesion molecule 1 and Osterix respectively. The other markers showed no statistical significance(CD151,ALP). osteoblastic differentiation can occur in carcinoma cells and that cell adhesion molecule 1 could be a useful marker for identifying this phenomenon in carcinoma tissues.

19. The findings suggest that, in contrast with previous models, the ligand-binding site of integrin alphaVbeta3, binds to the constant region (helices A and B) of the EC2 domain of CD9, CD81, and CD151 antigens.

20. High CD151 expression is associated with Human Cytomegalovirus Infection.