anti-Bromodomain Containing 7 (BRD7) Antikörper

BRD7 encodes a protein which is a member of the bromodomain-containing protein family. Zusätzlich bieten wir Ihnen BRD7 Proteine (6) und BRD7 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
BRD7 29117 Q9NPI1
BRD7 26992 O88665
BRD7 361374  
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Top anti-BRD7 Antikörper auf

Showing 10 out of 67 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-BRD7 Antibody Titration:  0.2-1 ug/ml  Positive Control:  Jurkat cell lysate BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat Host:  Rabbit  Target Name:  BRD7  Sample Type:  Jurkat  Lane A:  Primary Antibody  Lane B:  Primary Antibody + Blocking Peptide  Primary Antibody Concentration:  2.5ug/mL  Peptide Concentration:  2.0ug/mL  Lysate Quantity:  25ug/lane  Gel Concentration:  12%  BRD7 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Maus Kaninchen Unkonjugiert WB BRD7 Antibody (N-term) (ABIN657374) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the BRD7 antibody detected the BRD7 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of HeLa cells, using BRD7 antibody. Western blot analysis on HeLa cell lysate using BRD7 Antibody 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
Hund Kaninchen Unkonjugiert IHC, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with BRD7 antibody ABIN214730 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Anti-BRD7 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml. This image was taken for the unconjugated form of this product. Other forms ... 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: BRD7 Antibody [NBP1-28727] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml). 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of BRD7 using anti-BRD7 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: human SW620 whole cell lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-BRD7 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for BRD7 at approximately 90KD. The expected band size for BRD7 is at 74KD. IHC analysis of BRD7 using anti-BRD7 antibody . BRD7 was detected in paraffin-embedded section of human colon cancer tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-BRD7 Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using BRD7 antibody (ABIN5971285) at 1/1000 dilution. 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
Human Maus Biotin IP   100 μg Anmelden zum Anzeigen 7 bis 9 Tage

Am meisten referenzierte anti-BRD7 Antikörper

  1. Dog (Canine) Polyclonal BRD7 Primary Antibody für IHC, WB - ABIN2780896 : Zhou, Tan, Hershenson: Yersinia YopJ inhibits pro-inflammatory molecule expression in human bronchial epithelial cells. in Respiratory physiology & neurobiology 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen BRD7 Interaktionspartner

Human Bromodomain Containing 7 (BRD7) Interaktionspartner

  1. the transcriptional signature of low BRD7 expressing cells is associated with increased angiogenesis.

  2. our data indicated that BRD7 may serve as a tumor suppressor in hepatocellular carcinoma

  3. Results demonstrate a novel function of BRD7 in TGF-beta (zeige TGFB1 Antikörper) signaling. BRD7 interacts with the Smad (zeige SMAD1 Antikörper) tumor suppressor complex, and enhances both DNA-binding ability and transcriptional activity of Smads. BRD7 functions in growth inhibition and tumor suppression partly as a transcriptional co-activator of Smads.

  4. Overexpression of BRD7 inhibited cyclin D and myc (zeige MYC Antikörper) expression. Our findings are consistent with a tumor suppressor role for BRD7 in lung adenocarcinoma tumorigenesis.

  5. the expression of miR (zeige MLXIP Antikörper)-141 in BRD7-overexpressing NPC (zeige NPC1 Antikörper) cells could partially reverse the tumor suppressive effect of BRD7 on cell proliferation and tumor growth in vitro and in vivo.

  6. constructed a regulating network of BRD7 downstream genes, and this network suggests multiple feedback regulations of the pathways. Furthermore, we validated BIRC2 (zeige BIRC2 Antikörper), BIRC3 (zeige BIRC3 Antikörper), TXN2 (zeige TXN2 Antikörper), and NOTCH1 (zeige NOTCH1 Antikörper) genes as direct, functional BRD7 targets

  7. Propose that the balance between BRD7 function and Ras/Raf (zeige RAF1 Antikörper)/MEK (zeige MAP2K1 Antikörper)/ERK (zeige EPHB2 Antikörper) activity is important for determining the outcomes of HCV infection and HCC (zeige FAM126A Antikörper) development.

  8. Ectopic expression of BRD7 could significantly inhibit miR (zeige MLXIP Antikörper)-300-promoted proliferation, invasion and epithelial-mesenchymal transition in osteosarcoma.

  9. BRD7 promoter hypermethylation is an indicator of well differentiated oral squamous cell carcinomas.

  10. Data indicate that bromodomain-containing protein 7 (BRD7) was a direct target of microRNA-410 (miR (zeige MLXIP Antikörper)-410).

Mouse (Murine) Bromodomain Containing 7 (BRD7) Interaktionspartner

  1. A novel basis for understanding the molecular dynamics of glucose metabolism and the unique function of BRD7 in the regulation of glucose homeostasis.

  2. these findings suggest that BRD7 has an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-small ka, CyrillicB signaling pathway, which provides evidence to aid in understanding the therapeutic effects of BRD7 on inflammatory diseases

  3. Furthermore, Brd7 inhibition alters the phenotype of macrophages and promotes plaque instability, at least partly via STAT6 (zeige STAT6 Antikörper) signaling. Our data define a previously undescribed role of Brd7 in the development of atherosclerosis.

  4. Homozygous BRD7 knockout (KO) mice showed retardation in development.

  5. Homozygous knockout of BRD7 (BRD7(-/-)) resulted in complete male infertility and spermatogenesis defects, including deformed acrosomal formation, degenerative elongating spermatids and irregular head morphology in postmeiotic germ cells in the seminiferous epithelium, which led to the complete arrest of spermatogenesis at step 13.

  6. Results link BRD7 to medial prefrontal cortex synaptic plasticity regulation; knockout leads to impaired cognitive behavior accompanied by reduced synaptic related proteins expression and dendritic spines or branching in the medial prefrontal cortex

  7. BRD7 interacts with the regulatory subunits of phosphatidylinositol 3-kinase (PI3K) and increases the nuclear translocation of both p85alpha and p85beta and the spliced form of XBP1 (zeige XBP1 Antikörper) (XBP1s).

  8. TRIM24 (zeige TRIM24 Antikörper) regulates AR-mediated transcription in collaboration with TIP60 (zeige KAT5 Antikörper) and BRD7.

  9. BRD7 is a novel PBAF-specific SWI (zeige SMARCA1 Antikörper)/SNF (zeige SNRPA Antikörper) subunit that is required for target gene activation and repression in embryonic stem cells

BRD7 Antigen-Profil

Protein Überblick

This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit BRD7

  • bromodomain containing 7 L homeolog (brd7.L) Antikörper
  • bromodomain containing 7 (brd7) Antikörper
  • bromodomain containing 7 (BRD7) Antikörper
  • bromodomain containing 7 (Brd7) Antikörper
  • BP75 Antikörper
  • BRD7 Antikörper
  • CELTIX1 Antikörper
  • MGC79478 Antikörper
  • NAG4 Antikörper
  • Ptpn13ip Antikörper
  • wu:fc95f02 Antikörper
  • zgc:66347 Antikörper

Bezeichner auf Proteinebene für BRD7

bromodomain containing 7 , nuclear transcriptor-like protein , bromodomain-containing protein 7-like , bromodomain-containing protein 7 , 75 kDa bromodomain protein , protein CELTIX-1 , bromodomain protein 75 kDa , bromodomain-containing 7 , protein tyrosine phosphatase, non-receptor type 13 interacting protein

398590 Xenopus laevis
406675 Danio rerio
493370 Xenopus (Silurana) tropicalis
694850 Macaca mulatta
100404973 Callithrix jacchus
411112 Apis mellifera
29117 Homo sapiens
26992 Mus musculus
415730 Gallus gallus
478130 Canis lupus familiaris
526153 Bos taurus
361374 Rattus norvegicus
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