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binds the guanylate kinase domain of PSD-95/SAP90, may play a role in the post-synaptic membrane [RGD, Feb 2006]..
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Human Polyclonal BEGAIN Primary Antibody für ICC, IF - ABIN4283890
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
With the exception of associations of BEGAIN with severe and UBE3D with moderate chronic periodontitis (CP) , no other loci were associated with CP in ARIC or aggressive periodontitis in the German sample.
This study found in BEGAIN was most significant and also showed significant correlations with gene expression.
BEGAIN was highly localized at the synapse of inner lamina II in the spinal dorsal horn and that its expression was up-regulated after peripheral nerve injury in wild-type, but not in GluN2B (zeige GRIN2B Antikörper) Y1472F-KI, mice. Mechanical allodynia was significantly attenuated in BEGAIN-deficient mice, but no change was observed in terms of physiological threshold for mechanical stimuli.
A Begain transcript variant is preferentially expressed from the paternal allele.
binds the guanylate kinase domain of PSD-95/SAP90, may play a role in the post-synaptic membrane
brain-enriched guanylate kinase-associated homolog
, brain-enriched guanylate kinase-associated protein
, brain-enriched guanylate kinase-associated; brain-enriched guanylate kinase-associated protein
, brain-enriched guanylate kinase-associated protein 2B