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The protein encoded by BNIPL interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. Zusätzlich bieten wir Ihnen BNIPL Antikörper (18) und BNIPL Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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These results indicate the presence of two BNIP-S splicing variants as cellular regulators and that the BCH (zeige CHN2 ELISA Kits) domain of BNIP-Salpha confers a novel apoptotic function. The significance of this is discussed
interaction with cell proliferation-related proteins, MIF (zeige AMH ELISA Kits) and GFER (zeige GFER ELISA Kits)
BNIPL-2, a novel homologue of BNIP-2 (zeige BNIP2 ELISA Kits), interacts with Bcl-2 (zeige BCL2 ELISA Kits) and Cdc42GAP (zeige ARHGAP1 ELISA Kits) in apoptosis.
Data suggest that Bcl-2 (zeige BCL2 ELISA Kits)/adenovirus E1B (zeige BCKDHB ELISA Kits) 19 ku interacting protein 2-like (BNIPL-2) may regulate apoptosis through changes in the expression of genes associated with cell apoptosis, growth inhibition and cell proliferation.
p16INK4, IL-12 (zeige IL12A ELISA Kits), TRAIL & lymphotoxin beta (zeige LTB ELISA Kits) gene involved in growth suppression or cell apoptosis were up-regulated & PTEN was down-regulated by BNIPL-1;suggests that it might inhibit cell growth though cell cycle arrest &/or apoptotic cell death pathway(s)
The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
, bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein