anti-BCL2-Like 12 (Proline Rich) (BCL2L12) Antikörper

Human BCL2-Like 12 (Proline Rich) (BCL2L12) Interaktionspartner

1. Activation of PAR2 (zeige F2RL1 Antikörper) inhibits the expression of IL-10 (zeige IL10 Antikörper) in B cells, which can be reversed by treating B cells with Bcl2L12 shRNA-carrying liposomes.

2. BCL2L12 is a new prognostic biomarker for favorable outcome in diffuse large B-cell lymphoma patients on rituximab.

3. stress hormone cortisol suppresses p53 (zeige TP53 Antikörper) in hepatocellular carcinoma via enhancing Bcl2L12 expression

4. TNF-alpha (zeige TNF Antikörper) suppresses IL-10 (zeige IL10 Antikörper) in peripheral B cells via up-regulating Bcl2L12 in patients with ulcerative colitis.

5. miR (zeige MLXIP Antikörper)-125a-5p inhibits cell proliferation and induces apoptosis in colon cancer cells via targeting BCL2 (zeige BCL2 Antikörper), BCL2L12 and Mcl-1 (zeige MCL1 Antikörper).

6. Identify 50 novel BCL2L12 splice variants in human tumor cell lines.

7. Results show that high Bcl2L12 mRNA expression was associated with the high-grade breast cancer and triple-negative (TNBC) subtype. Also, the interplay between Bcl2L12 and its variant may be associated with high lymph node metastasis in non-TNBC tumors.

8. CD82 (zeige CD82 Antikörper) regulated BCL2L12 expression via STAT5A (zeige STAT5A Antikörper) and AKT (zeige AKT1 Antikörper) signaling and stimulated proliferation and engrafting of leukemia cells.

9. Bcl2L12 retains a BH3-like domain, which is important for its anti-apoptotic property.

10. Data indicate that BCL2-like 12 (proline rich) protein (zeige C4BPA Antikörper) BCL2L12 mRNA levels can distinguish women with breast cancer from healthy controls.

Mouse (Murine) BCL2-Like 12 (Proline Rich) (BCL2L12) Interaktionspartner

1. nuclear Bcl2L12 physically and functionally interacts with the p53 tumor suppressor (zeige TP53 Antikörper)

2. Data show that apoptotic defect in Irf3 (zeige IRF3 Antikörper)(-/-)Bcl2l12(-/-) MEFs was rescued by the ectopic expression of Bcl2L12, but not IRF3 (zeige IRF3 Antikörper).