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ASAP2 Proteine

ASAP2 encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain.

4 Treffer:

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-1006) protein (His tag) Protein

ASAP2 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3089284
$15,464.90
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 70 Werktagen

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-958) protein (His tag) Protein

ASAP2 Spezies: Maus Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. Crys, ELISA, SDS, WB
Produktnummer ABIN3135911
$15,464.90
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
1 mg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 70 Werktagen

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 1-1006) protein (GST tag) Protein

ASAP2 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
Produktnummer ABIN1345787
$574.29
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
10 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen

ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2) (AA 909-1006) protein (GST tag) Protein

ASAP2 Spezies: Human Wirt: Wheat germ Recombinant AA, AP, ELISA, WB
Produktnummer ABIN1345789
$574.29
Zzgl. Versandkosten $45.00 und $24.00 Trockeneis
10 μg (More quantities available)
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 11 bis 12 Werktagen
  • Typ Protein
    • Protein
  • Target ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
    • ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 2 (ASAP2)
    • Hemagglutinin (HA)
    • Ribosome Binding Factor A (RBFA)
    • Tumor Necrosis Factor alpha (TNF)
    • S-Adenosyl-Methionine Synthase (METK)
    • Interleukin 6 (IL6)
    • Interferon gamma (IFNG)
    • Hemoglobin beta (HBB)
    • Triosephosphate Isomerase 1 (TPI1)
    • Thymidylate Kinase (Tmk)
    • Interleukin 4 (IL4)
    • Interleukin 1, beta (IL1B)
    • Interleukin 2 (IL2)
    • Uracil-DNA Glycosylase (UNG)
    • Fibroblast Growth Factor 2 (Basic) (FGF2)
    • Lipoyl synthase lipA
    • Growth Hormone 1 (GH1)
    • Interleukin 10 (IL10)
    • KIT Ligand (KITLG)
    • Malate Dehydrogenase (MDH)
    • Insulin-Like Growth Factor 1 (IGF1)
    • Epidermal Growth Factor (EGF)
    • Interleukin 8 (IL8)
    • Leptin (LEP)
    • Interleukin 3 (IL-3)
    • Myoglobin (MB)
    • Queuine tRNA-Ribosyltransferase 1 (QTRT1)
    • Hemoglobin, alpha 1 (HBA1)
    • serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1 (SERPINE1)
    • phosphatidylserine Decarboxylase (PISD)
    • Interleukin 1 alpha (IL1A)
    • CD40 Ligand (CD40LG)
    • Prolactin (PRL)
    • Interleukin 13 (IL13)
    • Vascular Endothelial Growth Factor A (VEGFA)
    • Chemokine (C-X-C Motif) Ligand 12 (CXCL12)
    • Albumin (ALB)
    • Aspartate Carbamoyltransferase (PYRB)
    • Phosphoglucosamine Mutase (GLMM)
    • Porphobilinogen Deaminase (HEMC)
    • Interleukin 15 (IL15)
    • Phenylalanyl-tRNA Synthetase, alpha Subunit (FARSA)
    • beta-2-Microglobulin (B2M)
    • Chemokine (C-C Motif) Ligand 2 (CCL2)
    • Gp120
    • Interleukin 33 (IL33)
    • SARS-CoV-2 Spike S1
    • Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2)
    • Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic (CMPK1)
    • Fibroblast Growth Factor 1 (Acidic) (FGF1)
    • Adiponectin (ADIPOQ)
  • Anwendung
    • ELISA
    • Western Blotting (WB)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • SDS-PAGE (SDS)
    • Crystallization (Crys)
  • Reaktivität
    • Human
    • Maus
  • Abbildungen verfügbar
  • Wirt
    • Insektenzellen
    • Wheat germ
  • Bindungsspezifität
    • AA 1-1006
    • AA 1-958
    • AA 909-1006
  • Konjugat
    • Unkonjugiert
    • GST tag
    • His tag
  • Protein-Typ
    • Recombinant
  • Format
    • Liquid

ASAP2 Protein Überblick

Protein Überblick

This gene encodes a multidomain protein containing an N-terminal alpha-helical region with a coiled-coil motif, followed by a pleckstrin homology (PH) domain, an Arf-GAP domain, an ankyrin homology region, a proline-rich region, and a C-terminal Src homology 3 (SH3) domain. The protein localizes in the Golgi apparatus and at the plasma membrane, where it colocalizes with protein tyrosine kinase 2-beta (PYK2). The encoded protein forms a stable complex with PYK2 in vivo. This interaction appears to be mediated by binding of its SH3 domain to the C-terminal proline-rich domain of PYK2. The encoded protein is tyrosine phosphorylated by activated PYK2. It has catalytic activity for class I and II ArfGAPs in vitro, and can bind the class III Arf ARF6 without immediate GAP activity. The encoded protein is believed to function as an ARF GAP that controls ARF-mediated vesicle budding when recruited to Golgi membranes. In addition, it functions as a substrate and downstream target for PYK2 and SRC, a pathway that may be involved in the regulation of vesicular transport. Multiple transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit ASAP2

  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (ASAP2) Antikörper
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 L homeolog (asap2.L) Antikörper
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1b (asap1b) Antikörper
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (asap2) Antikörper
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Asap2) Antikörper
  • 6530401G17Rik Antikörper
  • AMAP2 Antikörper
  • asap2 Antikörper
  • CENTB3 Antikörper
  • Ddef2 Antikörper
  • Gm592 Antikörper
  • Gm1523 Antikörper
  • PAG3 Antikörper
  • PAP Antikörper
  • Pap-alpha Antikörper
  • SHAG1 Antikörper
  • si:dkey-37o8.2 Antikörper

Bezeichner auf Proteinebene für ASAP2

development and differentiation enhancing factor 2 , development- and differentiation-enhancing factor 2 , ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 , asap1 , PYK2 C terminus-associated protein , arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 , centaurin, beta 3 , development and differentiation-enhancing factor 2 , paxillin-associated protein with ARF GAP activity 3 , pyk2 C-terminus-associated protein

GENE ID SPEZIES
768599 Gallus gallus
100072516 Equus caballus
431962 Xenopus laevis
459014 Pan troglodytes
475659 Canis lupus familiaris
565859 Danio rerio
618009 Bos taurus
699774 Macaca mulatta
100411588 Callithrix jacchus
100440164 Pongo abelii
100548947 Meleagris gallopavo
100560107 Anolis carolinensis
100604148 Nomascus leucogenys
8853 Homo sapiens
211914 Mus musculus
362719 Rattus norvegicus

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