anti-Amyloid beta 40 (Abeta 40) Antikörper

Abeta 40 encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Zusätzlich bieten wir Ihnen Amyloid beta 40 Kits (60) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Abeta 40 351 P05067
Abeta 40    
Abeta 40    
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Top anti-Amyloid beta 40 Antikörper auf antikoerper-online.de

Showing 10 out of 29 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western Blot: Abeta 40 Antibody [NBP1-44047] - 1-40(lane 1) and 1-42 (lane 2) ABeta peptides were run on a 16.5% TRIS/tricine gel and transferred to PVDF membrane. The peptide concentration was approximately 0.5ng/lane. The blot was incubated with affinity purified AB40 antibody at 1ug/ml, followed by an oat and rabbit -HRP antibody at 1:40,000 and developed using a standard chemiluninescence method. A single band is present only in lane 1 which contains the ABeta 1-40 peptide and no signal is found in lane 2 which contains the ABeta 1-42 peptide. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$587.60
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and a commercially available monoclonal anti-Abeta antibody. 50 μg Anmelden zum Anzeigen 5 bis 6 Tage
$497.20
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: Abeta 40 Antibody [ABIN152565] - Detection of Abeta 40 on 5 ng of peptide per lane using ABIN152565. Lane 1: Abeta 40, lane 2: Abeta 42, Lane 3: Abeta 40 and 42 mix. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$446.35
Details
Human Maus Unkonjugiert DB, IHC, ELISA   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$280.57
Details
Maus Kaninchen Unkonjugiert IHC 200 μL Anmelden zum Anzeigen 12 bis 14 Tage
$438.90
Details
Human Kaninchen Unkonjugiert IHC, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and anti-Abeta (Cat. No. 218 111, dilution: 1 : 1000). 200 μL Anmelden zum Anzeigen 5 bis 6 Tage
$385.33
Details
Human Kaninchen Unkonjugiert FM, IHC, ELISA, WB   50 μg Anmelden zum Anzeigen 5 bis 7 Tage
$598.50
Details
Human Maus Unkonjugiert IC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$968.00
Details
Maus Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$545.42
Details
Human Kaninchen Biotin DB, RIA, ELISA, WB   25 μg Anmelden zum Anzeigen 16 Days
$784.14
Details

Am meisten referenzierte anti-Amyloid beta 40 Antikörper

  1. Human Polyclonal Abeta 40 Primary Antibody für ELISA, ICC - ABIN4277269 : Esler, Stimson, Fishman, Ghilardi, Vinters, Mantyh, Maggio: Stereochemical specificity of Alzheimer's disease beta-peptide assembly. in Biopolymers 1999 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Abeta 40 Primary Antibody für ELISA, WB - ABIN534376 : Johnson, Lapadat: Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. in Science (New York, N.Y.) 2002 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal Abeta 40 Primary Antibody für IHC, ELISA - ABIN1742443 : Christensen, Huettenrauch, Mitkovski, Pradier, Wirths: Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal A? accumulation. in Frontiers in aging neuroscience 2014 (PubMed)

  4. Human Polyclonal Abeta 40 Primary Antibody für ICC, IF - ABIN152565 : Pradines, Hernandez-Rapp, Villa-Diaz, Dakowski, Ardila-Osorio, Haik, Schneider, Launay, Kellermann, Torres, Mouillet-Richard: Pathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearance. in Cell death & disease 2013 (PubMed)

Weitere Antikörper gegen Amyloid beta 40 Interaktionspartner

Human Amyloid beta 40 (Abeta 40) Interaktionspartner

  1. The neuronal specific alpha3 (alpha3)-subunit of the plasma membrane enzyme Na, K-ATPase (NKA) is a new binding partner of sAPPalpha.

  2. Aggregation processes of ABETA on living cells and cytotoxic events were monitored by fluorescence techniques. ABETA formed amyloids after forming oligomers composed of approximately 10 ABETA molecules. The formation of amyloids was necessary to activate apoptotic caspase-3 and reduce the ability of the cell to proliferate; this indicated that amyloid formation is a key event in ABETA-induced cytotoxicity.

  3. esults suggest that P-gp plays important role in mediating rivastigmine non-cholinergic beneficial effects, including Abeta brain load reduction, neuroprotective and anti-inflammatory effects in the AD mouse models.

  4. Immature intracellular aggregates are more toxic than mature fibrillar ABETA(1-42).

  5. Downregulation of C9orf72 in non-neuronal human cells overexpressing amyloid-beta protein precursor (AbetaPP) resulted in increased levels of secreted AbetaPP fragments and Abeta, while levels of AbetaPP or its C-terminal fragments (CTFs) remained unchanged. In neuronal cells, AbetaPP and C83 CTF levels were decreased upon C9orf72 knockdown, but those of secreted AbetaPP fragments or Abeta remained unchanged.

  6. N-terminal mutations can affect Abeta fibril and oligomer formation, despite lying outside the core amyloid region of Abeta. Of the three factors that may influence Abeta-mediated toxicity (primary structure of Abeta, assembly structure and cellular responses), results suggest that it is more the assembly structure that correlates with effects on cell viability.

  7. The Swedish variant was a more potent co-activator of Wnt-PCP signalling than wild-type APP and, unlike wild-type APP, which co-activates Wnt beta-catenin signalling, APPSwe suppressed this branch of Wnt.

  8. Among hip fracture patients, 88.6% of the cognitively normal (Clinical Dementia Rating-CDR 0; n = 70) and 98.8% with mild cognitive impairment (CDR 0.5; n = 81) fell in the abnormal biomarker categories by CSF Abeta42/40 ratio, p-tau, and t-tau measures.

  9. FNDC5 significantly affects beta-cleavage of APP via the interaction with APP.

  10. uncovered for the first time a phenomenon of chaperone antagonism on BACE1-mediated Abeta42 generation.

  11. This study investigated the assembly mechanisms of dimeric ABETA 16-22 and found that the fibril formation rate is predominantly controlled by the total beta-strand content.

  12. Data suggest that the substitution of alanine by valine at position 2 of the amyloidogenic peptide affect the lateral interactions between fibrils, promoting a more compact, aligned and uniform structure which explains its aggressiveness in homozygous carriers and its prophylactic effect in heterozygous carriers.

  13. Solution NMR allowed us to define the secondary structure of this Abeta dimer, which shows interlocking contacts between C-terminal peptide strands. Thus, we present a novel Abeta oligomer that resists conversion to fibrils and remains stable for more than one year.

  14. Data suggest that antiinflammatory agents, non steroidal (NSAIDs) bind to amyloid beta (Abeta) protein leading to the blockage of hydrophobic site which might prevent incoming Abeta molecules from extending the fibril.

  15. Findings suggest that the polymorphisms of amyloid-beta (Abeta) fibril structures are caused by differences in the surrounding ionic environment.

  16. Young healthy adults carrying APOE epsilon4 and APP/presenilin-1/2 displayed different hippocampus functional connectivity patterns

  17. X-box binding protein 1 overexpression at an early stage reversed Abeta-induced early death without affecting learning performance in the Abeta42 transgenic flies. PERK activation was determined to only enhance Abeta-induced learning deficits.

  18. data suggests that the hydrophobic interactions between beta-casein and Abeta1-42 play an important role in the burial of the hydrophobic part of the Abeta1-42.

  19. APP-Knockout astrocytes have reduced cholesterol and elevated levels of sterol regulatory element-binding protein (SREBP) target gene transcripts and proteins, which were both downstream consequences of reduced lipoprotein endocytosis.

  20. Identified TMEM30A as a candidate partner for beta-carboxyl-terminal fragment (betaCTF) of amyloid-beta precursor protein (APP). TMEM30A physically interacts with betaCTF in endosomes and may impair vesicular traffic, leading to abnormally enlarged endosomes. Data suggested that TMEM30A is involved in betaCTF-dependent endosome abnormalities that are related to Abeta overproduction

Amyloid beta 40 (Abeta 40) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Abeta 40

  • amyloid beta precursor protein (APP) Antikörper
  • AAA Antikörper
  • ABETA Antikörper
  • ABPP Antikörper
  • AD1 Antikörper
  • APPI Antikörper
  • CTFgamma Antikörper
  • CVAP Antikörper
  • PN-II Antikörper
  • PN2 Antikörper

Bezeichner auf Proteinebene für Abeta 40

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II

GENE ID SPEZIES
351 Homo sapiens
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