anti-Amyloid beta 40 (Abeta 40) Antikörper

Abeta 40 encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Zusätzlich bieten wir Ihnen Amyloid beta 40 Kits (56) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Abeta 40 351 P05067
Abeta 40    
Abeta 40    
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Top anti-Amyloid beta 40 Antikörper auf antikoerper-online.de

Showing 10 out of 23 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western Blot: Abeta 40 Antibody [NBP1-44047] - 1-40(lane 1) and 1-42 (lane 2) ABeta peptides were run on a 16.5% TRIS/tricine gel and transferred to PVDF membrane. The peptide concentration was approximately 0.5ng/lane. The blot was incubated with affinity purified AB40 antibody at 1ug/ml, followed by an oat and rabbit -HRP antibody at 1:40,000 and developed using a standard chemiluninescence method. A single band is present only in lane 1 which contains the ABeta 1-40 peptide and no signal is found in lane 2 which contains the ABeta 1-42 peptide. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and a commercially available monoclonal anti-Abeta antibody. 50 μg Anmelden zum Anzeigen 5 bis 6 Tage
$506.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: Abeta 40 Antibody [ABIN152565] - Detection of Abeta 40 on 5 ng of peptide per lane using ABIN152565. Lane 1: Abeta 40, lane 2: Abeta 42, Lane 3: Abeta 40 and 42 mix. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Maus Unkonjugiert DB, IHC, ELISA   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$257.40
Details
Human Kaninchen Unkonjugiert IHC, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and anti-Abeta (Cat. No. 218 111, dilution: 1 : 1000). 200 μL Anmelden zum Anzeigen 5 bis 6 Tage
$392.15
Details
Human Kaninchen Unkonjugiert FM, IHC, ELISA, WB   50 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details
Human Maus Unkonjugiert IC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$947.57
Details
Maus Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$555.07
Details
Human Kaninchen Biotin DB, RIA, ELISA, WB   25 μg Anmelden zum Anzeigen 16 Days
$784.14
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$787.29
Details

Abeta 40 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)
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Mouse (Murine)
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Am meisten referenzierte anti-Amyloid beta 40 Antikörper

  1. Human Polyclonal Abeta 40 Primary Antibody für ELISA, ICC - ABIN4277269 : Esler, Stimson, Fishman, Ghilardi, Vinters, Mantyh, Maggio: Stereochemical specificity of Alzheimer's disease beta-peptide assembly. in Biopolymers 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Abeta 40 Primary Antibody für ICC, IF - ABIN152565 : Pradines, Hernandez-Rapp, Villa-Diaz, Dakowski, Ardila-Osorio, Haik, Schneider, Launay, Kellermann, Torres, Mouillet-Richard: Pathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearance. in Cell death & disease 2013 (PubMed)

  3. Human Polyclonal Abeta 40 Primary Antibody für IHC, ELISA - ABIN1742443 : Christensen, Huettenrauch, Mitkovski, Pradier, Wirths: Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal A? accumulation. in Frontiers in aging neuroscience 2014 (PubMed)

Weitere Antikörper gegen Amyloid beta 40 Interaktionspartner

Human Amyloid beta 40 (Abeta 40) Interaktionspartner

  1. Taken together, these results suggest that ApoE4 enhances Abeta (zeige APP Antikörper) inhibition of insulin (zeige INS Antikörper)-stimulated AMPA (zeige GRIA3 Antikörper) receptor function, which accelerates memory impairment in ApoE4xAPP mice.

  2. The authors found that as already shown for oligomeric Abeta (zeige APP Antikörper), also oligomeric Tau can bind to amyloid precursor protein (APP (zeige APP Antikörper)). Moreover, efficient intra-neuronal uptake of oligomeric Abeta (zeige APP Antikörper) and oligomeric Tau requires expression of APP (zeige APP Antikörper).

  3. Recombinant mutant KPI(R13I) domain of ABPP (zeige APP Antikörper) was ineffective in the inhibition of pro-thrombotic proteinases and did not inhibit the clotting of plasma in vitro.

  4. Analysis of biochemical fractions of Alzheimer's disease brain extract indicate that the seeding-activity correlated with the presence of ABETA (zeige APP Antikörper) peptide and ABETA (zeige APP Antikörper)-derived aggregates. In vitro-formed fibrils were also active but their activity was low and depending on the fibril structure and conditions of fibril formation.

  5. A comprehensive understanding of the still undefined contribution of Abeta (zeige APP Antikörper) truncations to the disease pathogenesis and their potential as novel therapeutic targets.

  6. The amyloid hypothesis proposes that Alzheimer's Disease is caused by altered beta-amyloid precursor protein expression or APP (zeige APP Antikörper)-mutation-induced Ab aggregation, following an imbalance between Ab production and Ab clearance.

  7. Phosphorylation of amyloid precursor protein by mutant LRRK2 promotes AICD activity and neurotoxicity in Parkinson's disease.

  8. Mass spectrometry analysis of APP (zeige APP Antikörper) intracellular domains revealed differential processing of APP (zeige APP Antikörper)-C83, APP (zeige APP Antikörper)-C89, and APP (zeige APP Antikörper)-C99 by gamma-secretase already at the epsilon-cleavage stage. This mechanistic insight could aid in developing substrate-targeted modulators of APP (zeige APP Antikörper)-C99 processing to specifically lower the Abeta42:Abeta40 ratio without compromising gamma-secretase function.

  9. enzymes known to act in other metabolic pathways, such as meprin beta (zeige MEP1B Antikörper), have been found to cleave APP (zeige APP Antikörper) to yield products known to participate in AD pathologies. This review provides an overview of current knowledge of conventional and novel APP (zeige APP Antikörper) processing.

  10. study provides molecular insights into the design of amyloidogenic inhibitors to cure various neurodegenerative and amyloid-associated diseases, as NABi would regulate aggregation of other toxic beta-sheet proteins other than Abeta (zeige APP Antikörper).

Amyloid beta 40 (Abeta 40) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Abeta 40

  • amyloid beta precursor protein (APP) Antikörper
  • AAA Antikörper
  • ABETA Antikörper
  • ABPP Antikörper
  • AD1 Antikörper
  • APPI Antikörper
  • CTFgamma Antikörper
  • CVAP Antikörper
  • PN-II Antikörper
  • PN2 Antikörper

Bezeichner auf Proteinebene für Abeta 40

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II

GENE ID SPEZIES
351 Homo sapiens
Ausgewählte Anbieter für anti-Amyloid beta 40 (Abeta 40) Antikörper
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