anti-Amyloid beta 40 (Abeta 40) Antikörper

Abeta 40 encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Zusätzlich bieten wir Ihnen Amyloid beta 40 Kits (53) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
Abeta 40 351 P05067
Abeta 40    
Abeta 40    
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Top anti-Amyloid beta 40 Antikörper auf antikoerper-online.de

Showing 10 out of 23 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ICC, IF, IP, WB Western Blot: Abeta 40 Antibody [ABIN152565] - Detection of Abeta 40 on 5 ng of peptide per lane using ABIN152565. Lane 1: Abeta 40, lane 2: Abeta 42, Lane 3: Abeta 40 and 42 mix. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western Blot: Abeta 40 Antibody [NBP1-44047] - 1-40(lane 1) and 1-42 (lane 2) ABeta peptides were run on a 16.5% TRIS/tricine gel and transferred to PVDF membrane. The peptide concentration was approximately 0.5ng/lane. The blot was incubated with affinity purified AB40 antibody at 1ug/ml, followed by an oat and rabbit -HRP antibody at 1:40,000 and developed using a standard chemiluninescence method. A single band is present only in lane 1 which contains the ABeta 1-40 peptide and no signal is found in lane 2 which contains the ABeta 1-42 peptide. 0.05 mg Anmelden zum Anzeigen 7 bis 9 Tage
$585.06
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and a commercially available monoclonal anti-Abeta antibody. 50 μg Anmelden zum Anzeigen 5 bis 6 Tage
$506.00
Details
Human Maus Unkonjugiert DB, IHC, ELISA   100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$257.40
Details
Human Kaninchen Unkonjugiert IHC, WB Detection of synthetic Abeta 1-38, 1-40 and 1-42 with anti-Abeta 40 (dilution 1 : 1000) and anti-Abeta (Cat. No. 218 111, dilution: 1 : 1000). 200 μL Anmelden zum Anzeigen 5 bis 6 Tage
$392.15
Details
Human Kaninchen Unkonjugiert FM, IHC, ELISA, WB   50 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details
Human Maus Unkonjugiert IC, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$947.57
Details
Maus Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 6 bis 7 Tage
$555.07
Details
Human Kaninchen Biotin DB, RIA, ELISA, WB   25 μg Anmelden zum Anzeigen 16 Days
$784.14
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$888.86
Details

Abeta 40 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus)
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Mouse (Murine)
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Am meisten referenzierte anti-Amyloid beta 40 Antikörper

  1. Human Polyclonal Abeta 40 Primary Antibody für ELISA, ICC - ABIN4277269 : Esler, Stimson, Fishman, Ghilardi, Vinters, Mantyh, Maggio: Stereochemical specificity of Alzheimer's disease beta-peptide assembly. in Biopolymers 1999 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal Abeta 40 Primary Antibody für ICC, IF - ABIN152565 : Pradines, Hernandez-Rapp, Villa-Diaz, Dakowski, Ardila-Osorio, Haik, Schneider, Launay, Kellermann, Torres, Mouillet-Richard: Pathogenic prions deviate PrP(C) signaling in neuronal cells and impair A-beta clearance. in Cell death & disease 2013 (PubMed)

  3. Human Polyclonal Abeta 40 Primary Antibody für IHC, ELISA - ABIN1742443 : Christensen, Huettenrauch, Mitkovski, Pradier, Wirths: Axonal degeneration in an Alzheimer mouse model is PS1 gene dose dependent and linked to intraneuronal A? accumulation. in Frontiers in aging neuroscience 2014 (PubMed)

Weitere Antikörper gegen Amyloid beta 40 Interaktionspartner

Human Amyloid beta 40 (Abeta 40) Interaktionspartner

  1. elevated levels of plasma homocysteine /homocysteine thiolactone contribute to AD pathology via the Abeta (zeige APP Antikörper)-fibrin(ogen) interaction

  2. Overexpression of human APP (zeige APP Antikörper) in mice reduce cortical free cholesterol under normal diet and HFD.

  3. The authors show that APP (zeige APP Antikörper) can physically interact with KCC2 (zeige SLC12A5 Antikörper), a neuron-specific K(+)-Cl(-) cotransporter (zeige SLC12A4 Antikörper) that is essential for Cl(-) homeostasis and fast GABAergic inhibition.

  4. beta-amyloid interacts with fibrinogen and factor XII (zeige F12 Antikörper). These interactions can lead to increased clotting, abnormal clot (zeige TXNDC17 Antikörper) formation, persistent fibrin deposition, and generation of proinflammatory molecules.

  5. Abeta (zeige APP Antikörper) activates FXII (zeige F12 Antikörper), resulting in FXI (zeige F11 Antikörper) activation and thrombin (zeige F2 Antikörper) generation in human plasma, thereby establishing Abeta (zeige APP Antikörper) as a possible driver of prothrombotic states

  6. Data suggest that aggregates of amyloid beta(1-40) induce excessive generation of reactive oxygen species, MAPK (zeige MAPK1 Antikörper)/NFkappaB (zeige NFKB1 Antikörper) signaling activation, and NLRP3 (zeige NLRP3 Antikörper) inflammasome activation in retinal pigment epithelial cells mimicking changes seen in age-related macular degeneration; this mechanism is dependent on NADPH oxidase (zeige NOX1 Antikörper).

  7. These results demonstrate a stage-dependent plasma Abeta (zeige APP Antikörper) increase that is augmented by loss of glomerulotubular integrity, low body weight, and inflammation, demonstrating a multifaceted role of renal dysfunction in Abeta (zeige APP Antikörper) retention.

  8. Combining a murine APP (zeige APP Antikörper)-deficient and a human APP (zeige APP Antikörper)-transgenic strain, we were able to analyse the progression of the cortical amyloidosis independent of the murine variant. The lack of endogenous mAPP (zeige XPNPEP2 Antikörper) resulted in accelerated deposition and, thus, increased number of senile plaques and higher levels of aggregated hAbeta.

  9. APP levels then decrease progressively as a function of age in close relationship with the gradual normalization of FMRP and hnRNP C levels.

  10. In Alzheimer's Disease brain, amyloid Beta-protein binds to synapses and requires the expression of amyloid precursor protein (zeige APP Antikörper) to disrupt synaptic activity.

Amyloid beta 40 (Abeta 40) Antigen-Profil

Protein Überblick

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit Abeta 40

  • amyloid beta precursor protein (APP) Antikörper
  • AAA Antikörper
  • ABETA Antikörper
  • ABPP Antikörper
  • AD1 Antikörper
  • APPI Antikörper
  • CTFgamma Antikörper
  • CVAP Antikörper
  • PN-II Antikörper
  • PN2 Antikörper

Bezeichner auf Proteinebene für Abeta 40

alzheimer disease amyloid protein , amyloid beta A4 protein , beta-amyloid peptide , cerebral vascular amyloid peptide , peptidase nexin-II , preA4 , protease nexin-II

GENE ID SPEZIES
351 Homo sapiens
Ausgewählte Anbieter für anti-Amyloid beta 40 (Abeta 40) Antikörper
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