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AKR1B10 encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. Zusätzlich bieten wir Ihnen Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Proteine (11) und Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) Kits (7) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 82 products:
Human Monoclonal AKR1B10 Primary Antibody für IF, IHC (p) - ABIN566074
Bains, Grigliatti, Reid, Riggs: Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin. in The Journal of pharmacology and experimental therapeutics 2010
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Human Polyclonal AKR1B10 Primary Antibody für ELISA, WB - ABIN566073
Loeffler-Ragg, Mueller, Gamerith, Auer, Skvortsov, Sarg, Skvortsova, Schmitz, Martin, Krugmann, Alakus, Maser, Menzel, Hilbe, Lindner, Schmid, Zwierzina: Proteomic identification of aldo-keto reductase AKR1B10 induction after treatment of colorectal cancer cells with the proteasome inhibitor bortezomib. in Molecular cancer therapeutics 2009
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Human Polyclonal AKR1B10 Primary Antibody für ELISA, WB - ABIN449362
Tammali, Ramana, Singhal, Awasthi, Srivastava: Aldose reductase regulates growth factor-induced cyclooxygenase-2 expression and prostaglandin E2 production in human colon cancer cells. in Cancer research 2006
Cow (Bovine) Polyclonal AKR1B10 Primary Antibody für WB - ABIN2775474
Lee, Paek, Kang, Jang, Kim, Kang, Kim, Lee, Lee, Chang, Nishinaka, Seo: Involvement of nuclear factor kappaB in up-regulation of aldose reductase gene expression by 12-O-tetradecanoylphorbol-13-acetate in HeLa cells. in The international journal of biochemistry & cell biology 2005
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These data suggest that AKR1B10 promotes breast cancer metastasis
Several antioxidant response elements-like sequences in the 5'-flanking region up to -3282 bp of the AKR1B10 gene plays an important role in AKR1B10 gene regulation by various Nrf2 (zeige GABPA Antikörper)-mediating stimuli.
This study presents novel evidence that AKR1B10 protects colon cells from DNA damage induced by electrophilic carbonyl compounds.
the highly efficient, retinaldehyde-specific aldo-keto reductase enzyme AKR1B10 is up-regulated in keloid epidermis(KE) and its induced overexpression in normal skin keratinocytes affects the classical RA pathway, recreating KE expression patterns
Data suggest that expression of STAR (steroidogenic acute regulatory protein (zeige STAR Antikörper)) and AKR1B10 (aldo-keto reductase family 1, member B10 (zeige ENPP3 Antikörper)) is down-regulated in high-grade versus low-grade endometrial tumors; expression of AKR1B10 correlates with body mass index, with up-regulation of expression of AKR1B10 in obese patients with endometrial tumors.
Result indicate that the differential scanning fluorimetry (DSF) method is useful for enzyme inhibitor drug screening for the AKR superfamily, including AKR1B10 and a structurally similar isoform AKR1B1 (zeige AKR1B1 Antikörper).
Chronic hepatitis C patients expressing high levels of hepatic AKR1B10 had an increased risk of HCC (zeige FAM126A Antikörper) development even after sustained virological response
Various degrees of AKR1B10 upregulation in the liver were observed in patients with chronic HCV infection, and high AKR1B10 expression could be a novel pre- dictor of HCC (zeige FAM126A Antikörper).
AKR1B10 is up-regulated with cisplatin resistance in gastrointestinal cancer cells.
AKR1B10 mRNA and protein levels were higher in primary hepatocellular carcinoma (PHC (zeige SLC25A3 Antikörper)) tissues than in peri (zeige PLIN1 Antikörper)-tumor tissues.
AKR1B16 reduced aliphatic and aromatic carbonyl compounds, using NADPH as a cofactor, with moderate or low activity (highest kcat values around 5 min(-1)). AKR1B16 showed poor inhibition with classical AKR inhibitors, tolrestat being the most potent.
Our results demonstrate that sulindac inhibits pancreatic carcinogenesis by the inhibition of Kras protein prenylation by targeting AKR1B10.
AKR1B15 and Akr1b16 genes are expressed as functional proteins in human and murine tissues [Akr1b16]
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.
aldo-keto reductase family 1 member B10
, aldo-keto reductase family 1, member B10 (aldose reductase)
, SI reductase
, aldo-keto reductase family 1, member B11 (aldose reductase-like)
, aldose reductase-like 1
, aldose reductase-like peptide
, aldose reductase-related protein
, small intestine reductase
, aldo-keto reductase family 1, member B10