AKR1B10 Antikörper (N-Term)

Produktnummer ABIN2775474

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-AKR1B10 Antikörper (ABIN2775474) detektiert spezifisch AKR1B10 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Kaninchen und Saccharomyces cerevisiae.

Kurzübersicht für AKR1B10 Antikörper (N-Term) (ABIN2775474)

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Reaktivität: Human, Maus, Ratte, Pferd, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AKR1B10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AKR1B10 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: AKR1B10 Antibody - N-terminal region

Sequenz: NEHEVGEAIQ EKIQEKAVKR EDLFIVSKLW PTFFERPLVR KAFEKTLKDL

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Yeast: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AKR1B10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B10

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP42553-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AKR1B10 Antikörper (ABIN2775474)

Cheng, Zhang, Kotani, Watanabe, Lee, Wang, Kawashima, Tai, Taniguchi, Honke: "Production of a recombinant single-chain variable-fragment (scFv) antibody against sulfoglycolipid." in: Journal of biochemistry, Vol. 137, Issue 3, pp. 415-21, (2005) (PubMed).

Details zu AKR1B10

Target: AKR1B10 (Aldo-Keto Reductase Family 1, Member B10 (Aldose Reductase) (AKR1B10))

Andere Bezeichnung: AKR1B10

Hintergrund:

Background Information: AKR1B10 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member can efficiently reduce aliphatic and aromatic aldehydes, and it is less active on hexoses. It is highly expressed in adrenal gland, small intestine, and colon, and may play an important role in liver carcinogenesis.

Gene Name: Aldo-keto reductase family 1, member B10 (aldose reductase)

Alternative Symbols: HIS, HSI, ARL1, ARL-1, ALDRLn, AKR1B11, AKR1B12

Protein Name: Aldo-keto reductase family 1 member B10

Molekulargewicht: 35kDa

Gen-ID: 57016

NCBI Accession: NP_064695

UniProt: O60218