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The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 22.214.171.124), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006 [PubMed 16616524]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.
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ADHFe1 is an enzyme involved in retinoic acid-dependent Hox activation
These results demonstrate that the promoter hypermethylation of ADHFE1 is frequently present in CRC and alcohol induces methylation-mediated down expression of ADHFE1 and proliferation of CRC cells.
ADHFE1 has an important role of differentiation in CRC, as well as normal colorectal mucosa and embryonic developmental processes.
cloned and characterized an iron-activated alcohol dehydrogenase gene, Fe-containing alcohol dehydrogenase 1 (ADHFe1)
show that the ADHFe1 gene is related to bacterial GHB dehydrogenases and has a conserved NAD-binding site
Adhfe1 is a novel alcohol dehydrogenase with mitochondrial localization
The ADHFE1 gene encodes hydroxyacid-oxoacid transhydrogenase (EC 126.96.36.199), which is responsible for the oxidation of 4-hydroxybutyrate in mammalian tissues (Kardon et al., 2006
, alcohol dehydrogenase iron-containing protein 1
, hydroxyacid-oxoacid transhydrogenase, mitochondrial
, alcohol dehydrogenase, iron containing, 1
, Fe-containing alcohol dehydrogenase 1
, alcohol dehydrogenase 8