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AP1m2 encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family.
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AP-1B is required for protein sorting and polarization of intestinal cells in mice. Loss of AP-1B in the intestinal epithelia results in mislocalization of E-cadherin (zeige CDH1 Antikörper), activation of beta-catenin (zeige CTNNB1 Antikörper)/Tcf4 (zeige TCF4 Antikörper) complex, proliferation, and hyperplasia.
Variants in AP1M2 gene is associated with thrombosis.
Results suggest that mu1B interacts with different classes of basolateral targeting signals in distinct ways.
The AP1M2 gene was shown to effectively separate these two tumor(chromophobe renal cell carcinoma (zeige MOK Antikörper) (RCC (zeige XRCC1 Antikörper)) and benign oncocytoma) groups by quantitative reverse transcription-PCR using fresh tissue samples, with similar trends seen on formalin-fixed tissues.
PIPKIgamma also interacts with the mu subunits of clathrin adaptor protein (AP) complexes
The mechanism of iron absorption from mineralized Soybean ferritin (zeige FTL Antikörper) using Caco-2 cells via a mu2 (zeige AP2M1 Antikörper)-dependent endocytosis mechanism is reported.
This gene encodes a subunit of the heterotetrameric adaptor-related protein comlex 1 (AP-1), which belongs to the adaptor complexes medium subunits family. This protein is capable of interacting with tyrosine-based sorting signals.
AP-1 complex subunit mu-2
, adaptor-related protein complex 1, mu 2 subunit
, AP-1 complex subunit mu-2-like
, AP-mu chain family member mu1B
, adaptor protein complex AP-1 mu-2 subunit
, adaptor-related protein complex 1 mu-2 subunit
, adaptor-related protein complex AP-1, mu 2 subunit
, clathrin assembly protein complex 1 medium chain 2
, golgi adaptor HA1/AP1 adaptin mu-2 subunit
, mu-adaptin 2
, HA1 47 kDa subunit 2
, clathrin coat assembly protein AP47 2
, clathrin coat associated protein AP47 2
, clathrin-associated adaptor medium chain mu2
, golgi adaptor AP-1 47 kDa protein