anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antikörper

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (21) und ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 279 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-ABCB1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>NCI-H226 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Anmelden zum Anzeigen 1 bis 2 Tage
$139.00
Details
Human Kaninchen Unkonjugiert IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Hund Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$636.30
Details
Human Maus Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$430.10
Details
Human Maus Unkonjugiert IHC (fro), IF, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Human Maus Unkonjugiert IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p) Anti-ABCB1 / MDR1 antibody  ABIN1048283 IHC staining of human kidney, proximal convoluted tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Hamster Kaninchen Unkonjugiert IHC (p), WB Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Maus Unkonjugiert FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$346.50
Details

ABCB1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antikörper

  1. Human Polyclonal ABCB1 Primary Antibody für IHC, IHC (p) - ABIN4333368 : Bernstein, Hölzl, Dobrowolny, Hildebrandt, Trübner, Krohn, Bogerts, Pahnke: Vascular and extravascular distribution of the ATP-binding cassette transporters ABCB1 and ABCC1 in aged human brain and pituitary. in Mechanisms of ageing and development 2015 (PubMed)
    Show all 2 Pubmed References

  2. Human Monoclonal ABCB1 Primary Antibody für ELISA, WB - ABIN1724923 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal ABCB1 Primary Antibody für ELISA, WB - ABIN1724927 : Rubi?, Ho?ysz, Barczak, Gryczka, ?aci?ski, Jagielski, Czernikiewicz, Pó?rolniczak, Wojewoda, Perz, Bia?ek, Morze, Kandu?a, Lisiak, Mrozikiewicz, Grodecka-Gazdecka, Rybczy?ska: Study of ABCB1 polymorphism frequency in breast cancer patients from Poland. in Pharmacological reports : PR 2013 (PubMed)
    Show all 2 Pubmed References

  4. Human Monoclonal ABCB1 Primary Antibody für IHC (fro), FACS - ABIN2479419 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479421 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 4 Pubmed References

  6. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479422 : Koziolek, Riess, Geiger, Thévenod, Hauser: Expression of multidrug resistance P-glycoprotein in kidney allografts from cyclosporine A-treated patients. in Kidney international 2001 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal ABCB1 Primary Antibody für FACS - ABIN2479424 : Park, Lomri, Simeoni, Fruehauf, Mechetner: Analysis of P-glycoprotein-mediated membrane transport in human peripheral blood lymphocytes using the UIC2 shift assay. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2003 (PubMed)
    Show all 4 Pubmed References

  8. Human Monoclonal ABCB1 Primary Antibody für ICC, IHC (fro) - ABIN3043101 : Gao, Liu, Wang, Lin, Zhang: Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. in Medical oncology (Northwood, London, England) 2010 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal ABCB1 Primary Antibody für IHC (fro), IHC (p) - ABIN3043967 : Wang, Deng, Lu, Xu, Yan, Ye, Chen et al.: Gambogic acid as a non-competitive inhibitor of ATP-binding cassette transporter B1 reverses the multidrug resistance of human epithelial cancers by promoting ATP-binding cassette transporter B1 ... in Basic & clinical pharmacology & toxicology 2012 (PubMed)
    Show all 2 Pubmed References

  10. Hamster Monoclonal ABCB1 Primary Antibody für FACS, ICC - ABIN4333365 : Kurihara, Sato, Akimoto, Ogura, Ito: Identification and characterization of ABCB1-mediated and non-apoptotic sebum secretion in differentiated hamster sebocytes. in Biochimica et biophysica acta 2011 (PubMed)

Weitere Antikörper gegen ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaktionspartner

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. P-gp (zeige ABCB4 Antikörper), Bcrp (zeige ABCG2 Antikörper) and Mrp1 (zeige ABCC1 Antikörper) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. Results show that CD133 and MDR1 (zeige TBC1D9 Antikörper) expression increase in recurrent pediatric pilocytic astrocytomas (PAs (zeige PASK Antikörper)) following chemotherapy, and in drug resistant tumor cells. CD133 regulates MDR1 (zeige TBC1D9 Antikörper) expression via the PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper)/NF-kappaB (zeige NFKB1 Antikörper) signaling. These results provide evidence that CD133 contributes to multidrug resistance by regulating MDR1 (zeige TBC1D9 Antikörper) levels via the PI3K (zeige PIK3CA Antikörper)-Akt (zeige AKT1 Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) signal pathway.

  2. PG accumulation assay is a new, unique tool for the parallel determination of the function of the ABCG2 (zeige ABCG2 Antikörper), ABCB1, and ABCC1 (zeige ABCC1 Antikörper) multidrug transporters

  3. Abcb1a/b(-/-);Abcg2 (zeige ABCG2 Antikörper)(-/-) mice revealed increased brain penetration of rapamycin (13-fold), AZD8055 (7.7-fold), and NVP-BEZ235 (4.5-fold), but not ZSTK474 relative to WT mice. Importantly, ABC (zeige ABCB6 Antikörper) transporters limited rapamycin brain penetration to subtherapeutic levels, while the reduction in NVP-BEZ235 brain penetration did not prevent target inhibition.

  4. ABCB1 genotype is not a significant determinant of interindividual variability in dabigatran and rivaroxaban pharmacokinetics

  5. High MDR1 (zeige TBC1D9 Antikörper) expression is associated with multidrug resistance in breast cancer.

  6. inhibition of autophagy led to the decrease in stemness, restoration of mitochondrial proteins and reduced expression of CD44 (zeige CD44 Antikörper), ABCB1 and ADAM17 (zeige ADAM17 Antikörper)

  7. The T-allele of ABCB1-C3435T gene polymorphism has demonstrated to be a good prognosis factor for resistance, progression free survival and overall survival in HER2 (zeige ERBB2 Antikörper)-positive Breast Cancer patients.

  8. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (zeige ABCB4 Antikörper)--{REVIEW}

  9. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  10. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (zeige ABCC6 Antikörper), ABCB1 and CYP2C8 (zeige CYP2C8 Antikörper) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Interaktionspartner

  1. Molecular Dynamics simulations and docking of drugs performed for P-gp (P-gp (zeige ABCB4 Antikörper), multi-drug resistance protein, MDR1 (zeige ABCB4 Antikörper)).Drugs with ER < 1 (zeige MIER1 Antikörper) almost do not bind the main binding cavity (MBC (zeige CACNA1C Antikörper)) of P-gp (zeige ABCB4 Antikörper).

  2. conclusion, MDR1 (zeige ABCB4 Antikörper) and BCRP (zeige ABCG2 Antikörper) are expressed on apical membranes of the rodent placental SynT (zeige STX1A Antikörper)-II layer.

  3. Mdr1 (zeige ABCB4 Antikörper) enforces T Cell homeostasis in the presence of intestinal bile acids.

  4. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  5. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (zeige ABCB4 Antikörper) ATPase (zeige DNAH8 Antikörper) activity

  6. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  7. Chrysosplenetin inhibited P-gp (zeige ABCB4 Antikörper) activity and reverse the up-regulated P-gp (zeige ABCB4 Antikörper) and MDR1 (zeige ABCB4 Antikörper) levels induced by artemisinin.

  8. Tamsulosin and tolterodine with P-gp (zeige ABCB4 Antikörper) gene expression and activity in an enantiomer-specific way.

  9. Pgp (zeige ABCB4 Antikörper)-coupled ATPase (zeige DNAH8 Antikörper) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  10. Data show that human transgenic mutant huntingtin (zeige HTT Antikörper) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (zeige ABCB4 Antikörper)) which suggests that MDR1 (zeige ABCB4 Antikörper) might be a potential therapeutic target for Huntington's disease.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen-Profil

Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) Antikörper
  • ATP binding cassette subfamily B member 1A (Abcb1a) Antikörper
  • ATP binding cassette subfamily B member 1 (Abcb1) Antikörper
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) Antikörper
  • malic enzyme complex, mitochondrial (Mod2) Antikörper
  • ABC20 Antikörper
  • ABCB1 Antikörper
  • Cd243 Antikörper
  • CLCS Antikörper
  • GP170 Antikörper
  • Mdr Antikörper
  • Mdr-1 Antikörper
  • Mdr1 Antikörper
  • Mdr1a Antikörper
  • Mdr1b Antikörper
  • Mod-2 Antikörper
  • Mod-2r Antikörper
  • Mod-2s Antikörper
  • Mod2-r Antikörper
  • Mod2-s Antikörper
  • p-gp Antikörper
  • PGP1 Antikörper
  • Pgy-1 Antikörper
  • Pgy1 Antikörper
  • xemdr Antikörper

Bezeichner auf Proteinebene für ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPEZIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
Ausgewählte Anbieter für anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antikörper
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