Protein Überblick

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Genbezeichner und Symbole assoziert mit ABCB1

• ATP binding cassette subfamily B member 1 (ABCB1) Antikörper
• ATP binding cassette subfamily B member 1A (Abcb1a) Antikörper
• ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) Antikörper
• ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) Antikörper
• ATP binding cassette subfamily B member 1 (Abcb1) Antikörper

• ABC20 Antikörper
• ABCB1 Antikörper
• CD243 Antikörper
• CLCS Antikörper
• GP170 Antikörper
• Alle Synonyme
• mdr Antikörper
• Mdr1 Antikörper
• Mdr1a Antikörper
• Mdr1b Antikörper
• p-gp Antikörper
• PGP1 Antikörper
• Pgy-1 Antikörper
• Pgy1 Antikörper
• xemdr Antikörper

Bezeichner auf Proteinebene für ABCB1

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , bovine P-glycoprotein , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B