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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antikörper

Bezeichnung:
anti-SMAD, Mothers Against DPP Homolog 1 Antikörper (SMAD1)
Auf www.antikoerper-online.de finden Sie aktuell 330 SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SMAD, Mothers Against DPP Homolog 1 Kits (49) und SMAD, Mothers Against DPP Homolog 1 Proteine (22) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 420 SMAD, Mothers Against DPP Homolog 1 Produkte verfügbar.
Synonyme:
2/23, AI528653, apg, BSP-1, BSP1, c28, CG12399, dMad, Dmel\\CG12399, E(zen)2, En(vvl), fb39h09, JV4-1, JV41, l(2)k00237, mad, Madh1, Madr1, Mat, MLP, Mlp1, MusMLP, p-Mad, pMad, pSmad, Smad, smad-1, smad1, wu:fb39h09, wu:fb97e04, xmad, Xmad1, Xsmad1
Alle Antikörper anzeigen Gen GeneID UniProt
SMAD1 4086 Q15797
SMAD1 17125 P70340
SMAD1 25671  

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Am meisten referenzierte anti-SMAD, Mothers Against DPP Homolog 1 Antikörper

  1. Human Monoclonal SMAD1 Primary Antibody für IF, WB - ABIN393492 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Zeige alle 5 Referenzen für ABIN393492

  2. Human Polyclonal SMAD1 Primary Antibody für WB - ABIN1881815 : Ye, Yu, Hu, Lu, Xie: Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma. in Journal of experimental & clinical cancer research : CR 2010 (PubMed)
    Zeige alle 4 Referenzen für ABIN1881815

  3. Human Polyclonal SMAD1 Primary Antibody für ELISA, WB - ABIN1533926 : Liu, Hata, Baker, Doody, Cárcamo, Harland, Massagué: A human Mad protein acting as a BMP-regulated transcriptional activator. in Nature 1996 (PubMed)
    Zeige alle 2 Referenzen für ABIN1533926

  4. Human Polyclonal SMAD1 Primary Antibody für IF, ELISA - ABIN1532647 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. in Cell 1996 (PubMed)
    Zeige alle 2 Referenzen für ABIN1532647

  5. Chicken Polyclonal SMAD1 Primary Antibody für WB - ABIN2779411 : Blount, Merlie: BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor. in The Journal of cell biology 1991 (PubMed)
    Zeige alle 2 Referenzen für ABIN2779411

  6. Cow (Bovine) Polyclonal SMAD1 Primary Antibody für IHC, WB - ABIN2780719 : Jadlowiec, Zhang, Li, Campbell, Sfeir: Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. in The Journal of biological chemistry 2006 (PubMed)

  7. Bonobo Polyclonal SMAD1 Primary Antibody für EIA, WB - ABIN401471 : Sapkota, Alarcón, Spagnoli, Brivanlou, Massagué: Balancing BMP signaling through integrated inputs into the Smad1 linker. in Molecular cell 2007 (PubMed)

Weitere Antikörper gegen SMAD, Mothers Against DPP Homolog 1 Interaktionspartner

Zebrafish SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. Data show that interplay of Smad1/5 and MAP kinase (zeige MAPK1 Antikörper) signaling system (ERK (zeige MAPK1 Antikörper) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  2. this study uncovers that smad1 and smad9 (zeige SMAD9 Antikörper) act redundantly to each other downstream of smad5 (zeige SMAD5 Antikörper) to mediate ventral specification and to regulate embryonic myelopoiesis.

  3. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 and Smad5 (zeige SMAD5 Antikörper).

Fruit Fly (Drosophila melanogaster) SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling.

  2. Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues.

  3. During development, synaptic pMad accumulation followed the arrival and clustering of ionotropic glutamate (zeige GRIN2A Antikörper) receptors at neuromuscular junction synapses.

  4. The actions of Brat at synapses are mediated through mothers against decapentaplegic (Mad), the signal transduction effector of the bone morphogenetic protein (BMP) signaling pathway.

  5. Mad has distinct signal transduction roles in the BMP (zeige TGFb Antikörper) and Wnt (zeige WNT4 Antikörper) pathways depending on its phosphorylation state.

  6. Yorkie (zeige YAP1 Antikörper) and Mad physically bind each other, and 410 bp minimal enhancer of bantam that responds to Yorkie:Mad in vivo and in cultured cells, was identified.

  7. Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.

  8. importin (zeige KPNA4 Antikörper)-beta11 function interacts with the bone morphogenic protein (zeige TGFb Antikörper) pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function

  9. Mad depletion or overexpression produced Wingless-like embryonic segmentation phenotypes

  10. The downstream transcription factor Mothers against dpp is essential for the normal structural and functional development of the Drosophila neuromuscular junction, a synapse that displays activity-dependent plasticity.

Human SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. A significant association was found between the low expression of inhibitory protein SMAD-7 (zeige SMAD7 Antikörper) and both zeta-chain-associated protein kinase (zeige CDK7 Antikörper) 70-negative cells (p = 0.04) and lower apoptotic index (p = 0.004). No differences were observed in SMAD-2 (zeige SMAD2 Antikörper)/3 expression. In conclusion, our results demonstrate a significant correlation between greater SMAD-1 (zeige GARS Antikörper)/8 and lower SMAD-4 (zeige SMAD4 Antikörper) expression in chronic lymphocytic leukemia cells

  2. melatonin treatment was found to downregulate TNFalpha (zeige TNF Antikörper)-induced SMURF1 (zeige SMURF1 Antikörper) expression and then decrease SMURF1 (zeige SMURF1 Antikörper)-mediated ubiquitination and degradation of SMAD1 (zeige GARS Antikörper) protein

  3. The expression of specific targets Smad1 (zeige GARS Antikörper) and Osterix (zeige SP7 Antikörper) was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (zeige MUC7 Antikörper)+). As miR (zeige MLXIP Antikörper)-30b, miR (zeige MLXIP Antikörper)-133a, and miR (zeige MLXIP Antikörper)-143 are negatively regulated by Pi and restored by Mg(2 (zeige MUC7 Antikörper)+) with a congruent modulation of their known targets Runx2 (zeige RUNX2 Antikörper), Smad1 (zeige GARS Antikörper), and Osterix (zeige SP7 Antikörper), our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

  4. the BMP-2 (zeige BMP2 Antikörper)/Smad1 (zeige GARS Antikörper)/5/RUNX2 (zeige RUNX2 Antikörper) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (zeige BGLAP Antikörper) synth

  5. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1 (zeige GARS Antikörper).

  6. The expression SMAD1 (zeige GARS Antikörper) protein showed a significant correlation with lung cancer differentiation and lymphatic metastasis (P < 0.05), but not with genders, ages, tumor sizes and histological types of lung cancer patients (P>0.05).

  7. Overexpression of Smad1 (zeige GARS Antikörper) is associated with prostate cancer.

  8. SMAD1 (zeige GARS Antikörper) signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development.

  9. Smad1 (zeige GARS Antikörper) elevation serves as a compensatory mechanism for p53 (zeige TP53 Antikörper) deficiency by potentiating the activation of p53 (zeige TP53 Antikörper) parallel pathways.

  10. Our data indicated that downregulation of miR (zeige MLXIP Antikörper)-26b in osteosarcoma elevated the levels of CTGF (zeige CTGF Antikörper) and Smad1 (zeige GARS Antikörper), facilitating osteosarcoma metastasis

Mouse (Murine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. BetA can enhance in vivo osteogenic potentials of BMP2 (zeige BMP2 Antikörper), possibly via stimulating Smad 1/5/8 and p38 (zeige CRK Antikörper) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

  2. Mutant GDF5 (zeige GDF5 Antikörper) enhances ameloblast differentiation via accelerated BMP2 (zeige BMP2 Antikörper)-induced Smad1-Smad5 (zeige SMAD5 Antikörper)-Smad8 (zeige SMAD9 Antikörper) phosphorylation.

  3. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1.

  4. Data show that in R-Smad proteins Smad1;Smad5 (zeige SMAD5 Antikörper) knockout embryonic stem cells (mESCs), the bone morphogenetic proteins (BMP)-SMAD signaling is dispensable for self-renewal.

  5. Data show that R-Smad Proteins SMAD1 and SMAD5, which transduce bone morphogenetic protein (BMP) signals, recognize enhancer regions together with Kruppel-like factors KLF4 and KLF5 in naive embryonic stem cell (mESCs).

  6. AHNAK (zeige AHNAK Antikörper) plays a crucial role in body fat accumulation by regulating adipose tissue development via interaction with the SMAD1 protein and can be involved in metabolic homeostasis

  7. Results show that Smad1-deficient mice exhibit enhanced neuronal survival and improved neurological recovery at 7 days after transient middle cerebral artery occlusion suggesting that Smad1-mediated signal pathway is involved in stroke pathophysiology.

  8. The study reveals a novel miR (zeige MLXIP Antikörper)-26a-GSK3beta (zeige GSK3b Antikörper)-Smad1 signaling pathway in the regulation of mammalian axon regeneration.

  9. Nondiabetic Smad1-Tg had normal kidney however, diabetes resulted in mesangial expansion, consistent with an increase in glomerular phosphorylated Smad1. Heterozygous Smad1 KO mice exhibit attenuated mesangial expansion in the diabetic condition.

  10. The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (zeige BMP2 Antikörper)/Smad1/5/8 and Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathways.

Xenopus laevis SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. interactions between miR (zeige MYLIP Antikörper)-26 and the Smad1 3'UTR (zeige UTS2R Antikörper) modulate Smad1 function in the establishment of axial patterning.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) Interaktionspartner

  1. a detailed computational model for TGF-beta (zeige TGFB1 Antikörper) signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2 (zeige SMAD2 Antikörper)/3 channels through a negative feedback loop dependent on Smad7 (zeige SMAD7 Antikörper).

SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with SMAD, Mothers Against DPP Homolog 1 (SMAD1)

  • SMAD family member 1 (smad1) Antikörper
  • SMAD family member 1 (SMAD1) Antikörper
  • MAD homolog 1 (Drosophila) (smad1) Antikörper
  • Mothers against dpp (Mad) Antikörper
  • SMAD family member 1 (Smad1) Antikörper
  • SMAD family member 1 (smad1-a) Antikörper
  • 2/23 Antikörper
  • AI528653 Antikörper
  • apg Antikörper
  • BSP-1 Antikörper
  • BSP1 Antikörper
  • c28 Antikörper
  • CG12399 Antikörper
  • dMad Antikörper
  • Dmel\\CG12399 Antikörper
  • E(zen)2 Antikörper
  • En(vvl) Antikörper
  • fb39h09 Antikörper
  • JV4-1 Antikörper
  • JV41 Antikörper
  • l(2)k00237 Antikörper
  • mad Antikörper
  • Madh1 Antikörper
  • Madr1 Antikörper
  • Mat Antikörper
  • MLP Antikörper
  • Mlp1 Antikörper
  • MusMLP Antikörper
  • p-Mad Antikörper
  • pMad Antikörper
  • pSmad Antikörper
  • Smad Antikörper
  • smad-1 Antikörper
  • smad1 Antikörper
  • wu:fb39h09 Antikörper
  • wu:fb97e04 Antikörper
  • xmad Antikörper
  • Xmad1 Antikörper
  • Xsmad1 Antikörper

Bezeichner auf Proteinebene für SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1

GENE ID SPEZIES
493211 Xenopus (Silurana) tropicalis
574340 Macaca mulatta
30628 Danio rerio
33529 Drosophila melanogaster
4086 Homo sapiens
17125 Mus musculus
25671 Rattus norvegicus
379664 Xenopus laevis
395680 Gallus gallus
475456 Canis lupus familiaris
397016 Sus scrofa
540488 Bos taurus
450142 Pan troglodytes
100432108 Pongo abelii
100033850 Equus caballus
443229 Ovis aries
100341544 Oryctolagus cuniculus
100727257 Cavia porcellus
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