anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Antikörper

Bezeichnung:
anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Antikörper (CTNNA1)
Auf www.antikoerper-online.de finden Sie aktuell 171 Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Kits (28) und Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 209 Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Produkte verfügbar.
Synonyme:
2010010M04Rik, a-cat, AA517462, AI988031, Alpha-Cat, alpha-catenin, alpha-ctn, alphacat, CAP102, Catna1, CG17947, CT39986, ctnna, CTNNA1, Dalpha-cat, DalphaC, Dalphacat, DgriGH19548, dgri_GLEANR_3829, Dmcatp, Dmel\\CG17947, GH19548
Alle Antikörper anzeigen Gen GeneID UniProt
CTNNA1 12385 P26231
CTNNA1 1495 P35221
CTNNA1 307505  

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Am meisten referenzierte anti-Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Antikörper

  1. Chicken Monoclonal CTNNA1 Primary Antibody für IF, IP - ABIN967813 : Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. in Proceedings of the National Academy of Sciences of the United States of America 2001 (PubMed)
    Zeige alle 5 Referenzen für 967813

  2. Chicken Monoclonal CTNNA1 Primary Antibody für IF, IP - ABIN967812 : Hirano, Kimoto, Shimoyama, Hirohashi, Takeichi: Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. in Cell 1992 (PubMed)
    Zeige alle 5 Referenzen für 967812

  3. Human Polyclonal CTNNA1 Primary Antibody für WB - ABIN401554 : Lipinski, Yuan: A cellular response to an internal energy crisis. in Cell 2005 (PubMed)
    Zeige alle 4 Referenzen für 401554

  4. Human Polyclonal CTNNA1 Primary Antibody für WB - ABIN319361 : Daneman, Barres: The blood-brain barrier--lessons from moody flies. in Cell 2005 (PubMed)
    Zeige alle 4 Referenzen für 319361

  5. Human Polyclonal CTNNA1 Primary Antibody für EIA, IHC (p) - ABIN1449661 : Shimoyama, Nagafuchi, Fujita, Gotoh, Takeichi, Tsukita, Hirohashi: Cadherin dysfunction in a human cancer cell line: possible involvement of loss of alpha-catenin expression in reduced cell-cell adhesiveness. in Cancer research 1992 (PubMed)
    Zeige alle 2 Referenzen für 1449661

  6. Human Monoclonal CTNNA1 Primary Antibody für FACS, ICC - ABIN261465 : Bajpai, Feng, Krishnamurthy, Longmore, Wirtz: Loss of alpha-catenin decreases the strength of single E-cadherin bonds between human cancer cells. in The Journal of biological chemistry 2009 (PubMed)

  7. Human Polyclonal CTNNA1 Primary Antibody für IHC (p), IHC - ABIN251400 : Lynch, Grady, Suriano, Huntsman: Gastric cancer: new genetic developments. in Journal of surgical oncology 2005 (PubMed)

Weitere Antikörper gegen Catenin (Cadherin-Associated Protein), alpha 1, 102kDa Interaktionspartner

Fruit Fly (Drosophila melanogaster) Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Interaktionspartner

  1. alpha-Catenin controls actomyosin dynamics by stabilising and promoting the formation of actomyosin foci, and also stabilises DE-Cadherin (Drosophila E-Cadherin (zeige CDH1 Antikörper), also known as Shotgun) at the cell membrane, suggesting that medioapical actomyosin contractility regulates junction stability.

  2. Increased Rap1 (zeige TERF2IP Antikörper) activity restricts epithelial invagination in an alpha-catenin-dependent manner.

  3. alpha-Cat mutant phenotype can be rescued by the expression of a DE-cadherin::alpha-Catenin fusion protein, which argues against an essential cytosolic, cadherin-independent role of Drosophila alpha-Catenin

  4. alpha-catenin and p120(ctn (zeige CTNND1 Antikörper)) are key players in a mechanism of recruiting Rho1 to its sites of action.

Zebrafish Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Interaktionspartner

  1. Depletion of alphaE-catenin caused a defect in radial intercalation that was associated with decreased cell-cell adhesion, in a similar manner to E-cadherin (zeige CDH1 Antikörper) depletion. Depletion of alphaE-catenin also caused deep cells to have plasma membrane blebbing.

Mouse (Murine) Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Interaktionspartner

  1. cadherin 2 (CDH2 (zeige CDH2 Antikörper)) and CDH4 (zeige CDH4 Antikörper) cooperate to regulate radial migration in mouse brain via the protein tyrosine phosphatase 1B (PTP1B (zeige PTPN1 Antikörper)) and alpha- and beta-catenins.

  2. alphaT-catenin is a constitutively active actin-binding protein that can physically couple the cadherin.catenin complex to F-actin in the absence of tension.

  3. Two Dtna (zeige DTNA Antikörper) interactors, alpha-catulin (zeige CTNNAL1 Antikörper) (phosphorylation independent) and Grb2 (zeige GRB2 Antikörper) (phosphorylation dependent) are localized to neuromuscular junctions in vivo, and are required for proper organization of neurotransmitter receptors on myotubes.

  4. alphaE-catenin inhibits beta4 integrin-mediated activation of SRC (zeige SRC Antikörper) tyrosine kinase (zeige TYRO3 Antikörper)

  5. E-cadherin (zeige CDH1 Antikörper)/alphaE-catenin chimeras used previously do not mimic alphaE-catenin in the native CCC, and imply that both CCC-bound monomer and cytosolic homodimer alphaE-catenin are required for strong cell-cell adhesion.

  6. Loss of alpha-catenin elicits a cholestatic response and impairs liver regeneration

  7. alphaE-catenin binding to filamentous actin favors assembly of unbranched filament bundles that are protected from severing over more dynamic, branched filament arrays.

  8. Fusing VE-cadherin (zeige CDH5 Antikörper) to alpha-catenin presents a mutation, which leads to embryonic lethality, due to a lack of fetal liver hematopoiesis and severe lymphedema but no detectable defects in blood vessel formation and remodeling.

  9. alphaE-catenin recruits vinculin to adherens junctions more effectively than alphaN-catenin, partly because of its higher affinity for actin filaments.

  10. our results show that alpha-catenin-mediated cell adhesion and cell organization are important for the fissure closure in mice, and further suggest that genes that regulate cell adhesion may underlie certain coloboma cases in humans

Human Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Interaktionspartner

  1. The results of this study demonstrate that causative variants identified in the CTNNA1 and CYP4V2 (zeige CYP4V2 Antikörper) genes are also associated with Leber Congenital Amaurosis.

  2. alpha- and beta-catenins may be important in the early stages of phyllodes tumours development, while E-cadherin (zeige CDH1 Antikörper) may be required for malignant development

  3. This work identified alpha-catenin as another molecule in addition to E- and P-cadherin that were targeted to inactivate homotypic cell-in-cell structures formation in human tumor cells.

  4. Progressive loss of e-cadherin (zeige CDH1 Antikörper)/alpha-catenin expression is associated with an aggressive phenotype (low differentiation, increased metastatic activity/advanced stage) in thyroid carcinomas.

  5. study identifies CTNNA1 gene variants as a cause of macular dystrophy, indicates that CTNNA1 is involved in maintaining RPE (zeige RPE Antikörper) integrity

  6. The results demonstrate a Fas (zeige FAS Antikörper)-mediated apoptotic signaling pathway that is enhanced by the age-dependent loss of alpha(E)-catenin in renal tubule epithelial cells.

  7. Actin-dependent CTNNA1 clustering is a unique molecular mechanism mediating both integrity and reassembly of the cell-cell adhesive interface formed through weak cis (zeige CISH Antikörper)- and trans-intercadherin interactions.

  8. alpha-catenin is a reversible, stretch-activatable sensor that mechanically links cadherin complexes and actin and is an indispensable player in cadherin-specific mechanotransduction at intercellular junctions.

  9. alpha-catenin functions as a tumor suppressor in E-cadherin (zeige CDH1 Antikörper)-negative basal like breast cancer cells by inhibiting NF-kappaB (zeige NFKB1 Antikörper) signaling.

  10. CTNNA1 hypermethylation was detected in three out of four with isolated del(5q), one with trisomy 11, one with monosomy 7, one out of four with del(20q), and one out of seven with complex abnormalities, but in none with trisomy 8.

Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1) Antigen-Profil

Beschreibung des Gens

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

Alternative names and synonyms associated with Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1)

  • catenin (cadherin-associated protein), alpha 1, 102kDa (CTNNA1) Antikörper
  • alpha Catenin (alpha-Cat) Antikörper
  • alpha Catenin (Dgrialpha-Cat) Antikörper
  • catenin alpha-1 (Tsp_10127) Antikörper
  • catenin (cadherin-associated protein), alpha 1, 102kDa (ctnna1) Antikörper
  • catenin (cadherin associated protein), alpha 1 (Ctnna1) Antikörper
  • catenin (cadherin-associated protein), alpha 1 (ctnna1) Antikörper
  • catenin (cadherin-associated protein), alpha 1, 102kDa (Ctnna1) Antikörper
  • catenin (cadherin-associated protein), alpha 2 (CTNNA2) Antikörper
  • 2010010M04Rik Antikörper
  • a-cat Antikörper
  • AA517462 Antikörper
  • AI988031 Antikörper
  • Alpha-Cat Antikörper
  • alpha-catenin Antikörper
  • alpha-ctn Antikörper
  • alphacat Antikörper
  • CAP102 Antikörper
  • Catna1 Antikörper
  • CG17947 Antikörper
  • CT39986 Antikörper
  • ctnna Antikörper
  • CTNNA1 Antikörper
  • Dalpha-cat Antikörper
  • DalphaC Antikörper
  • Dalphacat Antikörper
  • DgriGH19548 Antikörper
  • dgri_GLEANR_3829 Antikörper
  • Dmcatp Antikörper
  • Dmel\\CG17947 Antikörper
  • GH19548 Antikörper

Bezeichner auf Proteinebene für CTNNA1

CG17947-PA , D-alpha-catenin , Dalpha-Catenin , Dalpha-cadherin , DalphaCatenin , a-catenin , alpha catenin , alpha-Cat-PA , alpha-Catenin , alphaCatenin , catenin alpha 1 subunit , catenin alpha-1 , DgriGH19548-PA , Dgrialpha-Cat-PA , GH19548-PA , catenin (cadherin-associated protein), alpha 1, 102kDa , catenin alpha-1-like , 102 kDa cadherin-associated protein , CAP102 , alpha E catenin , alpha E-catenin , alpha(E)-catenin , cadherin associated protein , catenin alpha 1 , [a]E-catenin , alpha-E-catenin , alpha-catenin , alphaE-catenin , cadherin-associated protein,102kDa , renal carcinoma antigen NY-REN-13 , catenin (cadherin associated protein), alpha 1 , catenin, alpha 1

GENE ID SPEZIES
100072548 Equus caballus
40517 Drosophila melanogaster
450165 Pan troglodytes
574385 Macaca mulatta
6563215 Drosophila grimshawi
10905794 Trichinella spiralis
100020276 Monodelphis domestica
100091564 Ornithorhynchus anatinus
100407624 Callithrix jacchus
100453792 Pongo abelii
100483944 Ailuropoda melanoleuca
100538100 Danio rerio
100550456 Meleagris gallopavo
12385 Mus musculus
30741 Danio rerio
1495 Homo sapiens
474698 Canis lupus familiaris
307505 Rattus norvegicus
416184 Gallus gallus
100523778 Sus scrofa
526848 Bos taurus
100328952 Oryctolagus cuniculus
483088 Canis lupus familiaris
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