RAS P21 Protein Activator (GTPase Activating Protein) 1 ELISA Kits (RASA1)
Auf www.antikoerper-online.de finden Sie aktuell 4 RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) ELISA Kits von 2 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RASA1 Antikörper (103) und RASA1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 118 RASA1 Produkte verfügbar.
CG9209, CM-AVM, CMAVM, D-RasGAP, Dmel\\CG9209, Gap, GAPX, p120GAP, p120RASGAP, PKWS, RAS-GAP, Rasa, RASGAP

Weitere ELISA Kits für RASA1 Interaktionspartner

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. QKI-5 (zeige QKI ELISA Kits) stabilized RASA1 mRNA via directly binding to the QKI (zeige QKI ELISA Kits) response element region of RASA1, which in turn prevented the activation of the Ras-MAPK (zeige MAPK1 ELISA Kits) signaling pathway, suppressed cellular proliferation and induced cell cycle arrest.

  2. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  3. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  4. PTP1B (zeige PTPN1 ELISA Kits) dephosphorylates PITX1 (zeige PITX1 ELISA Kits) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  5. Data suggest that, in response to netrin-1 (zeige NTN1 ELISA Kits)/netrin receptor (DCC (zeige DCC ELISA Kits)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (zeige SRC ELISA Kits) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  6. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  7. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (zeige GNAQ ELISA Kits) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

  8. Data showed that hypoxia regulated the expression of miR (zeige MLXIP ELISA Kits)-182 and RASA1 to promote HCC (zeige FAM126A ELISA Kits) angiogenesis.

  9. p120RasGAP shields Akt (zeige AKT1 ELISA Kits) from deactivating phosphatases in FGF1 (zeige FGF1 ELISA Kits) signaling, but loses this ability once cleaved by caspase-3 (zeige CASP3 ELISA Kits).

  10. Capillary malformation-arteriovenous malformation syndrome (CM-AVM) is an autosomal dominant disorder caused by RASA1 mutations.

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. The data suggest that nitrosylation of H-Ras (zeige HRAS ELISA Kits) rearranges the adsorptive potential and intrinsic GTPase (zeige RACGAP1 ELISA Kits) activity of H-Ras (zeige HRAS ELISA Kits) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) Interaktionspartner

  1. Double-deficient RASA1-neurofibromin 1 (zeige NF1 ELISA Kits) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (zeige NOTCH1 ELISA Kits) gene.

  2. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  3. Regulation of Rasa1 translation by miR (zeige MLXIP ELISA Kits)-132 was seen in severed axons, demonstrating local function within the axon.

  4. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  5. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 GTPase activating protein 1 (RASA1)

  6. 14-3-3 (zeige YWHAQ ELISA Kits) negatively regulates the RGC downstream of the PI3-kinase (zeige PIK3CA ELISA Kits)/Akt (zeige AKT1 ELISA Kits) signaling pathway

  7. Caspase-3 (zeige CASP3 ELISA Kits) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (zeige AKT1 ELISA Kits).

  8. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

  9. Ca2 (zeige CA2 ELISA Kits)+-dependent monomer and dimer formation switches CAPRI (zeige RASA4 ELISA Kits) Protein between Ras GTPase-activating protein (GAP) and RapGAP (zeige RAP1GAP ELISA Kits) activities

  10. statins inhibit GGPP biosynthesis in the mevalonate pathway, and then inhibit signal transduction in the Ras/ERK (zeige EPHB2 ELISA Kits) and Ras/Akt (zeige AKT1 ELISA Kits) pathways, thereby inhibiting bFGF (zeige FGF2 ELISA Kits), HGF (zeige HGF ELISA Kits), TGF-beta (zeige TGFB1 ELISA Kits) expression

RASA1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Alternative names and synonyms associated with RASA1

  • vacuolar peduncle (vap) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) Elisa Kit
  • RAS p21 protein activator 1 (Rasa1) Elisa Kit
  • CG9209 Elisa Kit
  • CM-AVM Elisa Kit
  • CMAVM Elisa Kit
  • D-RasGAP Elisa Kit
  • Dmel\\CG9209 Elisa Kit
  • Gap Elisa Kit
  • GAPX Elisa Kit
  • p120GAP Elisa Kit
  • p120RASGAP Elisa Kit
  • PKWS Elisa Kit
  • RAS-GAP Elisa Kit
  • Rasa Elisa Kit
  • RASGAP Elisa Kit

Bezeichner auf Proteinebene für RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
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