4-1BB ligand protein (HIS)

Name: 4-1BB ligand

Hergestellt in: Escherichia Coli (E. coli)

Herkunft (Gen): Human

Konjugat: HIS

Applikation: SDS-PAGE (SDS)

Produktnummer: ABIN667100

Produktbeschreibung

Produktmerkmale: 4-1BB ligand , 71-254aa, Human, His-tagged, Recombinant, E.coli

Format: Liquid

Beschreibung: 4-1BB ligand is a type 2 transmembrane glycoprotein belonging to the TNF superfamily. 4-1BBL is expressed by activated B cells, macrophages, dendritic cells, activated T cells, neurons and astrocytes. The interaction of 4-1BB with 4-1BBL strongly regulates immunity and has been proposed to preferentially control T cell responses based on studies in various murine models of cancer, infectious disease and autoimmune disease. Recombinant human 4-1BB ligand, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Tumor necrosis factor ligand superfamily member 9, TNFSF9, 4-1BBL, CD137L, 4-1BB ligand, 4 1BB L, 4 1BB ligand, 4 1BBL, Cd137l, Cd157l, homolog of mouse 4 1BB L, homolog of mouse 4 1BBL, ILA ligand (TNF related), Ly63l, receptor 4 1BB ligand, Tumor necrosis factor (ligand) superfamily member 9. NCBI no.: NP_003802

Molekulargewicht: 23.8 kDa (222aa), confirmed by MALDI-TOF.

Anwendungen

Konzentration: 1 mg/ml (determined by Bradford assay)

Reinheit: > 95% by SDS - PAGE

Buffer: Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 100mM NaCl, 20% glycerol

Lagerung: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Bilder

4-1BB ligand protein (HIS)