Osteopontin Protein (AA 17-314) (His tag)

Produktnummer ABIN620961

Recombinant Osteopontin-Protein exprimiert in not_set.

Kurzübersicht für Osteopontin Protein (AA 17-314) (His tag) (ABIN620961)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Protein-Typ: Recombinant

Spezies: Human

Wirt: Bitte anfragen

Reinheit: > 90.0 % as determined by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 17-314

Aufreinigungstag / Konjugat: Dieses Osteopontin Protein ist gelabelt mit His tag.

Sequenz: MGSSHHHHHH SSGLVPRGSH RSMIPVKQAD SGSSEEKQLY NKYPDAVATW LNPDPSQKQN LLAPQNAVSS EETNDFKQET LPSKSNESHD HMDDMDDEDD DDHVDSQDSI DSNDSDDVDD TDDSHQSDES HHSDESDELV TDFPTDLPAT EVFTPVVPTV DTYDGRGDSV VYGLRSKSKK FRRPDIQYPD ATDEDITSHM ESEELNGAYK AIPVAQDLNA PSDWDSRGKD SYETSQLDDQ SAETHSHKQS RLYKRKANDE SNEHSDVIDS QELSKVSREF HSHEFHSHED MLVVDPKSKE EDKHLKFRIS HELDSASSEV N.

Produktmerkmale: Recombinant Human Osteopontin

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Osteopontin is supplied in 20mM Tris-HCL buffer pH-7.5, 1mM DTT, 2mM EDTA and 10% glycerol.

Lagerung: 4 °C

Antigendetails

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Andere Bezeichnung: Osteopontin

Hintergrund: Secreted Phosphoprotein-1 Human Recombinant produced in E. coli is single, a non-glycosylated, Polypeptide chain containing 321 AA fragment (17-314) and having a total molecular mass of 36.2 kDa. The SPP1 protein is fused to 20 AA His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: Osteopontin is a glycoprotein that was first identified in osteoblasts and is involved in bone remodeling, immune functions in fibroblasts, macrophages, and lymphocytes during inflammation and wound healing. SPP1 binds tightly to hydroxyapatite. SPP1 forms an integral part of the mineralized matrix. SPP1 is vital to cell-matrix interaction. Secreted Phosphoprotein-1 protects against cardiac ischemia-reperfusion injury via late preconditioning. Expression of both Ostepontin and CD44 in hepatocellular carcinoma is linked with advanced tumor stage and contributes to prognosis information. SPP1 is the most over-expressed gene in intrahepatic cholangiocarcinoma. Secreted Phosphoprotein-1 overexpression is related with interstitial lung diseases. Synonyms: Secreted Phosphoprotein-1, OPN, BNSP, BSPI, ETA-1, MGC110940, SPP-1, Osteopontin, Bone sialoprotein 1, Urinary stone protein, Nephropontin, Uropontin, SPP1.

Pathways: Regulation of Cell Size