BMI1 Protein (AA 1-250, partial) (GST tag)

Produktnummer ABIN7479609

Dieses Recombinant BMI1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für BMI1 Protein (AA 1-250, partial) (GST tag) (ABIN7479609)

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Western Blotting (WB), SDS-PAGE (SDS), ELISA

Reinheit: 95 %

Produktdetails

Proteineigenschaft: AA 1-250, partial

Aufreinigungstag / Konjugat: Dieses BMI1 Protein ist gelabelt mit GST tag.

Sequenz: MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSFCK TCIVRYLETSKYCPICDVQVHKTRPLLNIRSDKTLQDIVY KLVPGLFKNEMKRRRDFYAAHPSADAANGSNEDRGEVADE DKRIITDDEIISLSIEFFDQNRLDRKVNKDKEKSKEEVND KRYLRCPAAMTVMHLRKFLRSKMDIPNTFQIDVMYEEEPL KDYYTLMDIAYIYTWRRNGPLPLKYRVRPTCKRMKISHQR DGLTNAGELE

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 6M guanidine hydrochloride, 20mM Tris

Lagerung: 4 °C

Antigendetails

Target: BMI1 (BMI1 Polycomb Ring Finger Oncogene (BMI1))

Andere Bezeichnung: Polycomb complex protein BMI-1

Hintergrund: Background: Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2. Synonyms: Polycomb group RING finger protein 4 RING finger protein 51.

Molekulargewicht: 56.8 kD

NCBI Accession: NM_005180

UniProt: P35226

Pathways: Zellzyklus, Autophagie