anti-NRF2 (NFE2L2) Antikörper

anti-Nuclear Factor (erythroid-Derived 2)-Like 2 Antikörper (NFE2L2)
Auf finden Sie aktuell 212 Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen NRF2 Kits (50) und NRF2 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 282 NRF2 Produkte verfügbar.
AI194320, NF-E2R2, nfe2l2, NRF2, wu:fc15g09, wu:fj67e03

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Am meisten referenzierte anti-NRF2 Antikörper

  1. Human Polyclonal NRF2 Primary Antibody für IHC (fro), IF (p) - ABIN676673 : Lee, Hsu, Chang, Kuo, Hsu, Pan: Ankaflavin: a natural novel PPAR? agonist upregulates Nrf2 to attenuate methylglyoxal-induced diabetes in vivo. in Free radical biology & medicine 2012 (PubMed)
    Zeige alle 16 Referenzen für 676673

  2. Human Polyclonal NRF2 Primary Antibody für IF (p), IHC (p) - ABIN737271 : Wang, Fang, Huang, Chen, Fan, Wang: The chronic effects of low lead level on the expressions of Nrf2 and Mrp1 of the testes in the rats. in Environmental toxicology and pharmacology 2013 (PubMed)
    Zeige alle 16 Referenzen für 737271

  3. Human Polyclonal NRF2 Primary Antibody für ChIP, ICC - ABIN442777 : Sullivan, Martinez-Garcia, Nguyen, Mullen, Dufour, Sudarshan, Licht, Deberardinis, Chandel: The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling. in Molecular cell 2013 (PubMed)
    Zeige alle 3 Referenzen für 442777

  4. Human Polyclonal NRF2 Primary Antibody für IHC (p), WB - ABIN3043888 : Wang, Du, Duan, Guo, Sun, Liu: Inhibiting heme oxygenase-1 attenuates rat liver fibrosis by removing iron accumulation. in World journal of gastroenterology : WJG 2013 (PubMed)
    Zeige alle 2 Referenzen für 3043888

  5. Human Polyclonal NRF2 Primary Antibody für IHC, ELISA - ABIN1584873 : Bagul, Middela, Matapally, Padiya, Bastia, Madhusudana, Reddy, Chakravarty, Banerjee: Attenuation of insulin resistance, metabolic syndrome and hepatic oxidative stress by resveratrol in fructose-fed rats. in Pharmacological research : the official journal of the Italian Pharmacological Society 2012 (PubMed)
    Zeige alle 2 Referenzen für 1584873

  6. Human Polyclonal NRF2 Primary Antibody für EIA, WB - ABIN359515 : Zhao, Sun, Zhang, Strong, Dash, Kan, Grotta, Aronowski: Transcription factor Nrf2 protects the brain from damage produced by intracerebral hemorrhage. in Stroke; a journal of cerebral circulation 2007 (PubMed)
    Zeige alle 2 Referenzen für 359515

  7. Human Polyclonal NRF2 Primary Antibody für EIA, WB - ABIN359516 : Li, Jang, Na, Cha, Surh: Carbon monoxide produced by heme oxygenase-1 in response to nitrosative stress induces expression of glutamate-cysteine ligase in PC12 cells via activation of phosphatidylinositol 3-kinase and Nrf2 signaling. in The Journal of biological chemistry 2007 (PubMed)
    Zeige alle 2 Referenzen für 359516

  8. Cow (Bovine) Polyclonal NRF2 Primary Antibody für WB - ABIN2780749 : Padmanabhan, Tong, Ohta, Nakamura, Scharlock, Ohtsuji, Kang, Kobayashi, Yokoyama, Yamamoto: Structural basis for defects of Keap1 activity provoked by its point mutations in lung cancer. in Molecular cell 2006 (PubMed)

  9. Human Monoclonal NRF2 Primary Antibody für IHC, ELISA - ABIN1724931 : Sandford, Malhotra, Boezen, Siedlinski, Postma, Wong, Akhabir, He, Connett, Anthonisen, Paré, Biswal: NFE2L2 pathway polymorphisms and lung function decline in chronic obstructive pulmonary disease. in Physiological genomics 2012 (PubMed)

Weitere Antikörper gegen NRF2 Interaktionspartner

Zebrafish Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Interaktionspartner

  1. These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.

  2. we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity

  3. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (zeige AKT1 Antikörper) and JNK (zeige MAPK8 Antikörper)/Nrf2/NQO1 (zeige NQO1 Antikörper) pathway.

  4. Bach1 (zeige BACH1 Antikörper) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (zeige BACH1 Antikörper) inhibition based on its level in each tissue.

  5. The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.

  6. The expression of nrf (zeige NRF1 Antikörper) genes varies temporally throughout development and nrf (zeige NRF1 Antikörper) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (zeige GABPb Antikörper).

  7. oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.

  8. results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles

  9. compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds

  10. Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.

Cow (Bovine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Interaktionspartner

  1. These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (zeige HMOX1 Antikörper) within these cells.

  2. the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.

  3. investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (zeige HMOX1 Antikörper) gene expression in aortic endothelial cells by advanced glycation end products

Pig (Porcine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Interaktionspartner

  1. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease.

  2. The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.

Human Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Interaktionspartner

  1. inflammatory cytokines promoted Nrf2 (zeige GABPA Antikörper) nuclear translocation in psoriatic epidermis, which led to elevated expression of K6, K16 (zeige KRT16 Antikörper), and K17 (zeige KRT17 Antikörper), thus promoting keratinocyte proliferation and contributing to the pathogenesis of psoriasis.

  2. The two compounds were shown to induce apoptosis and inhibit the Nrf2 (zeige GABPA Antikörper)/ARE signaling pathway in Hep3B cells.

  3. Reduced mRNA expression of NFE2L2 is associated with breast cancer.

  4. Data (including data from studies using cells from knockout mice) confirm that the NRF2 (zeige GABPA Antikörper)/HMOX1 (zeige HMOX1 Antikörper) axis is a critical pathway in the hyperglycemic-mediated dysregulation and inflammatory features of chondrocytes in type 2 diabetes-associated osteoarthritis. (NRF2 (zeige GABPA Antikörper) = nuclear factor [erythroid-derived 2]-like 2 protein; HMOX1 (zeige HMOX1 Antikörper) = heme oxygenase (zeige HMOX1 Antikörper) [decycling] 1)

  5. This study demonstrates that Nrf2 (zeige GABPA Antikörper) could be an ideal druggable target in AML (zeige RUNX1 Antikörper), more so to the drugs that function through ROS (zeige ROS1 Antikörper), suggesting the possibility of using Nrf2 (zeige GABPA Antikörper) inhibitors in combination with chemotherapeutic agents to modulate drug resistance in AML (zeige RUNX1 Antikörper).

  6. -rich DNA causes a prolonged increase in mRNA levels of NF-kB and NRF2 (zeige GABPA Antikörper) which lasts 48 and 24 h, respectively.

  7. examination of plant (zeige GABPA Antikörper)ar skin b (zeige KRT16 Antikörper)iopsies from individuals with pachyonychia congenita confirmed the presence of (zeige GABPA Antikörper) high levels of hypophosphorylated NRF2 in lesional tissue

  8. SIRT2 (zeige SIRT2 Antikörper) maintains cellular iron levels by binding to and deacetylating nuclear factor erythroid-derived 2 (zeige NFE2 Antikörper)-related factor 2 (NRF2 (zeige GABPA Antikörper)) on lysines 506 and 508, leading to a reduction in total and nuclear NRF2 (zeige GABPA Antikörper) levels.

  9. basal function of NRF2 (zeige GABPA Antikörper) in colorectal cancer

  10. NRF2 (zeige GABPA Antikörper) is regulated at protein level by proteasomal degradation via KEAP1 (zeige KEAP1 Antikörper). Data suggest that antioxidant-induced up-regulation of NRF2 (zeige GABPA Antikörper) expression (a) overcomes KEAP1 (zeige KEAP1 Antikörper) regulation, (b) activates NRF2 (zeige GABPA Antikörper) translocation to nucleus, and (c) activates antioxidant response element. (NRF2 (zeige GABPA Antikörper) = nuclear factor [erythroid-derived 2]-like 2 protein; KEAP1 (zeige KEAP1 Antikörper) = Kelch-like ECH-associated protein 1 (zeige KEAP1 Antikörper))

Mouse (Murine) Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2) Interaktionspartner

  1. These results suggest that the Keap1 (zeige KEAP1 Antikörper)/Nrf2 axis plays a critical role in NFATc1 (zeige NFATC1 Antikörper) expression and osteoclastogenic progression.

  2. Low NRF2 expression is associated with progression of hepatic fibrosis.

  3. Findings show that NRF2 drives the cell cycle entry and differentiation of long-term hematopoietic stem cells at the expense of their quiescence and maintenance, an effect that appears to be beneficial for prompt recovery from blood loss. Study proposes that the appropriate control of NRF2 activity by KEAP1 (zeige KEAP1 Antikörper) is essential for maintaining HSCs and guarantees their stress-induced regenerative response.

  4. The studies tested the role of Nrf2 during Streptococcus pneumoniae pneumonia and identified Nrf2-dependent genes and pathways in lung tissue and in recruited neutrophils.

  5. results provide mechanistic insight into Nrf2 action in the control of inflammation and cell proliferation through regulation of a proinflammatory cytokine with a key function in various inflammatory diseases

  6. Systemic NRF2 activation by Keap1 (zeige KEAP1 Antikörper) knockdown alleviates multiple-organ inflammation and improves the survival rate of Sf mice.

  7. Hypoactivity of NRF2 in Krt16 (zeige KRT16 Antikörper)-/- footpad skin correlated with decreased levels or activity of upstream NRF2 activators.

  8. Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease. Male mice were more sensitive than females.

  9. This study indicated that MAN can protect osteoblast against oxidative damage by modulation of ERK5 (zeige MAPK7 Antikörper)/Nrf2 signaling, which can be new agent for osteoporosis.

  10. In conclusion, quercetin protected mice from d-galactose-induced cognitive functional impairment and neuronal cell apoptosis via activation of the Nrf2-ARE signaling pathway.

NRF2 (NFE2L2) Antigen-Profil

Beschreibung des Gens

This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NRF2 (NFE2L2)

  • nuclear factor (erythroid-derived 2)-like 2a (nfe2l2a) Antikörper
  • nuclear factor (erythroid-derived 2)-like 2 (nfe2l2) Antikörper
  • nuclear factor (erythroid-derived 2)-like 2 (NFE2L2) Antikörper
  • nuclear factor, erythroid 2-like 2 (NFE2L2) Antikörper
  • nuclear factor, erythroid derived 2, like 2 (Nfe2l2) Antikörper
  • AI194320 Antikörper
  • NF-E2R2 Antikörper
  • nfe2l2 Antikörper
  • NRF2 Antikörper
  • wu:fc15g09 Antikörper
  • wu:fj67e03 Antikörper

Bezeichner auf Proteinebene für NFE2L2

Nrf2a , nuclear factor (erythroid-derived 2)-like 2 , nuclear factor erythroid 2-related factor 2 , ECH , NF-E2-related factor 2 , NFE2-related factor 2 , nuclear factor, erythroid derived 2, like 2 , HEBP1 , nuclear factor erythroid-derived 2-like 2 , nrf2 , nuclear factor erythroid 2-like 2

360149 Danio rerio
444736 Xenopus laevis
396014 Gallus gallus
478813 Canis lupus familiaris
497024 Bos taurus
100516343 Sus scrofa
4780 Homo sapiens
18024 Mus musculus
83619 Rattus norvegicus
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