anti-PDE4D (PDE4D) Antikörper

Bezeichnung:
anti-phosphodiesterase 4D, CAMP-Specific Antikörper (PDE4D)
Auf www.antikoerper-online.de finden Sie aktuell 87 phosphodiesterase 4D, CAMP-Specific (PDE4D) Antikörper von 19 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PDE4D Kits (29) und PDE4D Proteine (8) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 130 PDE4D Produkte verfügbar.
Synonyme:
9630011N22Rik, ACRDYS2, DPDE3, HSPDE4D, PDE4DN2, PDE43, STRK1

Meistgesuchte Reaktivitäten zu anti-PDE4D (PDE4D) Antikörper

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anti-Mouse (Murine) PDE4D Antikörper:

anti-Human PDE4D Antikörper:

anti-Rat (Rattus) PDE4D Antikörper:

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Am meisten referenzierte anti-PDE4D Antikörper

  1. Chicken Polyclonal PDE4D Primary Antibody für WB - ABIN493282 : Houslay, Baillie: The role of ERK2 docking and phosphorylation of PDE4 cAMP phosphodiesterase isoforms in mediating cross-talk between the cAMP and ERK signalling pathways. in Biochemical Society transactions 2003 (PubMed)
    Zeige alle 4 Referenzen für 493282

  2. Mouse (Murine) Polyclonal PDE4D Primary Antibody für IP, WB - ABIN493288 : Bolger, Erdogan, Jones, Loughney, Scotland, Hoffmann, Wilkinson, Farrell, Houslay: Characterization of five different proteins produced by alternatively spliced mRNAs from the human cAMP-specific phosphodiesterase PDE4D gene. in The Biochemical journal 1998 (PubMed)
    Zeige alle 4 Referenzen für 493288

  3. Mouse (Murine) Polyclonal PDE4D Primary Antibody für WB - ABIN493298 : Alvarez, Sette, Yang, Eglen, Wilhelm, Shelton, Conti: Activation and selective inhibition of a cyclic AMP-specific phosphodiesterase, PDE-4D3. in Molecular pharmacology 1995 (PubMed)
    Zeige alle 4 Referenzen für 493298

  4. Human Polyclonal PDE4D Primary Antibody für IF, IP - ABIN493279 : Yarwood, Steele, Scotland, Houslay, Bolger: The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform. in The Journal of biological chemistry 1999 (PubMed)
    Zeige alle 4 Referenzen für 493279

  5. Human Polyclonal PDE4D Primary Antibody für ELISA, WB - ABIN185530 : Houslay: The long and short of vascular smooth muscle phosphodiesterase-4 as a putative therapeutic target. in Molecular pharmacology 2005 (PubMed)
    Zeige alle 3 Referenzen für 185530

  6. Mouse (Murine) Polyclonal PDE4D Primary Antibody für IHC, WB - ABIN3022337 : Dlaboga, Hajjhussein, ODonnell: Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram. in Brain research 2006 (PubMed)
    Zeige alle 2 Referenzen für 3022337

Weitere Antikörper gegen PDE4D Interaktionspartner

Mouse (Murine) phosphodiesterase 4D, CAMP-Specific (PDE4D) Interaktionspartner

  1. The effect of dobutamine as a positive inotrope is impaired in mice with cecal ligation and puncture-induced sepsis without changes in cardiac beta1-adrenoceptor signaling as a result of cAMP breakdown achieved by upregulated phosphodiesterase 4D

  2. In vivo knockdown of (zeige FN1 Antikörper) PDE4D5 inhibited inflammation at athero-prone sites (zeige TWIST1 Antikörper)

  3. Results indicate that the cyclic AMP (zeige TMPRSS5 Antikörper) (cAMP) increase is caused by the attenuation of phosphodiesterase (PDE (zeige TWIST1 Antikörper)) activity adrenal cortex-derived Y-1 cell line.

  4. The authors demonstrate that the Attention Deficit Disorder with Hyperactivity phenotype depends on a dysregulation of CREB (zeige CREB1 Antikörper) signaling exerted by a kinase-independent PI3Kgamma (zeige PIK3CG Antikörper)-PDE4D interaction in the noradrenergic neurons of the locus coeruleus.

  5. SIK1 (zeige SIK1 Antikörper) serves as a part of a self-regulatory circuit to modulate insulin (zeige INS Antikörper) secretion from pancreatic beta-cells by controlling cAMP concentration through modulation of PDE4D activity.

  6. Cytokine-induced iNOS (zeige NOS2 Antikörper) and ERK1/2 (zeige MAPK1/3 Antikörper) inhibit adenylyl cyclase type 5/6 activity and stimulate phosphodiesterase 4D5 activity in intestinal longitudinal smooth muscle, contributing to colonic dysmotility during inflammation.

  7. the loss of function of either DISC1 (zeige DISC1 Antikörper) or ATF4 (zeige ATF4 Antikörper) increases PDE4D9 transcription, and the association of DISC1 (zeige DISC1 Antikörper) with the PDE4D9 locus requires ATF4 (zeige ATF4 Antikörper)

  8. these results suggest that Pde4d might serve specific biological functions in regulating the development process of the mouse embryo, and that CpG methylation of the Pde4d promoter may play an important role in regulating Pde4d at a transcriptional level.

  9. Calcineurin regulates degradation of phosphodiesterase 3B (zeige PDE3B Antikörper), in addition to phosphodiesterase 4D.

  10. Beta-arrestin-2 (zeige ARRB2 Antikörper) scaffolding of phosphodiesterase PDE4D5 to the plasma membrane was required for TRPV1 (zeige TRPV1 Antikörper) desensitization.

Human phosphodiesterase 4D, CAMP-Specific (PDE4D) Interaktionspartner

  1. High PDE4D expression is associated with melanoma.

  2. cells on fibronectin (zeige FN1 Antikörper) suppressed cAMP via enhanced phosphodiesterase (PDE (zeige ALDH7A1 Antikörper)) activity, through direct binding of integrin alpha5 to phosphodiesterase-4D5

  3. we performed a meta-analysis of 15 studies, involving 8731 IS patients and 10,756 controls. The results showed nonsignificant association between PDE4D SNP56 and IS risk (T vs. A: OR=1.01, 95%CI=0.88-1.15, P=0.90). Similarly, in the subgroup analysis by ethnicity, no significant association was observed in Asian (T vs. A: OR=1.08, 95%CI=0.80-1.44, P=0.62) or European (T vs. A: OR=0.96, 95%CI=0.86-1.08, P=0.54) population.

  4. RACK1 (zeige GNB2L1 Antikörper) and beta-arrestin2 (zeige ARRB2 Antikörper) inhibit the dimerization of PDE4D5.

  5. PDE4D acts to allow cAMP-elevating agents to regulate VECADs' role as a sensor of flow-associated fluid shear stress (FSS)-encoded information in arterial endothelial cells.

  6. PDE4D gene polymorphisms influence the susceptibility for the development of Sudden Sensorineural Hearing Loss in the southern Taiwanese female population.

  7. focus on recent progress made in PDE4D gene research involving genetic and molecular aspects (review)

  8. No association was found between single-nucleotide polymorphisms of ALOX5AP (zeige ALOX5AP Antikörper) or PDE4D and the risk of overall ischemic stroke in a southeastern Chinese population.

  9. While prior studies have found an association between PDE4D and IL6R (zeige IL6R Antikörper) polymorphisms and ischemic stroke, the results of this study suggest that this association may be different in a hypertensive population.

  10. This review show PDE4D mutation is a risk factor for atrial fibrillation and stroke.

Cow (Bovine) phosphodiesterase 4D, CAMP-Specific (PDE4D) Interaktionspartner

  1. demonstrate the presence of PDE4D transcript and protein, but also show an active enzyme, suggesting a functional role of PDE4D in bovine mammary gland

PDE4D Antigen-Profil

Beschreibung des Gens

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.

Alternative names and synonyms associated with PDE4D

  • phosphodiesterase 4D, cAMP-specific (PDE4D) Antikörper
  • phosphodiesterase 4D, cAMP-specific (pde4d) Antikörper
  • phosphodiesterase 4D, cAMP specific (Pde4d) Antikörper
  • phosphodiesterase 4D, cAMP-specific (Pde4d) Antikörper
  • 9630011N22Rik Antikörper
  • ACRDYS2 Antikörper
  • DPDE3 Antikörper
  • HSPDE4D Antikörper
  • PDE4DN2 Antikörper
  • PDE43 Antikörper
  • STRK1 Antikörper

Bezeichner auf Proteinebene für PDE4D

phosphodiesterase E3 dunce homolog, Drosophila , phosphodiesterase 4D, cAMP-specific , cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like , phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila) , cAMP-specific 3',5'-cyclic phosphodiesterase 4D , cAMP-specific phosphodiesterase 4D , cyclic AMP specific phosphodiesterase PDE4D5A , dunce , cAMP-specific phosphodiesterase PDE4D6 , DPDE3 , Phosphodiesterase 4D cAMP-specific (dunce , Phosphodiesterase 4D, cAMP-specific (dunce , cAMP-specific phosphodiesterase PDE4D , cAMP-specific phosphodiesterase splice variant PDE4D8 , phosphodiesterase 4D, cAMP specific , hypothetical protein

GENE ID SPEZIES
100051344 Equus caballus
100032166 Monodelphis domestica
100406670 Callithrix jacchus
100496479 Xenopus (Silurana) tropicalis
100587050 Nomascus leucogenys
238871 Mus musculus
100302668 Cavia porcellus
5144 Homo sapiens
24627 Rattus norvegicus
769469 Gallus gallus
487221 Canis lupus familiaris
539556 Bos taurus
100351753 Oryctolagus cuniculus
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