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PARP1 (PARP1) ELISA Kits

Bezeichnung:
Poly (ADP-Ribose) Polymerase 1 ELISA Kits (PARP1)
Auf www.antikoerper-online.de finden Sie aktuell 30 Poly (ADP-Ribose) Polymerase 1 (PARP1) ELISA Kits von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen PARP1 Antikörper (407) und PARP1 Proteine (29) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 494 PARP1 Produkte verfügbar.
Synonyme:
5830444G22Rik, Adprp, Adprt, ADPRT 1, Adprt1, AI893648, ARTD1, BEST:LD21673, C80510, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, dPARP, LD21673.3prime, padprt-1, parp, parp-1, PARP1, ppol, sPARP-1

Weitere ELISA Kits für PARP1 Interaktionspartner

Fruit Fly (Drosophila melanogaster) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. The results demonstrate that PARylation process in Drosophila is tightly regulated in the context of strands-breaks repair; PARP is essential during the maintenance of DNA integrity, but dispensable in the DNA repair process.

  2. A mutation of Parp also increases NAD+ levels; although, this was only observed in parkin (zeige PARK2 ELISA Kits) mutant flies and not in the heterozygous Parp mutants, possibly owing to an increased PARP activity in the parkin (zeige PARK2 ELISA Kits) mutants.

  3. chromatin loosening and associated initiation of gene expression is activated by phosphorylation of H2Av (zeige H2AFV ELISA Kits) in a nucleosome positioned in promoter regions of PARP-1-dependent genes

  4. Based on these findings, we propose a model that explains how PARP1 activity impacts nucleolar functions and, consequently, ribosomal biogenesis

  5. PARP is associated with the 5' end of Hsp70, and its enzymatic activity is rapidly induced by heat shock leading to nucleosome loss.

  6. Activation of PARP-1 overexpression in the imago results in extension of the lifespan in females and males. The lifespan increase in females with PARP-1 conditional overexpression was accompanied by decrease of fertility.

  7. PARP1 is targeted to chromatin by association with the histone H2A variant (H2Av).

  8. demonstrate that this alteration specifically excludes PARP1 protein from heterochromatin and makes PARP1 unable to maintain repression of retrotransposable elements.

  9. PARP-e autoregulates Parp transcription

  10. propose that chromosomal PARP molecules become activated by developmental or environmental cues and strip nearby chromatin proteins off DNA to generate a puff

Human Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. Data provide evidence that the acetylation of H2AX (zeige H2AFX ELISA Kits) at Lys5 (zeige AASDHPPT ELISA Kits) by TIP60 (zeige KAT5 ELISA Kits) is required for the (ADPribosyl) ation activity and the dynamic binding of PARP-1 to chromatin after the induction of DNA damage.

  2. H. pylori-infected gastric mucosa had increased alternative non-homologous end joining, implicating that telomere shortening was caused by inflammation-mediated overproduction of reactive oxygen species and PARP-1, leading to telomere shortening

  3. In summary, the authors identified a novel mechanism by which human herpesvirus 4 LMP1 (zeige PDLIM7 ELISA Kits) drives expression of host tumor-promoting genes by blocking generation of the inhibitory histone modification H3K27me3 through PARP1 activation.

  4. immunohistochemical BRCA1 expression in epithelial ovarian cancer holds considerable prognostic information, whereas PARP (zeige COL11A2 ELISA Kits) expression did not influence the outcome

  5. A series of poly(ADP-ribose)polymerase (PARP)-1 inhibitors containing a novel scaffold, the 1H-thieno[3,4-d]imidazole-4-carboxamide moiety, was designed and synthesized

  6. data establish the importance of XRCC1 (zeige XRCC1 ELISA Kits) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  7. Ubc9 (zeige UBE2I ELISA Kits) plays different roles of action in antitumor agents in chemotherapy. The process requires bleomycin hydrolase (zeige BLMH ELISA Kits) and poly(ADP-ribose) polymerase-1. The results are beneficial to deeply understanding of Ubc9 (zeige UBE2I ELISA Kits) functions and for precise prediction of chemotherapy outcomes in tumors.

  8. Data show that the apoptotic and cytotoxic effects of BL-038 are mediated by the intrinsic mitochondria-mediated apoptotic pathway, which in turn causes the activation of caspase-9 (zeige CASP9 ELISA Kits) and caspase-3 (zeige CASP3 ELISA Kits), and the cleavage of poly (ADP-ribose) polymerase (PARP), to elicit apoptosis response.

  9. knockdown of PARP-1 inhibits cell growth and increases sensitivity of U2OS cells to cisplatin, with the increasing drug sensitivity possibly associated with the inhibition of ERK (zeige EPHB2 ELISA Kits) signals.

  10. high PARP1 expression may represent a marker of poorer prognosis both for patients with worse clinical outcome and in less aggressive clinical conditions.

Cow (Bovine) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. no difference was found in the level of SBDP145 between muscles, while SBDP120 and PARP-1 cleavage products were not detected

  2. ADPRT Val762Ala and APE1 (zeige APEX1 ELISA Kits) Asp148Glu polymorphisms are not associated with increased breast cancer risk

  3. analysis of poly(ADP-ribose) polymerase 1 interaction with apurinic/apyrimidinic sites

  4. FGF2 (zeige FGF2 ELISA Kits) stimulates poly(ADP-ribose) polymerase activity by a DNA strand breaks-independent manner which involves a mitogen-activated protein kinases (MAPK (zeige MAPK1 ELISA Kits))-dependent pathway

Mouse (Murine) Poly (ADP-Ribose) Polymerase 1 (PARP1) Interaktionspartner

  1. Delayed healing in ischemic and diabetic wounds is caused by PARP hyperactivity, and PARP inhibition significantly enhanced ischemic and diabetic wound healing by promoting angiogenesis.

  2. The findings highlight specific non-overlapping functions of PARP1 and PARP2 (zeige PARP2 ELISA Kits) at H2AX (zeige H2AFX ELISA Kits)-deficient chromatin during replicative phases of the cell cycle and uncover a unique requirement for PARP1 in nonhomologous end-joining-deficient cells.

  3. data establish the importance of XRCC1 (zeige XRCC1 ELISA Kits) protein complexes for normal neurological function and identify PARP1 as a therapeutic target in DNA strand break repair-defective disease

  4. this study shows that PARP-1 inhibition plays role in puerarin-mediated protection from liver fibrosis

  5. might be involved in streptomycin ototoxicity by regulating AIF (zeige AIFM1 ELISA Kits) translocation in cochlear hair cells

  6. Nonionizing radiofrequency exposure is capable of inducing PARP-1.

  7. our data suggest that Parp1 is involved in the plastic remodeling of chromatin structure after NT by supporting DNA repair and specific histone code modifications.

  8. ARTD1 controls osteoclast development and bone remodelling via its enzymatic activity by modulating the epigenetic marks surrounding the IL-1beta (zeige IL1B ELISA Kits) promoter and expression of IL-1beta (zeige IL1B ELISA Kits) and subsequently also Nfatc1 (zeige NFATC1 ELISA Kits)/A.

  9. the role of PARP-1 in age-dependent changes in endothelial cell function and its underlying mechanism

  10. Both depletion of PARP-1 and inhibition of PARP-1 activity augmented LXR (zeige NR1H3 ELISA Kits) ligand-induced ABCA1 (zeige ABCA1 ELISA Kits) expression in the RAW 264.7 macrophage line and primary bone marrow-derived macrophages but did not affect LXR (zeige NR1H3 ELISA Kits)-dependent expression of other target genes, ABCG1 (zeige ABCG1 ELISA Kits) and SREBP-1c (zeige SREBF1 ELISA Kits).

PARP1 Antigen-Profil

Beschreibung des Gens

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Alternative names and synonyms associated with PARP1

  • Poly-(ADP-ribose) polymerase (Parp) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (PARP1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (Parp1) Elisa Kit
  • poly (ADP-ribose) polymerase 1 (parp1) Elisa Kit
  • poly (ADP-ribose) polymerase family, member 1 (Parp1) Elisa Kit
  • poly ADP-ribose polymerase (Parp) Elisa Kit
  • 5830444G22Rik Elisa Kit
  • Adprp Elisa Kit
  • Adprt Elisa Kit
  • ADPRT 1 Elisa Kit
  • Adprt1 Elisa Kit
  • AI893648 Elisa Kit
  • ARTD1 Elisa Kit
  • BEST:LD21673 Elisa Kit
  • C80510 Elisa Kit
  • CG17685 Elisa Kit
  • CG17696 Elisa Kit
  • CG17718 Elisa Kit
  • CG40411 Elisa Kit
  • D.PARP Elisa Kit
  • Dm.pARTa Elisa Kit
  • Dmel\\CG40411 Elisa Kit
  • dPARP Elisa Kit
  • LD21673.3prime Elisa Kit
  • padprt-1 Elisa Kit
  • parp Elisa Kit
  • parp-1 Elisa Kit
  • PARP1 Elisa Kit
  • ppol Elisa Kit
  • sPARP-1 Elisa Kit

Bezeichner auf Proteinebene für PARP1

CG40411-PB , CG40411-PC , Parp-PB , Parp-PC , Poly(ADP ribose) polymerase 1 , Poly(ADP)-Ribose polymerase , Poly(ADP-)Ribose polymerase , Poly(ADP-ribose) polymerase , Poly(ADP-ribose) polymerase 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) , ADP-ribosyltransferase NAD(+) , ADP-ribosyltransferase diphtheria toxin-like 1 , NAD(+) ADP-ribosyltransferase 1 , poly (ADP-ribose) polymerase family, member 1 , poly [ADP-ribose] polymerase 1 , poly(ADP-ribose) polymerase , poly(ADP-ribose) synthetase , poly(ADP-ribosyl)transferase , poly[ADP-ribose] synthase 1 , ADP-ribosyltransferase (NAD+ , ADP-ribosyltransferase 1 , ADPRT 1 , poly (ADP-ribose) polymerase) , poly(ADP-ribose) polymerase PARP-1 , poly[ADP-ribose] synthetase 1 , ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase) , PARP-1 , ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1 , ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1 , msPARP , Poly[ADP-ribose] synthase 1

GENE ID SPEZIES
3355109 Drosophila melanogaster
142 Homo sapiens
25591 Rattus norvegicus
286764 Bos taurus
397928 Xenopus laevis
396199 Gallus gallus
490385 Canis lupus familiaris
11545 Mus musculus
100689463 Cricetulus griseus
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