ERBB4 Antikörper (pTyr1242)
Kurzübersicht für ERBB4 Antikörper (pTyr1242) (ABIN126796)
Target
Alle ERBB4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pTyr1242
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Spezifität
- This antibody specifically recognizes erbB4 phosphorylated on Tyr 1242 at 180 kDa.
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Produktmerkmale
- Synonyms: p180erbB4, c-ErbB-4, HER-4, Receptor tyrosine-protein kinase erbB-4, Proto-oncogene-likeprotein c-ErbB-4, Tyrosine kinase-type cell surface receptor HER4
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Aufreinigung
- Size exclusion chromatography
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Bestandteile
- incl. positive Control
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Immunogen
- Phosphopeptide conjugated to hemocyanin
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Isotyp
- IgG
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anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 29-278) antibody
ERBB4 Reaktivität: Human WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1284) antibodyERBB4 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (C-Term) antibodyERBB4 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1159-1308) antibodyERBB4 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 5G6B4 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reaktivität: Human IHC Wirt: Maus Monoclonal ERBB4-2581 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB5687 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (pTyr1162) antibodyERBB4 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1116-1269) antibodyERBB4 Reaktivität: Human, Maus IF, FACS Wirt: Maus Monoclonal HFR-1 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 1159-1308) antibodyERBB4 Reaktivität: Human ELISA, FACS, ICC Wirt: Maus Monoclonal 4E7G5 unconjugated
anti-V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4) (AA 25-55), (N-Term) antibodyERBB4 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01469 unconjugated
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Applikationshinweise
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Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Protokoll
- Positive control: Cell lysate from EGF-treated MDA-MB 468 cellsFormulationLyophilized cell lysate from MDA-MB-468 cells. Serum starved cells were treated for 15 min with EGF.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.1 mg/mL
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Buffer
- PBS/0.09 % Na-Azide/PEG and Sucrose/50 % Glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
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Store the antibody (in aliquot) at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Haltbarkeit
- 12 months
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- ERBB4 (V-Erb-A erythroblastic Leukemia Viral Oncogene Homolog 4 (Avian) (ERBB4))
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Andere Bezeichnung
- ERBB4 / HER4
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Hintergrund
- ErbB4/Her4 is a member of the receptor tyrosine kinase subfamily that includes EGFR, erbB2/her2, and erbB3/Her3. erbB4 is a receptor for Neuregulin 1 (NRG1) and regulates cell proliferation and differentiation. Tyr 1242 is a potential SHC binding site which leads to MAPK signalling pathway.Synonyms: HER-4, Proto-oncogene-like protein c-ErbB-4, Receptor tyrosine-protein kinase erbB-4, Tyrosine kinase-type cell surface receptor HER4, c-ErbB-4, p180erbB4
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Gen-ID
- 2066
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UniProt
- Q15303
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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