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VASP Antikörper (AA 248-379)

VASP Reaktivität: Human, Hund WB, IHC, IF, IP Wirt: Maus Monoclonal 43-VASP unconjugated
Produktnummer ABIN967977
  • Target Alle VASP Antikörper anzeigen
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    Bindungsspezifität
    • 19
    • 17
    • 15
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 248-379
    Reaktivität
    • 137
    • 65
    • 58
    • 11
    • 11
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Hund
    Wirt
    • 116
    • 20
    • 2
    Maus
    Klonalität
    • 111
    • 27
    Monoklonal
    Konjugat
    • 80
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VASP Antikörper ist unkonjugiert
    Applikation
    • 105
    • 51
    • 49
    • 27
    • 22
    • 17
    • 14
    • 14
    • 12
    • 11
    • 5
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
    Kreuzreaktivität
    Hund
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human VASP aa. 248 - 379
    Klon
    43-VASP
    Isotyp
    IgG1
    Top Product
    Discover our top product VASP Primärantikörper
  • Kommentare

    Related Products: ABIN968536

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20° C.
  • DeMali, Barlow, Burridge: "Recruitment of the Arp2/3 complex to vinculin: coupling membrane protrusion to matrix adhesion." in: The Journal of cell biology, Vol. 159, Issue 5, pp. 881-91, (2002) (PubMed).

    Howe, Hogan, Juliano: "Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion." in: The Journal of biological chemistry, Vol. 277, Issue 41, pp. 38121-6, (2002) (PubMed).

    Lawrence, Pryzwansky: "The vasodilator-stimulated phosphoprotein is regulated by cyclic GMP-dependent protein kinase during neutrophil spreading." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 9, pp. 5550-6, (2001) (PubMed).

    Haffner, Jarchau, Reinhard, Hoppe, Lohmann, Walter: "Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP." in: The EMBO journal, Vol. 14, Issue 1, pp. 19-27, (1995) (PubMed).

    Reinhard, Giehl, Abel, Haffner, Jarchau, Hoppe, Jockusch, Walter: "The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins." in: The EMBO journal, Vol. 14, Issue 8, pp. 1583-9, (1995) (PubMed).

  • Target
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    Andere Bezeichnung
    VASP (VASP Produkte)
    Synonyme
    vasp antikoerper, MGC80889 antikoerper, wu:fb23b04 antikoerper, wu:fk84g05 antikoerper, zgc:110347 antikoerper, si:dkey-113g17.1 antikoerper, si:ch211-202c21.1 antikoerper, DDBDRAFT_0188463 antikoerper, DDBDRAFT_0229340 antikoerper, DDB_0188463 antikoerper, DDB_0229340 antikoerper, VASP antikoerper, vasodilator stimulated phosphoprotein S homeolog antikoerper, vasodilator stimulated phosphoprotein b antikoerper, protein enabled antikoerper, vasodilator-stimulated phosphoprotein antikoerper, vasodilator stimulated phosphoprotein a antikoerper, vasodilator stimulated phosphoprotein antikoerper, vasp.S antikoerper, vaspb antikoerper, LOC5573842 antikoerper, CpipJ_CPIJ004706 antikoerper, CpipJ_CPIJ004707 antikoerper, vasP antikoerper, vasp antikoerper, VASP antikoerper, vaspa antikoerper, Vasp antikoerper
    Hintergrund
    Vasodilator-stimulated phosphoprotein (VASP), a substrate for cAMP- and cGMP-dependent kinases, is associated with actin filaments, focal adhesions, and dynamic membrane regions. VASP is composed of several distinct domains: a central L-proline-rich domain contains a GPPPPP motif as a single copy and as a three-fold tandem repeat, as well as three conserved phosphorylation sites for cyclic nucleotide-dependent protein kinases (Ser157, Ser239, and Thr278). A C-terminal domain contains a repetitive mixed-charge cluster which is predicted to form an alpha-helix. The C-terminal domain appears to be responsible for anchoring at focal adhesion sites. VASP has been shown to be a ligand for profilins. Profilins bind to the poly-L-proline motifs of VASP and it is postulated that these two molecules act in concert to convey signal transduction to actin filament formation.
    Molekulargewicht
    46 kDa
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation
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