Integrin Alpha2b Antikörper (Biotin)
(1 reference)Kurzübersicht für Integrin Alpha2b Antikörper (Biotin) (ABIN94107)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Anti-Hu CD41 Biotin
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Kreuzreaktivität (Details)
- Human
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Produktmerkmale
- The antibody MEM-06 reacts with an extracellular epitope of CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 kDa) and GPIIb beta (light chain, 23 kDa). CD41 is mainly expressed on platelets and megakaryocytes.
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Aufreinigung
- Purified antibody is conjugated with biotin LC-NHS ester under optimum conditions and unconjugated antibody and free biotin are removed by size-exclusion chromatography.
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Immunogen
- Leukocytes of patient suffering from LGL-type leukaemia.
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Isotyp
- IgG1
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anti-Integrin Alpha2b (CD41) (AA 45-149) antibody
CD41 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 2E10C9 unconjugated
anti-Integrin Alpha2b (CD41) (AA 45-149) antibodyCD41 Reaktivität: Human FACS, WB, IHC, ELISA Wirt: Maus Monoclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 351-450) antibodyCD41 Reaktivität: Human, Ratte FACS, WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (AA 677-711), (C-Term) antibodyCD41 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p) Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Maus FACS, ELISA, IP, IHC (fro), IHC (p), Func Wirt: Ratte Monoclonal MWReg30 unconjugated
anti-Integrin Alpha2b (CD41) antibody (FITC)CD41 Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-06 FITC
anti-Integrin Alpha2b (CD41) antibodyCD41 Reaktivität: Human, Non-Human Primate FACS, IHC (fro) Wirt: Maus Monoclonal HIP2 unconjugated
anti-Integrin Alpha2b (CD41) (AA 122-171) antibodyCD41 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin Alpha2b (CD41) (Internal Region) antibodyCD41 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Flow cytometry: Recommended dilution: 2 μg/mL.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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: "Tetraspanins distinguish separate extracellular vesicle subpopulations in human serum and plasma - Contributions of platelet extracellular vesicles in plasma samples." in: Journal of extracellular vesicles, Vol. 11, Issue 5, pp. e12213, (2022) (PubMed).
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
- CD41
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Hintergrund
- Integrin subunit alpha 2b,CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, alpha and 23 kDa b, beta) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.,Platelet GPIIb, Integrin alpha-IIb, GPalpha IIb, GTA
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Gen-ID
- 3674
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UniProt
- P08514
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Pathways
- Integrin Complex
Target
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