Adenylosuccinate Lyase Antikörper (Middle Region)

Produktnummer ABIN929409

Der Kaninchen Polyklonal anti-Adenylosuccinate Lyase Antikörper (ABIN929409) detektiert spezifisch Adenylosuccinate Lyase in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Adenylosuccinate Lyase Antikörper (Middle Region) (ABIN929409)

Target: Adenylosuccinate Lyase (ADSL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenylosuccinate Lyase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Adenylosuccinate Lyase Antikörper

Bindungsspezifität: Middle Region

Aufreinigung: Purified

Immunogen: ADSL antibody was raised in rabbit using the middle region of ADSL as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

ADSL Blocking Peptide, (ABIN5611964), is also available for use as a blocking control in assays to test for specificity of this ADSL antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Adenylosuccinate Lyase

Target: Adenylosuccinate Lyase (ADSL)

Andere Bezeichnung: ADSL

Hintergrund: Adenylsuccinate lyase is involved in both de novo synthesis of purines and formation of adenosine monophosphate from inosine monophosphate. It catalyzes two reactions in AMP biosynthesis: the removal of a fumarate from succinylaminoimidazole carboxamide (SAICA) ribotide to give aminoimidazole carboxamide ribotide (AICA) and removal of fumarate from adenylosuccinate to give AMP. Adenylosuccinase deficiency results in succinylpurinemic autism, psychomotor retardation, and , in some cases, growth retardation associated with muscle wasting and epilepsy. Two transcript variants encoding different isoforms have been found for this gene. Synonyms: Polyclonal ADSL antibody, Anti-ADSL antibody, adenylosuccinate lyase antibody, AMPS antibody, ASASE antibody, ASL antibody.

Pathways: Ribonucleoside Biosynthetic Process