HDAC3 Antikörper (C-Term)

Produktnummer ABIN928003

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HDAC3 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für HDAC3 Antikörper (C-Term) (ABIN928003)

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HDAC3 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Purified

Immunogen: Hdac3 antibody was raised in rabbit using the C terminal of Hdac3 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

Hdac3 Blocking Peptide, (ABIN937608), is also available for use as a blocking control in assays to test for specificity of this Hdac3 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu HDAC3

Target: HDAC3 (Histone Deacetylase 3 (HDAC3))

Andere Bezeichnung: Hdac3

Hintergrund: Hdac3 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.Hdac3 is required to repress transcription of the POU1F1 transcription factor. Hdac3 acts as a molecular chaperone for shuttling phosphorylated NR2C1 to PML bodies for sumoylation. Synonyms: Polyclonal Hdac3 antibody, Anti-Hdac3 antibody, histone deacetylase 3 antibody, Hdac3 antibody.

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development