WNT2B Antikörper (Middle Region)

Produktnummer ABIN785147

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-WNT2B Antikörper wird verwendet zum Nachweis von WNT2B in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für WNT2B Antikörper (Middle Region) (ABIN785147)

Target: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-WNT2B Antikörper

Bindungsspezifität: Middle Region

Sequenz: LRTCWRALSD FRRTGDYLRR RYDGAVQVMA TQDGANFTAA RQGYRRATRT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WNT2B. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human WNT2B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 372 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WNT2B Antikörper (ABIN785147)

Chigita, Sugiura, Abe, Kobayashi, Shimoda, Onoda, Shirasuna: "CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of ?-catenin in carcinoma cells." in: International journal of oncology, Vol. 41, Issue 6, pp. 2021-8, (2012) (PubMed).

Details zu WNT2B

Target: WNT2B (Wingless-Type MMTV Integration Site Family, Member 2B (WNT2B))

Andere Bezeichnung: WNT2B

Hintergrund: WNT2B is a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as human carcinogenesis. This gene produces two alternative transcript variants.
Alias Symbols: WNT13, XWNT2
Protein Interaction Partner: RAD21, BRCA1,
Protein Size: 372

Molekulargewicht: 41 kDa

Gen-ID: 7482

NCBI Accession: NM_004185, NP_004176

UniProt: Q5T6U1

Pathways: WNT Signalweg