SLC39A5 Antikörper (Center)

Produktnummer ABIN783803

Der Kaninchen Polyklonal anti-SLC39A5 Antikörper wird verwendet zum Nachweis von SLC39A5 in Proben von Human und Maus. Er wurde validiert für WB und EIA.

Kurzübersicht für SLC39A5 Antikörper (Center) (ABIN783803)

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SLC39A5 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects Zinc transporter ZIP5 / SLC39A5 at Center.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 17 amino acid peptide near the center of human ZIP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu SLC39A5

Target: SLC39A5 (Solute Carrier Family 39 (Metal Ion Transporter), Member 5 (SLC39A5))

Andere Bezeichnung: Zinc Transporter ZIP5 / SLC39A5

Hintergrund: The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.Synonyms: Solute carrier family 39 member 5, ZIP-5, ZIP5, Zrt- and Irt-like protein 5

Gen-ID: 283375

NCBI Accession: NP_001128667

UniProt: Q6ZMH5

Pathways: Transition Metal Ion Homeostasis