FasL (CD178) Antikörper

Antigen: FasL (CD178)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Ratte (Rattus), Maus, Rind (Kuh)

Applikation: Western Blot (WB), ELISA, Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)), Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN726410

Produktbeschreibung

Weitere Bezeichnung: FasL

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human FasL C-terminus

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Synonym: APO1L, Apoptosis (APO 1) antigen ligand 1, Apoptosis antigen ligand 1, APTL, CD178, CD178, CD95L, CD95L protein, FAS antigen ligand, Fas L, Fas Ligand, FASL, Fasl Fas ligand (TNF superfamily member 6), Generalized lymphoproliferative disease, TNF superfamily member 6, TNFSF6, Tumor necrosis factor ligand superfamily member 6.

Molekulargewicht: 36-43kDa

Kommentare:

FasL (CD95L) is a cytokine that binds to TNFRSF6/FAS

a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance

in the antigen-stimulated suicide of mature T cells

or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. Homotrimer (Probable). May be released as type II membrane protein. Belongs to the tumor necrosis factor family

Anwendungen

Applikationshinweise: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Forschungsgebiet: CD Antigene, Oberflächenrezeptoren der Immunzellen , Apoptose/Nekrose, Virologie, Krebs

Beschränkungen: Nur für Forschungszwecke einsetzbar