SCN8A Antikörper (AA 251-314)

Produktnummer ABIN719981

Der Kaninchen Polyklonal anti-SCN8A Antikörper wird verwendet zum Nachweis von SCN8A in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IF (cc), IF (p), IHC (fro) und IHC (p).

Kurzübersicht für SCN8A Antikörper (AA 251-314) (ABIN719981)

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCN8A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SCN8A Antikörper

Bindungsspezifität: AA 251-314

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCN8A/Nav1.6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu SCN8A

Target: SCN8A (Sodium Channel, Voltage-Gated, Type VIII, alpha (SCN8A))

Andere Bezeichnung: SCN8A

Hintergrund:

Synonyms: CerIII, hNa6/Scn8a voltage gated sodium channel, MED, Motor endplate disease, NaCh 6, NaCh6, Nav 1.6, Nbna1, PN 4, PN4, Scn8a, SCN8A_HUMAN, Sodium channel protein type 8 alpha subunit, Sodium channel protein type 8 subunit alpha, Sodium channel protein type VIII alpha subunit, Sodium channel protein type VIII subunit alpha, Sodium channel voltage gated type VIII alpha, Sodium channel voltage gated type VIII alpha polypeptide, Sodium channel voltage gated type VIII alpha subunit, Voltage gated sodium channel subunit alpha Nav1.6, Voltage-gated sodium channel subunit alpha Nav1.6.

Background: Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.

Gen-ID: 6334

Pathways: Sensory Perception of Sound