BAK1 Antikörper (AA 21-120)

Produktnummer ABIN674409

Zitiert in 3+ Publikationen. Der Kaninchen Polyklonal anti-BAK1 Antikörper (ABIN674409) detektiert spezifisch BAK1 in WB, ELISA, FACS, IHC (p), IF (cc), IF (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte und Huhn.

Kurzübersicht für BAK1 Antikörper (AA 21-120) (ABIN674409)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BAK1 Antikörper

Bindungsspezifität: AA 21-120

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse BAK

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-BAK1 Antikörper (ABIN674409)

Yang, Pei, Zhang, Liao, Yu, Qiao, Han, Li, Hu, Guo, Pan, Tang: "Copper induces oxidative stress and apoptosis through mitochondria-mediated pathway in chicken hepatocytes." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 54, pp. 310-316, (2019) (PubMed).

Huang, Chao, Lee, Lu, Cheng, Yang, Wang, Chang, Huang: "Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane Permeability." in: Molecular neurobiology, (2015) (PubMed).

Zhu, Wang, Liang, Wang, Zhang, Li, Ying: "Regulation of cell transformation by Rb-controlled redox homeostasis." in: PLoS ONE, Vol. 9, Issue 7, pp. e102582, (2014) (PubMed).

Details zu BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Andere Bezeichnung: BAK

Hintergrund:

Synonyms: Apoptosis Regulator Bak, BAK 1, BAK, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK, BAX_MOUSE.

Background: In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.

Gen-ID: 12018

UniProt: O08734

Pathways: Apoptose, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response