26S proteasome non-ATPase regulatory subunit 11 Antikörper (Biotin)

Antigen: 26S proteasome non-ATPase regulatory subunit 11

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus), Hund, Zebrafisch (Danio rerio)

Konjugat: Biotin

Applikation: Western Blot (WB), ELISA

Zertifikate: ISO 9001:2008

Produktnummer: ABIN618283

Produktbeschreibung

Immunogen: Recombinant human 26S proteasome non-ATPase regulatory subunit 11 protein

Format: Liquid

Isotyp: IgG

Beschreibung: Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Synonyms: 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit p44.5.

Anwendungen

Reinheit: CA-AS

Buffer: PBS

Lagerung: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.

Beschränkungen: Nur für Forschungszwecke einsetzbar