TCF7L2 Antikörper (AA 1-455)

Produktnummer ABIN520776

Zitiert in 2+ Publikationen. Der Maus Monoklonal anti-TCF7L2 Antikörper (Klon 1A9) (ABIN520776) detektiert spezifisch TCF7L2 in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TCF7L2 Antikörper (AA 1-455) (ABIN520776)

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCF7L2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1A9

Produktdetails anti-TCF7L2 Antikörper

Bindungsspezifität: AA 1-455

Verwendungszweck: Mouse monoclonal antibody raised against a full length recombinant TCF7L2.

Sequenz: MPQLNGGGGD DLGANDELIS FKDEGEQEEK SSENSSAERD LADVKSSLVN ESETNQNSSS DSEAERRPPP RSESFRDKSR ESLEEAAKRQ DGGLFKGPPY PGYPFIMIPD LTSPYLPNGS LSPTARTYLQ MKWPLLDVQA GSLQSRQALK DARSPSPAHI VSNKVPVVQH PHHVHPLTPL ITYSNEHFTP GNPPPHLPAD VDPKTGIPRP PHPPDISPYY PLSPGTVGQI PHPLGWQGQP VYPITTGGFR HPYPTALTVN ASMSRFPPHM VPPHHTLHTT GIPHPAIVTP TVKQESSQSD VGSLHSSKHQ DSKKEEEKKK PHIKKPPNAF MLYMKEMRAK VVAECTLKES AAINQILGRR WHALSREEQA KYYELARKER QLHMQLYPGW SARDNYGKKK KRKRDKQPGE TNEHSECFLN PCLSLPPITG EKKSAFATYK VKAAASAHPL QMEAY

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Recombinant Protein.

Immunogen: TCF7L2 (AAH32656, 1 a.a. ~ 455 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1x PBS, pH 7.4

Handhabung: Aliquot to avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-TCF7L2 Antikörper (ABIN520776)

da Silva Xavier, Loder, McDonald, Tarasov, Carzaniga, Kronenberger, Barg, Rutter: "TCF7L2 regulates late events in insulin secretion from pancreatic islet beta-cells." in: Diabetes, Vol. 58, Issue 4, pp. 894-905, (2009) (PubMed).

Fancy, Baranzini, Zhao, Yuk, Irvine, Kaing, Sanai, Franklin, Rowitch: "Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS." in: Genes & development, Vol. 23, Issue 13, pp. 1571-85, (2009) (PubMed).

Details zu TCF7L2

Target: TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))

Andere Bezeichnung: TCF7L2

Hintergrund: Full Gene Name: transcription factor 7-like 2 (T-cell specific, HMG-box)
Synonyms: TCF-4,TCF4

Gen-ID: 6934

Pathways: WNT Signalweg, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus