EIF2B1 Antikörper (C-Term)

Produktnummer ABIN503287

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EIF2B1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh) und Pferd.

Kurzübersicht für EIF2B1 Antikörper (C-Term) (ABIN503287)

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-EIF2B1 Antikörper

Bindungsspezifität: C-Term

Sequenz: ADTLKVAQTG QDLKEEHPWV DYTAPSLITL LFTDLGVLTP SAVSDELIKL

Homologie: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2B1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 305 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Andere Bezeichnung: EIF2B1

Hintergrund: EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
Alias Symbols: EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869
Protein Interaction Partner: RD3, WDYHV1, GORASP2, EIF2B1, UBC, GCD2, GCD6, EIF2B2, STK11, DCC, MRPL4, EIF2S2, EIF2S1, ARL4D, CREBBP, ADRB2, ADRA2B, ADRA2C, ADRA2A, EIF2B5, DCD, PDIA4, EIF2B3, HNRNPL, ARHGDIA,
Protein Size: 305

Molekulargewicht: 34 kDa

Gen-ID: 1967

NCBI Accession: NM_001414, NP_001405

UniProt: Q14232

Pathways: Methionine Biosynthetic Process