POLD2 Antikörper (N-Term)

Produktnummer ABIN502972

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch POLD2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Hund und Pferd.

Kurzübersicht für POLD2 Antikörper (N-Term) (ABIN502972)

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-POLD2 Antikörper

Bindungsspezifität: N-Term

Sequenz: LREVSEEHNL LPQPPRSKYI HPDDELVLED ELQRIKLKGT IDVSKLVTGT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POLD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POLD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 469 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POLD2

Target: POLD2 (Polymerase (DNA Directed), delta 2, Accessory Subunit (POLD2))

Andere Bezeichnung: POLD2

Hintergrund: This protein is a DNA polymerase delta complex ,it involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen, the multisubunit replication factor C, and the 4 subunit polymerase complex: POLD1, POLD2, POLD3, and POLD4The DNA polymerase delta complex is involved in DNA replication and repair, and it consists of the proliferating cell nuclear antigen (PCNA, MIM 176740), the multisubunit replication factor C (see MIM 102579), and the 4 subunit polymerase complex: POLD1 (MIM 174761), POLD2, POLD3 (MIM 611415), and POLD4 (MIM 611525) (Liu and Warbrick, 2006 [PubMed 16934752]).[supplied by OMIM].
Alias Symbols: -
Protein Interaction Partner: UBC, SPRTN, FOXK1, FAM129A, XRN1, POLD1, MMS19, POLD4, CCHCR1, SOX12, EP300, UBD, BBLF2-BBLF3, POLD3, PCNA, POLDIP3, POLDIP2, KCTD13, WRNIP1, LSM6, WRN, CDK2, CDKN1A,
Protein Size: 469

Molekulargewicht: 51 kDa

Gen-ID: 5425

NCBI Accession: NM_006230, NP_006221

UniProt: P49005

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA