FECH Antikörper (Middle Region)

Produktnummer ABIN502157

Der Kaninchen Polyklonal anti-FECH Antikörper wird verwendet zum Nachweis von FECH in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für FECH Antikörper (Middle Region) (ABIN502157)

Target: FECH (Ferrochelatase (FECH))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FECH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FECH Antikörper

Bindungsspezifität: Middle Region

Sequenz: KRSEVVILFS AHSLPMSVVN RGDPYPQEVS ATVQKVMERL EYCNPYRLVW

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FECH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 423 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FECH

Target: FECH (Ferrochelatase (FECH))

Andere Bezeichnung: FECH

Hintergrund: FECH is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EPP, FCE
Protein Interaction Partner: PPP2R1A, UBC, NEDD8, MDM2, FBXO6, gag-pol, COPS5, COPS6, CUL3, ELAVL1, MINOS1, MME, USP42, USP20, ABCB7, FECH,
Protein Size: 423

Molekulargewicht: 42 kDa

Gen-ID: 2235

NCBI Accession: NM_000140, NP_000131

UniProt: P22830

Pathways: Transition Metal Ion Homeostasis