Heat Shock 27kDa Protein 1 (HSPB1) Antikörper

Antigen: Heat Shock 27kDa Protein 1 (HSPB1)

Synonyme: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, MGC147259

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human

Applikation: Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)

Produktnummer: ABIN498626

Produktbeschreibung

Produktmerkmale: Synonyms: Heat shock protein beta-1, Heat shock 27 kDa protein, HSP28, 28 kDa heat shock protein,SRP27, HSP25, Stress-responsive protein 27, Estrogen-regulated 24 kDa protein

Weitere Bezeichnung: HSPB1 / HSP27

Gen-ID: 3315

Swiss-Prot: P04792

Kreuzreaktivität: Human

Beschreibung: Hsp27, also referred to as the Estrogen-Regulated 24K protein and HSP28, is one of severalsmall heat shock proteins (HSP) produced by all organisms studied. Hsp27 synthesis isinduced by elevated temperature, as well as estrogen in hormone responsive cells. Thisprotein is involved in stress resistance and actin organization. Interestingly, human HSP27also shares greater than 50% homology with low molecular weight Drosophila HSP's andmammalian a-crystalline lens protein. Because of the estrogen-responsive nature ofHsp27, this protein has been studied extensively in human estrogen-responsive tissuessuch as cervix, endometrium and breast tissue. This work has led to the suggestion thatHsp27 may be a useful marker in classifying various hormone sensitive tumors.

Spezifität: This antibody detects endogenous levels of HSP27 protein. Species Reactivity: Tested: Human

Synonyme: CMT2F, HMN2B, HSP27, HSP28, Hsp25, SRP27, HS.76067, DKFZp586P1322, MKBP, Hs.78846, LOH11CR1K, MGC133245, 27kDa, Hsp27, hsp1, cb153, hsp25, hsp27, zgc:103437, MGC85307, HSPB1, cmt2f, hsp28, hs.76067, MGC147259

Anwendungen

Applikationshinweise: Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.

Konzentration: 1.0 mg/ml

Reinigung: Aff - Purified

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2

Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.

Beschränkungen: Nur für Forschungszwecke einsetzbar