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beta-Catenin (CTNNB1) Antikörper

Antigen

beta-Catenin (CTNNB1)
Synonyme
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... mehr anzeigen
Klonalität Polyklonal
Wirt
Alternativen

Kaninchen
Reaktivität
Alternativen

Human
Applikation
Alternativen Immunhistochemie (Paraffinschnitte) (IHC (p)), Western Blot (WB)
Produktnummer ABIN498604
Menge 100 µg  (1.0 mg/ml)  (Varianten)
Preis 320,00 €   Zzgl. Versandkosten €20,00 und MWSt
Lieferung nach
Verfügbarkeit Lieferung in 7 bis 10 Werktagen

Produktbeschreibung
Anwendungen Alternativen Sekundärantikörper Varianten zurück nach oben

Produktmerkmale Synonyms: CTNNB1, CTNNB, beta-1 Catenin, beta catenin, beta-Catenin 1, Catenin-beta 1
Weitere Bezeichnung Catenin beta-1
Gen-ID 1499
Swiss-Prot P35222
Kreuzreaktivität Human, Maus, Ratte (Rattus)
Beschreibung The catenins, α, β and γ, are proteins which bind to the highly conserved, intracellularcytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play animportant role mediating cellular adhesion. α-catenin was initially described as anE-cadherin associated protein, and since has been shown to associate with other membersof the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with thecytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as anadhesion molecule. β-catenin has also been found in complexes with the tumorsuppressor protein APC. γ-catenin, also known as plakoglobin, binds with α-catenin andN-cadherin. It has been shown that the transmembrane phosphatase PTPμ associates withcatenin/cadherin complexes and may regulate complex signaling.
Spezifität This antibody detects endogenous levels of Catenin-β protein.
Synonyme CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Anwendungen
Alternativen Sekundärantikörper Varianten zurück nach oben

Applikationshinweise Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Konzentration 1.0 mg/ml
Reinigung Aff - Purified
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2
Lagerung Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing. Shelf life: one year from despatch.
Forschungsgebiet Signaltransduktion
Beschränkungen Nur für Forschungszwecke einsetzbar

Alternativen
Anwendungen Sekundärantikörper Varianten zurück nach oben

Alternativen zu Antigen "beta-Catenin (CTNNB1)", Typ "Antikörper" finden
Wirte Kaninchen (186), Maus (62)
Reaktivitäten Human (230), Maus (154), Ratte (Rattus) (137), Huhn (29), Hund (13), Rind (Kuh) (8), Schwein (6), Xenopus laevis (5), Hamster (2), Affe (1), Kaninchen (1), Schaf (1)
Applikationen Western Blot (WB) (219), Immunfluoreszenz (IF) (72), Immunpräzipitation (IP) (63), Enzyme Immunoassay (EIA) (52), Immunhistochemie (Paraffinschnitte) (IHC (p)) (49), Immunhistochemie (IHC) (40), ELISA (30), Immunhistochemie (Gefrierschnitte) (IHC (fro)) (20), Durchflusszytometrie (FACS) (19), Dot Blot (Dot) (8), Immunzytochemie (ICC) (5), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)) (2), Elektromobilitäts-Experimente (EMSA) (1), Immunoelectron Microscopy (IEM) (1)
Konjugate Biotin (5), Cy3 (2), FITC (2), HRP (2), Alexa Flour 488 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitope pSer33 (10), pSer37 (10), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pSer33/37 (5), pThr41/Ser45 (5), pThr41/pSer45 (5), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer45 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pTyr489 (1)