TNFRSF10A Antikörper (Extracellular Domain) (FITC)

Produktnummer ABIN488158

Dieser Maus Monoklonal Antikörper detektiert spezifisch TNFRSF10A in FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TNFRSF10A Antikörper (Extracellular Domain) (FITC) (ABIN488158)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF10A Antikörper ist konjugiert mit FITC

Applikation: Flow Cytometry (FACS)

Klon: DR-4-02

Produktdetails anti-TNFRSF10A Antikörper (FITC)

Bindungsspezifität: Extracellular Domain

Spezifität: The antibody DR-4-02 recognizes TRAIL-R1 (DR4), a Human Death Receptor 4 (468 amino acids) expressed in most Human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: APO2, DR4, Death receptor 4, TRAIL receptor 1, TRAIL-R1, TNFRSF10A, Tumor necrosis factorreceptor superfamily member 10A, TNF-related apoptosis-inducing ligand receptor 1

Aufreinigung: Size-Exclusion Chromatography

Immunogen: Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of theheavy chain of the Human IgG1.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry analysis: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.1 mg/mL

Buffer: PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (Protease free)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody in the dark at 2-8 °C. DO NOT FREEZE! Avoid prolonged exposure to light.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Andere Bezeichnung: CD261 / TRAILR1

Hintergrund: TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A

Gen-ID: 8797

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity