KCNN2 Antikörper (Internal Region)

Produktnummer ABIN487968

Der Ziege Polyklonal anti-KCNN2 Antikörper (ABIN487968) detektiert spezifisch KCNN2 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh) und Hund.

Kurzübersicht für KCNN2 Antikörper (Internal Region) (ABIN487968)

Target: KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser KCNN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-KCNN2 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-ESYDKHVTYN AER

Spezifität: This antibody is expected to recognize both isoforms of KCNN2 (NP_067627.2, NP_740721.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the Internal region of the protein sequence according to NP_067627.2, NP_740721.1. Genename: KCNN2

Anwendungsinformationen

Applikationshinweise: Peptide ELISA: 1/64000. Western blot: Approx 70 kDa and 20 kDa bands observed in Human Liver lysates (calculatedMW of 63.0 kDa according to NP_067627.2 and of 26.0 kDa according to NP_740721.1). Recommended concentration: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu KCNN2

Target: KCNN2 (Potassium Intermediate/small Conductance Calcium-Activated Channel, Subfamily N, Member 2 (KCNN2))

Andere Bezeichnung: KCNN2

Hintergrund: A widely expressed protein forming a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin.Synonyms: KCNN2, SK2, Small conductance calcium-activated potassium channel protein 2

Gen-ID: 3781

NCBI Accession: NP_067627

UniProt: Q9H2S1